Channel:  The Howard Hughes Medical Institute (HHMI)

2,398 Articles

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Drosophila maintain a consistent navigational goal angle for days to weeks
Weisman, J. L., Mohren, T. L., Ryu, J. D., Wyse, M. Z., Dias-Ferreira, E., Maimon, G.
10.64898/2025.12.09.693277 — Posted: 2025-12-11
Engineering immunotoxin-equipped effector cells and evaluation in primary human immune cells
Pearlman, A. H., Mog, B. J., Hwang, M. S., Rincon-Torroella, J., DiNapoli, S. R., Paul, S., Douglass, J., Hsiue, E. H.-C., Glavaris, S. A., Pardoll, D. M., Papadopoulos, N., Kinzler, K. W., Bettegowda, C., Zhou, S., Vogelstein, B., Konig, M. F.
10.64898/2025.12.09.691975 — Posted: 2025-12-11
Design of Orthogonal Far-Red, Orange and Green Fluorophore-binding Proteins for Multiplex Imaging
Tran, L., Klein, S., Sharma, S., Juergens, D., Decarreau, J., Liu, B., Wang, Y., Bera, A. K., Kang, A., Woods, J., Joyce, E., Vafeados, D. K., Roullier, N., Chen, W., Lee, G. R., Lavis, L. D., Mahamid, J., An, L., Baker, D.
10.1101/2025.08.03.668343 — Posted: 2025-12-10
Structural basis of stepwise G protein activation by a viral chemokine receptor
Jude, K. M., Suomivuori, C.-M., Waghray, D., Maeda, S., Fujiyoshi, Y., Inoue, A., Garcia, K. C., Tsutsumi, N.
10.64898/2025.12.10.692789 — Posted: 2025-12-10
Multimodal cell lineage reconstruction in the hindbrain reveals a link between progenitor origin and activity patterning
Blanc, M., Meister, L., Lemon, W. C., Fiuza, U.-M., Keller, P. J., Espinosa-Medina, I., Pujades, C.
10.1101/2025.11.14.688499 — Posted: 2025-12-09
High-efficiency, transgene-free plant genome editing by viral delivery of an engineered TnpB
Nagalakshmi, U., Rodriguez, J. E., Nguyen, T., Weissman, R. F., Thornton, B. W., Savage, D. F., Dinesh-Kumar, S. P.
10.64898/2025.12.05.692691 — Posted: 2025-12-09
Modeling tissue-specific Drosophila metabolism identifies high sugar diet-induced metabolic dysregulation in muscle at reaction and pathway levels
Moon, S. J., Hu, Y., Dzieciatkowska, M., Kim, A.-R., Asara, J. M., D'Alessandro, A., Perrimon, N.
10.1101/2024.04.24.591006 — Posted: 2025-12-09
Inhibition of FicD-mediated AMPylation and deAMPylation by Isoprenoid Diphosphates
Blevins, A. M., Peng, W., Kinch, L., Monshad, Z., Paredes, A. G., Volz, C., Rutter, J., Casey, A., Hicks, K., Orth, K.
10.64898/2025.12.08.693056 — Posted: 2025-12-08
Structure and evolution-guided design of minimal RNA-guided nucleases
Skopintsev, P., Esain-Garcia, I., DeTurk, E. C., Yoon, P. H., Zhou, Z., Weiss, T., Kamalu, M., Chamraj, A., Loi, K. J., Langeberg, C. J., Boger, R., Nisonoff, H., Karp, H. M., Chen, L., Shi, H., Vohra, K., Banfield, J. F., Cate, J. H. D., Jacobsen, S. E., Doudna, J. A.
10.64898/2025.12.08.692503 — Posted: 2025-12-08
Brain-immune interactions generate pathogen-specific sickness states
Sullivan, Z. A., Wong, B. J., Kapoor, V., Vincze, P. K., Kaplan, H. S., Giraudet, P., Watson, B. R., Misherghi, A., Lourido, S., Moffitt, J. R., Dulac, C.
10.64898/2025.12.06.692770 — Posted: 2025-12-08

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