Channel:  The Howard Hughes Medical Institute (HHMI)

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Oxidative stress sensing by the translation elongation machinery promotes production of detoxifying selenoproteins
Rehfeld, F., Lundstrom, C., Zhang, H., Mendell, J. T.
10.1101/2025.10.13.682107 — Posted: 2025-10-13
Single-sequence deep learning delivers crystal-quality models of covalent K-Ras G12 hotspot complexes
Jung, S., Zheng, Q., Shokat, K.
10.1101/2025.09.16.676163 — Posted: 2025-10-13
Rapid development and field evaluation of a portable CRISPR-based assay for Mpox during the 2025 Sierra Leone outbreak
Gopal, N., Abay, T., Payne, C., Gomez, M., Fofanah, I. U., Rogers, M. M., Kallon, T. P., Kamara, M. S., Suk, H.-J., Sandi, J. D., Brock-Fisher, T., Stachler, E., Allan-Blitz, L.-T., Roach, D. J., Paye, M. F., Wilkason, C., Grant, D. S., Ozonoff, A., Sabeti, P. C.
10.1101/2025.10.08.25337506 — Posted: 2025-10-13
A family of lethal exotoxins defined by cell entry via the Attractin receptor
Viswanatha, R., Lee, D., Robins, W. P., Mameli, E., Hu, Y., Kim, A.-R., Hashmi, Y., Nishida, H., Prakash, G., Butnaru, M., Churchman, L. S., Mohr, S., Mekalanos, J., Perrimon, N.
10.1101/2025.10.08.681221 — Posted: 2025-10-11
Ultra-mild bisulfite outperforms existing methods for 5-methylcytosine detection with low input DNA
He, C., Dai, Q., Baldwin, T., Lyu, R., Daniels, B., Ye, C., Cao, C., Zhu, C., Fan, D., Lin, L., Liu, Y., Wang, Y.
10.1101/2025.10.09.681456 — Posted: 2025-10-11
Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly
Dong, K. X., Ji, H., Luginbuhl, D. J., Luo, L., McLaughlin, C.
10.1101/2025.10.09.681358 — Posted: 2025-10-10
Kinase KEY1 controls pyrenoid condensate size throughout the cell cycle by disrupting phase separation interactions
He, S., Lemma, L. M., Martinez-Calvo, A., He, G., Hennacy, J. H., Wang, L., Ergun, S. L., Rai, A. K., Wang, C., Bunday, L., Kayser-Browne, A., Wang, Q., Brangwynne, C. P., Wingreen, N. S., Jonikas, M. C.
10.1101/2025.10.09.681382 — Posted: 2025-10-10
Cell type- and chromosome-specific chromatin landscapes and DNA replication programs of Drosophila testis tumor stem-cell like cells
Urban, J., Ringwalt, D., Urban, J., Xue, W., Gleason, R., Zhao, K., Chen, X.
10.1101/2025.04.19.649648 — Posted: 2025-10-10
Induction of menstruation in mice reveals the regulation of menstrual shedding
Cevrim, C., Hilgert, N. J., Kaage, A. M., Russell, A. J. C., Goldstein, A. E., Ang, C. J., Gable, J. L. R., Bagamery, L. E., Breznik, A., Di Bella, D. J., Talay, M., Peng, J., O'Neill, K. E., Chen, F., Eddy, S. R., McKinley, K. L.
10.1101/2025.10.08.681007 — Posted: 2025-10-09
Ingestion-activated CGRP neurons control learning but not satiety
Jarvie, B. C., Ravi, A., Nanavati, R., Qui, L., Ly, T., Oh, J. Y., Barnhill, O. K., Knight, Z. A.
10.1101/2025.10.08.681275 — Posted: 2025-10-09

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