Channel:  The Howard Hughes Medical Institute (HHMI)

2,124 Articles

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ImmunoStruct: a multimodal neural network framework for immunogenicity prediction from peptide-MHC sequence, structure, and biochemical properties
Givechian, K. B., Rocha, J. F., Yang, E., Liu, C., Greene, K., Ying, R., Caron, E., Iwasaki, A., Krishnaswamy, S.
10.1101/2024.11.01.621580 — Posted: 2025-05-01
A CARF-HAD phosphatase effector provides immunity during the type III-A CRISPR-Cas response
Stella, G., Ye, L., Brady, S. F., Marraffini, L. A.
10.1101/2025.04.30.651354 — Posted: 2025-04-30
Anoxia activates CRISPR-Cas immunity in the intestine
Campbell, I. W., Basta, D. W., Zingl, F. G., Sullivan, E. J., Doranga, S., Waldor, M. K.
10.1101/2025.04.30.651551 — Posted: 2025-04-30
Short-term gonadal cultures are sufficient for germline transmission in a songbird
Biegler, M. T., Harter, E., Sidhu, A. V., Szialta, C., Durham, G., Tchernichovski, L., Collier, P., Luo, J.-D., Wang, W., MacIsaac, R., Belay, K., Carroll, T., Keyte, A. L., Jarvis, E. D.
10.1101/2025.04.25.650428 — Posted: 2025-04-29
PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation
Wang, S., Baumert, R., Sejourne, G., Sivadasan Bindu, D., Dimond, K., Sakers, K., Vazquez, L., Moore, J. L., Tan, C. X., Takano, T., Rodriguez, M. P., Brose, N., Bradley, L., Lessing, R., Soderling, S. H., La Spada, A. R., Eroglu, C.
10.1101/2023.04.09.536178 — Posted: 2025-04-29
Distinct waves of ovarian follicles contribute to mouse oocyte production
Yin, Q., Spradling, A. C.
10.1101/2024.05.30.596686 — Posted: 2025-04-29
Separable Dorsal Raphe Dopamine Projections Mimic the Facets of a Loneliness-like State
Lee, C. R., Matthews, G. A., Lemieux, M. E., Wasserlein, E. M., Borio, M., Miranda, R. L., Keyes, L. R., Schneider, G. P., Jia, C., Tran, A., Aloboudi, F., Chan, M. G., Peroni, E., Pereira, G. S., Lopez-Moraga, A., Palle, A., Kimchi, E. Y., Padilla-Coreano, N., Wichmann, R., Tye, K. M.
10.1101/2025.02.03.636224 — Posted: 2025-04-29
Divergence of germ cell-less roles in germ line development across insect species
Kao, J., Ewen-Campen, B., Extavour, C. G.
10.1101/2025.03.26.645619 — Posted: 2025-04-29
Spatiotemporal Analysis of Remyelination Reveals a Concerted Interferon-Responsive Glial State That Coordinates Immune Infiltration
Dolan, M.-J., Rakosi-Schmidt, R., Garcia, E., Lin, Y., Nadaf, N. M., Dixon, J., Guo, S., Morshed, N., Depp, C., Doman, J., Xia, J., Jäntti, H., Stevens, B., Macosko, E. Z.
10.1101/2025.04.22.649486 — Posted: 2025-04-29
Tanycyte Bmal1 sex-specifically regulates weight gain and hypothalamic neurogenesis in female mice
Iascone, D. M., Pivarshev, P., Yang, J., Lopez Valencia, M., Noya, S. B., Lin, H., Anafi, R. C., Bedont, J. L., Sehgal, A.
10.1101/2025.04.21.649851 — Posted: 2025-04-28

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