Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines
Lee, J., Stewart, C., Schaefer, A., Leaf, E. M., Park, Y.-J., Asarnow, D., Powers, J. M., Treichel, C., Corti, D., Baric, R., King, N. P., Veesler, D.
10.1101/2023.12.12.571160 — Posted: 2023-12-20
Extreme restructuring of cis-regulatory regions controlling a deeply conserved plant stem cell regulator
Ciren, D., Zebell, S., Lippman, Z.
10.1101/2023.12.20.572550 — Posted: 2023-12-20
Persistence of backtracking by human RNA polymerase II
Yang, K. B., Rasouly, A., Epshtein, V., Martinez, C., Nguyen, T., Shamovsky, I., Nudler, E.
10.1101/2023.12.13.571520 — Posted: 2023-12-19
Missense mutations in CMS22 patients reveal that PREPL has both enzymatic and non-enzymatic functions
Monnens, Y., Theodoropoulou, A., Rosier, K., Bhalla, K., Mahy, A., Vanhoutte, R., Meulemans, S., Cavani, E., Antanasijevic, A., Lemmens, I., Lee, J. A., Spellicy, C. J., Schroer, R. J., Masalli, R. A., Laverty, C. G., Agostinis, P., Pagliarini, D., Verhelst, S., Marcaida, M. J., Rochtus, A., Dal Peraro, M., Creemers, J. W. M.
10.1101/2023.12.18.572145 — Posted: 2023-12-19
The membrane curvature inducing REEP1 proteins generate a novel ER-derived vesicular compartment
Shibata, Y., Mazur, E. E., Pan, B., Hernandez, S. V., Zhang, J., Rapoport, T. A.
10.1101/2023.12.19.572386 — Posted: 2023-12-19
VPS13B is localized at the cis-trans Golgi complex interface and is a functional partner of FAM177A1
Ugur, B., Schueder, F., Shin, J., Hanna, M. G., Wu, Y., Leonzino, M., Su, M., McAdow, A. R., Wilson, C. A., Postlethwait, J., Solnica-Krezel, L., Bewersdorf, J., De Camilli, P.
10.1101/2023.12.18.572081 — Posted: 2023-12-18
Imaging the voltage of neurons distributed across entire brains of larval zebrafish
Wang, Z., Zhang, J., Symvoulidis, P., Guo, W., Zhang, L., Wilson, M. A., Boyden, E. S.
10.1101/2023.12.15.571964 — Posted: 2023-12-16
Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9
Eggers, A. R., Chen, K., Soczek, K. M., Tuck, O. T., Doherty, E. E., Thornton, B. W., Xu, B., Trinidad, M. I., Doudna, J. A.
10.1101/2023.12.14.571777 — Posted: 2023-12-15
Substrate-interacting pore loops of two ATPase subunits determine the degradation efficiency of the 26S proteasome
Martin, A., Lopez-Alfonzo, E. M., Saurabh, A., Zarafshan, S., Presse, S.
10.1101/2023.12.14.571752 — Posted: 2023-12-15
A translation-independent directed evolution strategy to engineer aminoacyl-tRNA synthetases
Soni, C., Prywes, N., Hall, M., Savage, D. F., Schepartz, A., Chatterjee, A.
10.1101/2023.12.13.571473 — Posted: 2023-12-14

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