Channel:  The Howard Hughes Medical Institute (HHMI)

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Barcoded monoclonal embryoids are a potential solution to confounding bottlenecks in mosaic organoid screens
Regalado, S. G., Qiu, C., Lalanne, J.-B., Martin, B. K., Duran, M., Trapnell, C., Keith, A., Domcke, S., Shendure, J.
10.1101/2025.05.23.655669 — Posted: 2025-07-23
Temperate phages enhance host fitness via RNA-guided flagellar remodeling
Walker, M. W. G., Richard, E., Wiegand, T., Wang, J., Yang, Z., Casas-Ciniglio, A. A., Hoffmann, F. T., Shahnawaz, H., Gaudet, R. G., Arpaia, N., Fernandez, I. S., Sternberg, S. H.
10.1101/2025.07.22.666180 — Posted: 2025-07-22
Pangenome discovery of missing autism variants
Sui, Y., Lin, J., Noyes, M. D., Kwon, Y., Wong, I., Koundinya, N., Harvey, W. T., Wu, M., Hoekzema, K., Munson, K. M., Garcia, G. H., Knuth, J., Wertz, J., Wang, T., Hennick, K., Karunakaran, D., Polo Prieto, R. A., Meyer-Schuman, R., Cherry, F., Pehlivan, D., Suter, B., Gustafson, J. A., Miller, D. E., Human Pangenome Reference Consortium, , Berk-Rauch, H., Nowakowski, T. J., Chakravarti, A., Zoghbi, H. Y., Eichler, E. E.
10.1101/2025.07.21.25331932 — Posted: 2025-07-22
Mouse pups lacking a cerebral cortex develop abnormal vocal behavior
Boyd, J. L., Vargas, C., Jarvis, E. D.
10.1101/2025.07.17.665371 — Posted: 2025-07-22
Chromosome scale genomes of two invasive Adelges species enablevirtual screening for selective adelgicides
Glendening, A. M., Stephens, C., Vuruputoor, V. S., Chaganti, T., Myles, M., Stern, D. L., Abdelalim, M., Juang, Y.-P., Hogenhout, S. A., Mathers, T. C., Pauloski, N., Cernak, T. A., Wegrzyn, J. L., Fetter, K. C.
10.1101/2024.11.21.624573 — Posted: 2025-07-22
Repulsive interactions instruct synaptic partner matching in an olfactory circuit
Li, Z., Lyu, C., Xu, C., Hu, Y., Luginbuhl, D. J., Caspi-Lebovic, A. B., Priest, J. M., Özkan, E., Luo, L.
10.1101/2025.03.01.640985 — Posted: 2025-07-19
Long-read sequencing of trios reveals increased germline and postzygotic mutation rates in repetitive DNA
Noyes, M. D., Sui, Y., Kwon, Y., Koundinya, N., Wong, I., Munson, K. M., Hoekzema, K., Kordosky, J., Garcia, G. H., Knuth, J., Lewis, A. P., Eichler, E. E.
10.1101/2025.07.18.665621 — Posted: 2025-07-19
Rewiring an olfactory circuit by altering the combinatorial code of cell-surface proteins
Lyu, C., Li, Z., Xu, C., Kalai, J., Luo, L.
10.1101/2025.03.01.640986 — Posted: 2025-07-19
Neuroligin-3 interaction with CSPG4 regulates normal and malignant glial precursors through PIEZO1
Gillespie, S. M., Kim, Y. S., Geraghty, A. C., Yalcin, B., Mancusi, R., Hysinger, J., Ivec, A. E., Reed, J., Drexler, R., Quezada, M., Malacon, K., Woo, P. J., Yang, A., Lam, M., Pan, Y., Zuchero, J. B., Trotter, J., Monje, M.
10.1101/2025.07.12.664340 — Posted: 2025-07-17
Complete chromosome 21 centromere sequencing of families with Down syndrome reveals centromere size asymmetry
Mastrorosa, F. K., Daponte, A., Wertz, J., Rozanski, A. N., Harvey, W. T., Porubsky, D., Knuth, J., Garcia, G., Ayllon, M., Munson, K. M., Hoekzema, K., He, W., Sherman, S. L., Allen, E. G., Rosser, T. C., Catacchio, C. R., Ventura, M., Logsdon, G. A., Eichler, E. E.
10.1101/2024.02.25.581464 — Posted: 2025-07-16

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