Channel:  The Howard Hughes Medical Institute (HHMI)

2,712 Articles

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Inter-individual variation of cellular and gene-expression properties of the human striatum
Burger, S., Yoo, O., Nemesh, J., Muratoglu, E., Vanderburg, C., Yuan, J., Shakir, K., Mello, C. J., Rayan, N. A., Milidantri, J., Kim, K., Drouin, S., Finn, E., Gao, H., Budnik, N., Goldman, M., Fritch, H., Genovese, G., Hogan, M., Catalini, O., Kashin, S., Rockweiler, N., Wysoker, A., Macaisa, L., Reese, L., Flowers, K., Kraft, A. W., Fleming, S. J., Coe, M., Gunaratne, R., Spina, L., Crombie, C., Mohsin, A., Kamitaki, N., Macosko, E. Z., Ichihara, K., McCarroll, S. A.
10.64898/2026.03.20.713160 — Posted: 2026-03-23
Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer
Koochaki, P., Qiu, B., Coker, J. A., Earsley, A., Wang, N. S., Romigh, T., Goins, C. M., Salem, C., Mi, D., Days, E., Bauer, J., Stauffer, S. R., Boudker, O., Chakraborty, A. A.
10.1101/2025.07.03.663021 — Posted: 2026-03-19
Faf1 accelerates p97-mediated protein unfolding by promoting ubiquitin engagement
Liao, Z., Arkinson, C., Martin, A.
10.1101/2025.10.27.684972 — Posted: 2026-03-19
Midgestation metabolic constraint in purine metabolism drives distinct strategies for placenta and fetal growth
Xu, W., De La Cruz, N., Woods, A., Lokshtanov, D., Gao, S., Khan, N. A., Wright, S., Florian-Rodriguez, M., McIntire, D. D., Duryea, E. L., Nelson, D. B., Spong, C. Y., Herrera, C. L., Hanna, J. H., Srivatsan, S. R., Aguilera Castrejon, A., Solmonson, A.
10.64898/2026.03.18.712680 — Posted: 2026-03-18
Heterotypic intercellular adhesion tunes efficiency of cell-on-cell migration
Kuyyamudi, C., Ghosh, S., Extavour, C. G.
10.1101/2025.08.29.673192 — Posted: 2026-03-18
Reconstituting Mouse Embryogenesis Ex Utero from Gastrulation to Fetal Development Reveals Maternally Independent Metabolic Programs
Lokshtanov, D., Gao, S. M., Xu, W., Kosman, A., Roncato, F., De La Cruz, N., Khan, N. A., Woods, A., Campbell, I., Woehler, A., Christoforou, C., Ding, L., Hu, A., Copeland, M., Wang, L., Yang, X., Raley, C., Delventhal, K., Herrera, A., Valente, A., Wright, S., Gomez-Cesar, E., Shlomo, R., Golenchenko, S., Oldak, B., Yilmaz, A., Gurhan-Sevinc, G., Comar, M.-Y., Viukov, S., Novershtern, N., Zhang, H., Duong, T., Li, L., Khatib, N., Kakun, R. R., Espinosa-Medina, I., Florian-Rodriguez, M. E., LaManno, G., Tillberg, P. W., Wang, M. C., Maza, I., Srivatsan, S., Solmonson, A., Hanna, J. H., Aguile
10.64898/2026.03.17.710314 — Posted: 2026-03-18
UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism
Nguyen, P. T., Wu, Z., Kim, D., Ogu, T., Yin, S., Sondhi, V., Cai, F., Tippetts, T. S., Jen, A., Shishkova, E. J., Cai, L., Dumesnil, D., Cervantes, M., Chen, H., Mishra, P., Coon, J., Hoxhaj, G., Ni, M., DeBerardinis, R. J.
10.64898/2026.03.18.712693 — Posted: 2026-03-18
Divergent C. elegans toxin alleles are suppressed by distinct mechanisms
Zdraljevic, S., Walter-McNeill, L., Bruni, G., Marquez, H., Collins, J., Leighton, D. H. W., Alexander, N., Bloom, J. S., Kruglyak, L.
10.1101/2024.04.26.591160 — Posted: 2026-03-18
Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures
Ahn, J. J., Yu, T. C., Dadonaite, B., Radford, C. E., Bloom, J. D.
10.64898/2026.01.05.697808 — Posted: 2026-03-18
Genome-scale functional mapping of the mammalian whole brain with in vivo Perturb-seq
Shi, T., Korshunova, M., Kim, S., DeTomaso, D., Zheng, X., Vishvanath, L., Nyasulu, T., Huynh, N., Sun, A., Thompson, P. C., Zhang, Y., Wigdor, E. M., Rohani, N., Ali, S., Qiu, H., Geralt, M., Zhao, Z., Rabhi, S., Yao, Z., van Velthoven, C. T., Nery, J. R., Castanon, R. G., Dicks, S., Chen, T. J., Ecker, J. R., Zeng, H., Zheng, G. X., Sanders, S. J., Sundaram, L., Jin, X.
10.64898/2026.03.16.711480 — Posted: 2026-03-18

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