Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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The LuxO-OpaR quorum-sensing cascade differentially controls Vibriophage VP882 lysis-lysogeny decision making in liquid and on surfaces
Santoriello, F., Bassler, B. L.
10.1101/2024.04.02.587679 — Posted: 2024-04-02
Ascorbate depletion increases quiescence and self-renewal potential in hematopoietic stem cells and multipotent progenitors
Comazzetto, S., Cassidy, D., DeVilbiss, A. W., Jeffery, E. C., Ottesen, B. R., Reyes, A. R., Muh, S., Mathews, T. P., Chen, B., Zhao, Z. P., Morrison, S. J.
10.1101/2024.04.01.587574 — Posted: 2024-04-02
Broadly neutralizing antibodies against emerging delta-coronaviruses
Rexhepaj, M., Park, Y.-J., Perruzza, L., Asarnow, D., McCallum, M., Culap, K., Saliba, C., Leoni, G., Balmeli, A., Yoshiyama, C., Dickinson, M. S., Quispe, J., Brown, J. T., Tortorici, M. A., Sprouse, K. R., Taylor, A. L., Starr, T. N., Corti, D., Begnini, F., Veesler, D.
10.1101/2024.03.27.586411 — Posted: 2024-04-01
Directed Evolution of Acoustic Reporter Genes Using High-Throughput Acoustic Screening
Hurt, R. C., Jin, Z., Soufi, M., Wong, K. K., Sawyer, D. P., Shen, H. K., Dutka, P., Deshpande, R., Zhang, R., Mittelstein, D. R., Shapiro, M. G.
10.1101/2024.03.30.587094 — Posted: 2024-04-01
NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis
Parolia, A., Eyunni, S., Verma, B. K., Young, E., Liu, L., George, J., Aras, S., Das, C. K., Mannan, R., ur Rasool, R., Luo, J., Carson, S. E., Mitchell-Velasquez, E., Liu, Y., Xiao, L., Gajjala, P. R., Jaber, M., Wang, X., He, T., Qiao, Y., Pang, M., Zhang, Y., Alhusayan, M., Cao, X., Tavana, O., Hou, C., Wang, Z., Ding, K., Chinnaiyan, A. M., Asangani, I. A.
10.1101/2024.02.22.581560 — Posted: 2024-03-29
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimers disease brain by a strain-relief mechanism
Hou, K., Ge, P., Sawaya, M. R., Dolinsky, J. L., Yang, Y., Jiang, Y. X., Lutter, L., Boyer, D. R., Cheng, X., Pi, J., Zhang, J., Lu, J., Yang, S., Yu, Z., Feigon, J., Eisenberg, D. S.
10.1101/2024.03.25.586668 — Posted: 2024-03-29
Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers
Tang, J., Weiser, N. E., Wang, G., Chowdhry, S., Curtis, E. J., Zhao, Y., Wong, I. T.-L., Marinov, G. K., Li, R., Hanoian, P., Tse, E., Hansen, R., Plum, J., Steffy, A., Milutinovic, S., Meyer, S. T., Altemose, N., Curtis, C., Greenleaf, W. J., Bafna, V., Benkovic, S. J., Pinkerton, A. B., Kasibhatla, S., Hassig, C. A., Mischel, P. S., Chang, H. Y.
10.1101/2024.03.29.586681 — Posted: 2024-03-29
The Molecular Architecture of the Nuclear Basket
Singh, D., Soni, N., Hutchings, J., Echeverria, I., Shaikh, F., Duquette, M., Suslov, S., Li, Z., van Eeuwen, T., Molloy, K., Shi, Y., Wang, J., Guo, Q., Chait, B. T., Fernandez-Martinez, J., Rout, M. P., Sali, A., Villa, E.
10.1101/2024.03.27.587068 — Posted: 2024-03-28
Expanding the genetics and phenotypes of ocular congenital cranial dysinnervation disorders
Jurgens, J. A., Barry, B. J., Chan, W.-M., MacKinnon, S., Whitman, M. C., Matos Ruiz, P. M., Pratt, B. M., England, E. M., Pais, L., Lemire, G., Groopman, E., Glaze, C., Russell, K. A., Singer-Berk, M., Di Gioia, S. A., Lee, A. S., Andrews, C., Shaaban, S., Wirth, M. M., Bekele, S., Toffoloni, M., Bradford, V. R., Foster, E. E., Berube, L., Rivera-Quiles, C., Mensching, F. M., Sanchis-Juan, A., Fu, J. M., Wong, I., Zhao, X., Wilson, M. W., Weisburd, B., Lek, M., Ocular CCDD Phenotyping Consortium, , Brand, H., Talkowski, M. E., MacArthur, D. G., O'Donnell-Luria, A., Robson, C. D., Hunter, D.
10.1101/2024.03.22.24304594 — Posted: 2024-03-26
A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan
Jayne, L., Lavin-Peter, A., Roessler, J., Tyshkovskiy, A., Antoszewski, M., Ren, E., Markovski, A., Sun, S., Yao, H., Sankaran, V. G., Gladyshev, V. N., Brooke, R. T., Horvath, S., Griffith, E. C., Hrvatin, S.
10.1101/2024.03.20.585828 — Posted: 2024-03-25

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