Channel:  The Howard Hughes Medical Institute (HHMI)

2,326 Articles

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Homology-mediated transformation of frog-killing fungus Batrachochytrium dendrobatidis illuminates chytrid development and pathogenesis
Brody, S. M., Kalinka, E., Prostak, S. M., Carvalho, T., Man, J., James, T., Fritz-Laylin, L.
10.1101/2025.08.29.673073 — Posted: 2025-08-31
Whole-transcriptome-scale and isoform-resolved spatial imaging of single cells in complex tissues
Cohen, L., Halpern, A., Blosser, T. R., Che, P., Pan, X., Zhuang, X.
10.1101/2025.08.27.672533 — Posted: 2025-08-30
Catalytic pocket of Clr4 (Suv39h) methyltransfer-ase serves as a substrate receptor for Cullin 4-dependent histone H3 ubiquitination
Psenakova, K., Parhard, S. S., Paulo, J. A., Liu, X., Patterson, E. F., Watson, R., Cheek, M. A., Keogh, M., Kalocsay, M., Gygi, S., Farnung, L., Moazed, D.
10.1101/2025.08.28.672867 — Posted: 2025-08-30
A conserved electron transport chain sensitizes Bacteroides to a pore-forming type VI secretion toxin
Ratner, H. K., Duong, B. D., Miao, P., Bertolli, S., Shen, B. A., Mitchell, U., Gallagher, L. A., Radey, M., Peterson, S. B., Mougous, J.
10.1101/2025.08.29.672963 — Posted: 2025-08-29
Endocytome profiling uncovers cell-surface protein dynamics underlying neuronal connectivity
McLaughlin, C., Ji, H., Dong, K., Xu, C., Wong, K. K. L., Li, Z., Luginbuhl, D. J., Xu, C., Lyu, C., Qin, W., Li, J., Udeshi, N., Carr, S. A., Ting, A. Y., Luo, L.
10.1101/2025.08.28.672852 — Posted: 2025-08-29
Impact of 2'-deoxyribo-purine substrates on nonenzymatic RNA template-directed primer extension
Fang, Z., Acikgoz, O., Jia, X., Essex, J., Wen, R., Szostak, J. W.
10.1101/2025.08.29.673048 — Posted: 2025-08-29
The Eukaryotic homology search complex distorts donor DNA structure to probe for homology
Woodhouse, M. V., Hu, J., Wu, M., Qian, J., Inman, J. T., Wang, M. D., Crickard, J. B.
10.1101/2025.08.28.672940 — Posted: 2025-08-28
De novo design of inducibly assembling multi-component filaments
Shen, H., Lynch, E. M., Jameson, N., Decarreau, J., Shi, C., Chen, Z., Sheffler, W., Xu, M., De Yoreo, J. J., Zalatan, J. G., Kollman, J. M., Baker, D.
10.1101/2025.03.26.645066 — Posted: 2025-08-26
Synthetic Phase Variation for Engineered Microbial Consortia
Kratz, M. F., Murray, R. M., Elowitz, M. B.
10.1101/2025.08.25.672192 — Posted: 2025-08-26
Nucleation limited assembly and polarized growth of a de novo-designed allosterically modulatable protein filament
Shen, H., Lynch, E. M., Shi, C., Watson, J. L., Liu, Y., Wu, K., Bai, H., Kim, C. J., Sheffler, W., Derivery, E., De Yoreo, J. J., Kollman, J. M., Baker, D.
10.1101/2024.09.20.613980 — Posted: 2025-08-26

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