Channel:  The Howard Hughes Medical Institute (HHMI)

2,124 Articles

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Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503
LaVigne, C. A., Han, J., Zhang, H., Cho, S., Kim, M., Sethia, K., Evers, B. M., Acharya, A., Chang, T.-C., Mendell, J. T.
10.1101/2025.06.30.662380 — Posted: 2025-07-01
SNARE disassembly requires Sec18/NSF side-loading
Khan, Y. A., White, K. I., Pfuetzner, R. A., Singal, B., Esquivies, L., Mckenzie, G., Liu, F., DeLong, K., Choi, U. B., Montabana, E., Mclaughlin, T., Wickner, W. T., Brunger, A. T.
10.1101/2024.08.30.610324 — Posted: 2025-06-30
OocystMeter, a machine-learning algorithm to count and measure Plasmodium oocysts, reveals clustering patterns in the Anopheles midgut
Peng, D., Marrogi, E., Nelson, E., Liu, Q., Rinvee, T. A., de Vries, L. E., Thornburg, K., Singh, N., Shaw, W. R., Catteruccia, F.
10.1101/2025.06.28.662088 — Posted: 2025-06-29
Prioritizing replay when future goals are unknown
Sagiv, Y., Akam, T., Witten, I., Daw, N. D.
10.1101/2024.02.29.582822 — Posted: 2025-06-27
Histone diversity in the archaeal domain of life
Laursen, S. p., Luger, K.
10.1101/2025.06.26.661778 — Posted: 2025-06-27
5-azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia
Gao, B., Li, Y., Zhao, L., Zou, Z., Ma, X., Hong, J., Xiang, J., Dou, X., Yang, F.-C., Xu, M., He, C.
10.1101/2025.06.24.661348 — Posted: 2025-06-27
A cell-based scrambling assay reveals phospholipid headgroup preference of TMEM16F on the plasma membrane
Teo, C. F., Tuomivaara, S. T., van Hilten, N., Crottes, D., Jan, Y. N., Grabe, M., Jan, L. Y.
10.1101/2025.06.25.661602 — Posted: 2025-06-27
Early transcriptional signatures of MeCP2 positive and negative cells in Rett syndrome
Li, Y., Anderson, A. G., Qi, G., Wu, S.-R., Revelli, J.-P., Liu, Z., Zoghbi, H. Y.
10.1101/2025.06.26.661761 — Posted: 2025-06-26
Direct observation of interdependent and hierarchical kinetochore assembly on individual centromeres
Hu, C., Popchock, A. R., Latino, A. A., Asbury, C. L., Biggins, S.
10.1101/2025.06.25.661565 — Posted: 2025-06-26
Magnesium depletion unleashes two unusual modes of colistin resistancewith different fitness costs
Hsieh, Y.-Y. P., O'Keefe, I. P., Sun, W., Wang, Z., Yang, H., Vu, L. M., Ernst, R. K., Dandekar, A. A., Malik, H. S.
10.1101/2024.10.15.618514 — Posted: 2025-06-25

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