Channel:  The Howard Hughes Medical Institute (HHMI)

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Chromatin boundary permeability is controlled by CTCF conformational ensembles
Rudnizky, S., Murray, P. J., Sorensen, E. W., Koenig, T. J. R., Pangeni, S., Merino-Urteaga, R., Chhabra, H., Caccianini, L., Davidson, I. F., Osorio-Valeriano, M., Hook, P. W., Meneses, P., Hao, J., Zarb, J. S., Hatzakis, N. S., Timp, W., Farnung, L., Vos, S. M., Peters, J.-M., Aksimentiev, A., Ha, T.
10.1101/2025.11.25.690553 — Posted: 2026-02-12
The dynamic evolution of panarthropod germ cell specification mechanisms
Kao, J. A., Rivard, E. L., Kapoor, R. R., Extavour, C. G.
10.1101/2025.08.05.668520 — Posted: 2026-02-12
4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity
Skinner, O. S., Miranda, M., Dong, F., Struhl, T., Walker, M. A., Schleifer, G., Henke, M. T., Clardy, J., Hirano, M., De Vivo, D. C., Schon, E. A., Engelstad, K., Siegmund, S. E., Laprise, C., Des Rosiers, C., Sharma, R., Mootha, V. K.
10.64898/2026.02.10.705117 — Posted: 2026-02-12
Learning-dependent feedback by OLM interneurons shapes CA1 representations
Campbell, E. P., Martin, L., Magee, J. C., Grienberger, C.
10.64898/2025.12.21.695825 — Posted: 2026-02-11
Tissue-specific regulation of PNPLA3 promotes lipid remodeling in response to dietary and environmental challenges
Wu, P., Wang, Y., Cohen, J. C., Hobbs, H. H.
10.1101/2025.10.27.684800 — Posted: 2026-02-11
A plasma-based DNA test for quantification of disease burden in acute myeloid leukemia patients undergoing bone marrow transplantation
Wang, Y., Xie, J., Pasca, S., Popoli, M., Ptak, J., Dobbyn, L., Silliman, N., Paul, S., Jones, R. J., Levis, M. J., Curtis, S. D., Douville, C., Shams, C., Guo, M. Z., Mo, S., Gocke, C. D., Malek, S. N., Bollard, C. M., Bettegowda, C., Kinzler, K. W., Vogelstein, B., Papadopoulos, N., Gondek, L. P.
10.64898/2026.02.10.26345949 — Posted: 2026-02-11
Multiple redundant mechanisms account for the majority of gene silencing downstream of DNA methylation
Wang, S., Wu, Z., Li, Z., Movilli, A., He, L., Zhou, Y., Lin, E. K., Chuang, R., Thiri, W. W., Convery, S., Feng, S., Weigel, D., Jacobsen, S. E.
10.64898/2026.02.08.704674 — Posted: 2026-02-10
Whole-Brain Co-Mapping of Gene Expression and NeuronalActivity at Cellular Resolution in Behaving Zebrafish
Marquez Legorreta, E., Fleishman, G. M., Hesselink, L. W., Eddison, M., Smeets, K., Stringer, C., Keller, P. J., Narayan, S., Chen, A. B., Mensh, B. D., Sternson, S. M., Englitz, B., Tillberg, P. W., Ahrens, M. B.
10.64898/2026.02.07.704095 — Posted: 2026-02-10
Cooperative Architecture of Mitochondrial Proteome Homeostasis
Forny, P., Forny, M., Smith, A. J., Sung, A. Y., Liu, K., Pagliarini, D. J.
10.64898/2026.02.06.26345691 — Posted: 2026-02-09
Unbend: Correction of local beam-induced sample motion in cryo-EM images using a 3D spline model
Kong, L., Zottig, X., Elferich, J., Grigorieff, N.
10.1101/2025.09.05.674398 — Posted: 2026-02-07

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