Channel:  The Howard Hughes Medical Institute (HHMI)

2,708 Articles

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A single-cell atlas of intestinal immune cells across the day-night cycle reveals dynamic populations
Maples, R. W., Quinn, G., Srinivasan, T., Dende, C., Hooper, L. V., Pfeiffer, J. K.
10.64898/2026.01.24.701519 — Posted: 2026-01-26
Comparative Proteomic Profiling of Receptor Kinase Signaling Reveals Key Trafficking Components Enforcing Plant Stomatal Development
Bai, P., Vu, M. H., Komatsu, C., Papoulas, O., Ebine, K., Nozawa, A., Sawasaki, T., Ueda, T., Marcotte, E. M., Torii, K. U.
10.1101/2025.07.20.665823 — Posted: 2026-01-26
TAK1 integrates the NLRP1 inflammasome into the innate immune response to double-stranded RNA
Corley, M. R., Hyodo, A., Toyoda, H. C., Yonemitsu, M. A., Chantharath, A., Hyde, J. L., Mitchell, P. S.
10.64898/2026.01.23.701331 — Posted: 2026-01-25
Nuclear envelope budding is a non-canonical mechanism to export large transcripts in muscle cells
Zaganelli, S., Meehl, J., Abrisch, R. G., Voeltz, G. K.
10.1101/2025.04.18.649598 — Posted: 2026-01-24
Engaging Unstabilized Alkyl Radicals with Pyridoxal Radical Biocatalysis: Enantiodivergent Synthesis of Aliphatic Non-Canonical Amino Acids
Cheng, L., Chen, J., Bo, Z., Zhang, X., Liu, P., Yang, Y.
10.64898/2026.01.21.700944 — Posted: 2026-01-23
Inference of germinal center evolutionary dynamics via simulation-based deep learning
Ralph, D. K., Bakis, A. G., Galloway, J., Vora, A. A., Araki, T., Song, Y. S., DeWitt, W. S., Matsen, F. A.
10.1101/2025.08.12.669950 — Posted: 2026-01-22
Sciphy: A Bayesian phylogenetic framework using sequential genetic lineage tracing data.
Seidel, S., Zwaans, A., Regalado, S., Choi, J., Shendure, J., Stadler, T.
10.1101/2024.10.01.615771 — Posted: 2026-01-22
Cytoplasmic mRNA decay by the anti-viral nuclease RNase L promotes transcriptional repression
Mao, X., Tokamov, S., Pahmeier, F., Lari, A., Xu, J., Harris, E., Glaunsinger, B.
10.1101/2025.07.08.663778 — Posted: 2026-01-19
Modular mRNA LNP design integrates RNA, lipid, and antigen engineering for protective vaccination
Farzani, T., Espinoza, N., M. Manafi, M., R. Welch, S., D. Coleman-McCray, J., Aida-Ficken, V., R. Spengler, J., Bergeron, E., F. Spiropoulou, C., Borges, C., Bielecki, K., Li, L., Shah, D., Paye, M., Rojas, E., N. Spector, S., Samani, P., E. Hensley, L., Ozonoff, A., Sabeti, P.
10.64898/2026.01.17.699915 — Posted: 2026-01-18
B Lymphocyte Protein Factories produced by Hematopoietic Stem Cell Gene Editing
Hartweger, H., Ruprecht, C., Yao, K.-H., Laffont, P., Lima dos Reis, G., Zhou, P., Hägglöf, T., Binet, L., Loewe, M., Hong, J. P., Xiao, T., Sefik, E., Hernandez, B., Gazumyan, A., Jankovic, M., Seaman, M. S., Costa, G., Nelson, S. A., Clark, J., Kanatani, S., Wilson, P. C., Krammer, F., Levashina, E. A., Julien, J.-P., Wardemann, H., Sinnis, P., Stamatatos, L., Flavell, R. A., Nussenzweig, M. C.
10.64898/2026.01.16.699998 — Posted: 2026-01-18

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