Channel:  The Howard Hughes Medical Institute (HHMI)

1,912 Articles

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Insights into substrate binding and utilization by hyaluronan synthase
Stephens, Z., Karasinska, J., Zimmer, J.
10.1101/2025.10.17.683186 — Posted: 2025-10-18
A genetically-defined population of amygdalofugal neurons promotes suckling and early postnatal growth
Moore, J., Bachmann, L., McElvain, L., Pfaff, S., Dulac, C.
10.1101/2025.10.18.683193 — Posted: 2025-10-18
Structures of folding intermediates on BAM show diverse substrates fold by a uniform mechanism
Thomson, B. D., Marquez, M. D., Rawson, S., dos Santos, T. M. A., Harrison, S. C., Kahne, D.
10.1101/2025.10.16.682720 — Posted: 2025-10-17
Antiviral reverse transcriptases reveal the evolutionary origin of telomerase
Tang, S., Ramirez, J. L., Mestre, M. R., Zhang, D. J., Wang, M., Wiegand, T., Ma, Y., Jovanovic, M., Pinilla-Redondo, R., Sternberg, S. H.
10.1101/2025.10.16.682844 — Posted: 2025-10-16
Accelerating protein design by scaling experimental characterization
Qian, J., Milles, L. F., Wicky, B. I. M., Ragotte, R. J., Motmaen, A., Borst, A. J., Skotheim, R., Ols, S., Coventry, B., Li, X., Kibler, R. D., Goreshnik, I., Exposit, M., Lore, K., Stewart, L., Baker, D.
10.1101/2025.08.05.668824 — Posted: 2025-10-16
Assessment of Nucleic Acid Structure Prediction in CASP16
Kretsch, R. C., Hummer, A. M., He, S., Yuan, R., Zhang, J., Karagianes, T., Cong, Q., Kryshtafovych, A., Das, R.
10.1101/2025.05.06.652459 — Posted: 2025-10-16
Hepatic ceramide synthesis links systemic inflammation to organelle dysfunction in cancer
Liu, Y., Miao, T., Wang, A., Ezequiel, D., Kim, A.-R., Zhang, Z., Sun, X., Binari, R., Asara, J. M., Hu, Y., Goncalves, M., Janowitz, T., Perrimon, N.
10.1101/2025.10.01.679814 — Posted: 2025-10-16
An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics
Picard, C. L., Ichino, L., Buckley, T. J., Boone, B. A., Abuhanna, K. D., Zhang, Y., Behrendt, N. J., May Lei Soe, S., Luo, C., Jacobsen, S. E.
10.1101/2025.10.13.682236 — Posted: 2025-10-15
Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas
St. Laurent, J. D., Xu, G. D., Ying, A. W., Gokbayrak, B., Patil, A., Paulo, J. A., Cervantes, K. S., Chen, S., Feng, W. W., Sankar, A., Same Guerra, D. D., Qi, J., Neel, D. S., Hornick, J. L., Kolin, D. L., Gygi, S., Huntsman, D. G., Wang, Y., Kadoch, C.
10.1101/2025.10.13.681937 — Posted: 2025-10-15
Nascent CUT&Tag captures transcription factor binding after chromatin duplication
Wooten, M., Nguyen, K., Takushi, B. N., Ahmad, K., Henikoff, S.
10.1101/2025.10.13.682212 — Posted: 2025-10-15

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