Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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A Genome-Wide CRISPR Screen Identifies Sortilin as the Receptor Responsible for Galectin-1 Lysosomal Trafficking
Donnelly, J., Kamber, R. A., Wisnovsky, S., Roberts, D. S., Peltan, E. L., Bassik, M. C., Bertozzi, C. R.
10.1101/2024.01.03.574113 — Posted: 2024-01-03
Phase diversity-based wavefront sensing for fluorescence microscopy
Johnson, C., Guo, M., Schneider, M. C., Su, Y., Khuon, S. C., Reiser, N., Wu, Y., La Riviere, P. J., Shroff, H.
10.1101/2023.12.19.572369 — Posted: 2024-01-02
Mitochondrial choline import regulates purine nucleotide pools via SLC25A48
Verkerke, A. R. P., Shi, X., Abe, I., Gerszten, R. E., Kajimura, S.
10.1101/2023.12.31.573776 — Posted: 2024-01-01
Genome evolution is surprisingly predictable after initial hybridization
Langdon, Q. K., Groh, J. S., Aguillon, S., Powell, D. L., Gunn, T. R., Payne, C. Y., Baczenas, J. J., Donny, A., Dodge, T. O., Du, K., Schartl, M., Rios-Cardenas, O., Gutierrez-Rodriguez, C., Morris, M., Schumer, M.
10.1101/2023.12.21.572897 — Posted: 2023-12-23
PEARL-catalyzed peptide bond formation after chain reversal during the biosynthesis of non-ribosomal peptides
Yu, Y., van der Donk, W.
10.1101/2023.12.23.573212 — Posted: 2023-12-23
Atomic context-conditioned protein sequence design using LigandMPNN
Dauparas, J., Lee, G. R., Pecoraro, R., An, L., Anishchenko, I., Glasscock, C., Baker, D.
10.1101/2023.12.22.573103 — Posted: 2023-12-23
De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles
An, L., Said, M., Tran, L., Majumder, S., Goreshnik, I., Lee, G. R., Juergens, D., Dauparas, J., Anishchenko, I., Coventry, B., Bera, A. K., Kang, A., Levine, P. M., Alvarez, V., Pillai, A., Norn, C., Feldman, D., Zorine, D., Hicks, D. R., Li, X., Sanchez, M. G., Vafeados, D. K., Salveson, P. J., Vorobieva, A. A., Baker, D.
10.1101/2023.12.20.572602 — Posted: 2023-12-21
Identification of a short, single site matriglycan that maintains neuromuscular function in the mouse
Yang, T., Chandel, I., Gonzales, M., Okuma, H., Prouty, S. J., Zarei, S., Joseph, S., Garringer, K. W., Ocampo Landa, S., Yonekawa, T., Walimbe, A. S., Venzke, D. P., Anderson, M. E., Hord, J. M., Campbell, K. P.
10.1101/2023.12.20.572361 — Posted: 2023-12-21
Carcinogenesis is associated with sex-biased tissue environments and imbalances between estrogen receptor alpha and thyroid hormone receptors
Zhang, F., Deng, M.
10.1101/2023.05.20.541565 — Posted: 2023-12-21
Bidirectional substrate shuttling between the 26S proteasome and the Cdc48 ATPase promotes protein degradation
Li, H., Ji, Z., Paulo, J. A., Gygi, S. P., Rapoport, T. A.
10.1101/2023.12.20.572403 — Posted: 2023-12-20

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