Channel:  The Howard Hughes Medical Institute (HHMI)

2,398 Articles

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Lipid bilayer thinning near a ubiquitin ligase selects ER membrane proteins for degradation
Pisa, R., Rapoport, T. A.
10.1101/2025.10.31.685944 — Posted: 2025-11-01
B lymphocytes that enter the germinal center late preferentially differentiate into memory cells that recognize subdominant epitopes
Zhou, P., Hartweger, H., MacLean, A. J., Ramos, V., Yao, K.-h., Hernandez, B., Wang, Z., Gazumyan, A., Nussenzweig, M. C.
10.1101/2025.10.30.685663 — Posted: 2025-11-01
Sleep-dependent clearance of brain lipids by peripheral blood cells
Cho, B., Youngstrom, D. E., Killiany, S., Guevara, C., Randolph, C. E., Beveridge, C. H., Saklani, P., Chopra, G., Sehgal, A.
10.1101/2025.10.30.685668 — Posted: 2025-10-31
larch: mapping the parsimony-optimal landscape of trees for directed exploration
Barker, M., Milanov, O., Dumm, W., Rich, D., Turakhia, Y., Matsen, F. A.
10.1101/2025.10.29.685337 — Posted: 2025-10-31
HaloTrace: A spatiotemporally precise fluorescent readout of blood-brain barrier permeability in mice
Zucker, H. L., Konshina, E., Mitchell, P., Gu, C.
10.1101/2025.10.30.685531 — Posted: 2025-10-31
Trimodal brain-wide ultrasound imaging of brain-tumor interaction
Rabut, C., Shivaei, S., Heiles, B., Shapiro, M. G.
10.1101/2025.10.29.685462 — Posted: 2025-10-31
Mutational scanning of TnpB reveals latent activity for genome editing
Thornton, B. W.-L., Weissman, R. F., Rodriguez, J. E., Tran, R. V., Duong, B. T., Terrace, C. I., Nagalakshmi, U., Austin, G., Groover, E. D., Wang, F. Z., Park, J.-U., Georgieva, V., Tartaglia, J., Cho, M.-J., Dinesh-Kumar, S., Doudna, J. A., Savage, D.
10.1101/2025.02.11.637750 — Posted: 2025-10-30
Human Coronavirus HKU1 Neutralizing Monoclonal Antibodies Target Diverse Epitopes Within and Around the TMPRSS2 Receptor Binding Site
Wang, L., Joseph, J., Vasquez, S., Wrapp, D., Sheahan, T. P., Dzuvor, C. K. O., Rosen, O., Kirchdoerfer, R., Abiona, O. M., Hammond, C., Shi, W., Moak, S. P., Kong, W.-P., Zhang, Y., Eso, M. R., Brown, A. J., Ward, A., Baric, R. S., McLellan, J. S., Pierson, T. C., Mascola, J., Graham, B. S., Yassine, H., Barnes, C. O., Corbett-Helaire, K. S.
10.1101/2025.10.29.685445 — Posted: 2025-10-30
Sexual dimorphism in the complete connectome of the Drosophila male central nervous system
Berg, S., Beckett, I. R., Costa, M., Schlegel, P., Januszewski, M., Marin, E. C., Nern, A., Preibisch, S., Qiu, W., Takemura, S.-y., Fragniere, A. M. C., Champion, A. S., Adjavon, D.-Y., Cook, M., Gkantia, M., Hayworth, K. J., Huang, G. B., Kampf, F., Katz, W. T., Lu, Z., Ordish, C., Paterson, T., Stuerner, T., Trautman, E. T., Whittle, C. R., Burnett, L. E., Hoeller, J., Li, F., Loesche, F., Morris, B. J., Pietzsch, T., Pleijzier, M. W., Silva, V., Yin, Y., Ali, I., Bates, A. S., Beresford, R. J., Bogovic, J., Brooks, P., Cachero, S., Canino, B. S., Chaisrisawatsuk, B., Clements, J., Crowe, A
10.1101/2025.10.09.680999 — Posted: 2025-10-30
Alternative splicing of synaptotagmin 7 regulates oligomerization and short-term synaptic plasticity
Mehta, N., Larson, D. T., Salaka, R. J., Wozney, M., Subramani, S., Mishra, S., Kaur, S., Jain, A., Chapman, E. R.
10.1101/2025.10.27.684894 — Posted: 2025-10-28

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