Channel:  The Howard Hughes Medical Institute (HHMI)

2,697 Articles

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How many genes can CRISPR edit to engineer complex adaptations?
Kyung, J., Esfahanian, M., Mann, J., Koke, E., Pham, K., Peng, Y., Exposito-Alonso, M.
10.64898/2026.05.21.726991 — Posted: 2026-05-23
Entrenchment of germline amino-acid differences in antibody affinity maturation
Harel, N., Sung, K., Dumm, W., Johnson, M. M., Rich, D., Fukuyama, J., Haddox, H. K., Matsen, F. A.
10.64898/2026.04.21.720000 — Posted: 2026-05-23
Developmental conversion of the nucleolus into an RNA Polymerase II transcriptional platform in Drosophila spermatocytes
Fingerhut, J. M. M., Park, J. I., Li, R. Y., Lannes, R., Ashok, A., Yamashita, Y. M.
10.64898/2026.05.20.726666 — Posted: 2026-05-23
Transient cell states encode positional information to direct asymmetric growth
Lee, T. A., Gamnerdsiri, K., Illouz-Eliaz, N., Nobori, T., Nery, J. R., Jow, B., Liem, M., O'Connor, C., Ecker, J. R.
10.64898/2026.05.21.726925 — Posted: 2026-05-22
Native yeast kinetochore structures identify an essential inner kinetochore interaction
Jiang, M., Hu, C., Hedouin, S., Andrade Latino, A., Arimura, Y., Stergachis, A., Biggins, S.
10.64898/2026.01.30.702844 — Posted: 2026-05-21
A pilot study for whole proteome tagging in C. elegans
Eroglu, M., Hobert, O.
10.64898/2026.02.09.704846 — Posted: 2026-05-21
Human vein-to-artery endothelial cell fate transition is driven by VEGF/ERK activation and PI3K inhibition
Amir-Ugokwe, Z., Red-Horse, K., Loh, K. M., Ang, L. T., Pyke, A., Trimm, E., Chakraborty, M., Fan, X.
10.64898/2025.12.17.694993 — Posted: 2026-05-20
Nucleolar Dynamics During Oogenesis
Li, R., McKown, G., Tsuchiya, D., Mattingly, M., Galligos, A., Diez, M., Lu, J. F., McKinney, M. C., McKinney, S., Rubinstein, B., Corbin, T. J., McClain, M., Carmichael, C., Hassebroek, V. A., Nowotarski, S. H., Gerton, J. L., Kostova, K.
10.64898/2026.05.19.726235 — Posted: 2026-05-20
Hidden symmetries in network connectivity support ring attractor dynamics in the fly's neural compass
Hulse, B. K., Aneesh, P. B., Romani, S., Jayaraman, V., Hermundstad, A. M.
10.64898/2026.05.18.725766 — Posted: 2026-05-20
Phylogenetically estimated neutral rates and fitness effects of mutations to influenza proteins
Haddox, H. K., Hinrichs, A. S., Jennings-Shaffer, C., Johnson, K., Benton, C. T., Galloway, J. G., Bloom, J. D., Matsen, F. A.
10.64898/2026.05.18.725477 — Posted: 2026-05-20

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