Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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The Cas10 nuclease activity relieves host dormancy to facilitate spacer acquisition and retention during type III-A CRISPR immunity
Aviram, N., Shilton, A., Lyn, N., Reis, B. S., Brivanlou, A., Marraffini, L. A.
10.1101/2024.02.11.579731 — Posted: 2024-02-12
Unselfish meiotic drive maintains heterozygosity in a parthenogenetic ant
Lacy, K. D., Hart, T., Kronauer, D. J. C.
10.1101/2024.02.09.579553 — Posted: 2024-02-12
Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications
Cookis, T., Lydecker, A., Sauer, P. V., Kasinath, V., Nogales, E.
10.1101/2024.02.09.579730 — Posted: 2024-02-10
Estimating the reproduction number and transmission heterogeneity from the size distribution of clusters of identical pathogen sequences
Tran-Kiem, C., Bedford, T.
10.1101/2023.04.05.23287263 — Posted: 2024-02-08
Interplay of condensation and chromatin binding underlies BRD4 targeting
Strom, A. R., Eeftens, J. M., Polyachenko, Y., Weaver, C. J., Watanabe, H.-F., Bracha, D., Orlovsky, N. D., Jumper, C. C., Jacobs, W. M., Brangwynne, C. P.
10.1101/2024.02.07.579384 — Posted: 2024-02-07
Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex
Carr, C. R., Crawford, K. H., Murphy, M., Galloway, J. G., Haddox, H. K., Matsen, F. A., Andersen, K. G., King, N. P., Bloom, J. D.
10.1101/2024.02.05.579020 — Posted: 2024-02-06
A Functional and Non-Homuncular Representation of the Larynx in the Primary Motor Cortex of Mice, a Vocal Non-Learner
Vargas, C. D. M., Agravat, R. K., Waidmann, E. N., Bochalis, C., Bermudez, H., Giannakopoulos, T., Jarvis, E. D.
10.1101/2024.02.05.579004 — Posted: 2024-02-06
Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning
Laubscher, E., Wang, X., Razin, N., Dougherty, T., Xu, R., Ombelets, L., Pao, E., Moffitt, J., Yue, Y., Van Valen, D. A.
10.1101/2023.09.03.556122 — Posted: 2024-02-05
Enhancing mitochondrial pyruvate metabolism ameliorates myocardial ischemic reperfusion injury.
Visker, J. R., Cluntun, A. A., Velasco-Silva, J. N., Eberhardt, D. R., Shankar, T. S., Hamouche, R., Ling, J., Kwak, H., Hillas, Y., Aist, I., Tseliou, E., Navankasattusas, S., Chaudhuri, D., Ducker, G. S., Drakos, S. G., Rutter, J.
10.1101/2024.02.01.577463 — Posted: 2024-02-04
Limited genomic signatures of population collapse in the critically endangered black abalone (Haliotis cracherodii)
Wooldridge, B., Orland, C., Enbody, E., Escalona, M., Mirchandani, C. D., Corbett-Detig, R., Kapp, J. D., Fletcher, N., Ammann, K., Raimondi, P., Shapiro, B.
10.1101/2024.01.26.577275 — Posted: 2024-01-29

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