Channel:  The Howard Hughes Medical Institute (HHMI)

2,398 Articles

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Modular mRNA LNP design integrates RNA, lipid, and antigen engineering for protective vaccination
Farzani, T., Espinoza, N., M. Manafi, M., R. Welch, S., D. Coleman-McCray, J., Aida-Ficken, V., R. Spengler, J., Bergeron, E., F. Spiropoulou, C., Borges, C., Bielecki, K., Li, L., Shah, D., Paye, M., Rojas, E., N. Spector, S., Samani, P., E. Hensley, L., Ozonoff, A., Sabeti, P.
10.64898/2026.01.17.699915 — Posted: 2026-01-18
B Lymphocyte Protein Factories produced by Hematopoietic Stem Cell Gene Editing
Hartweger, H., Ruprecht, C., Yao, K.-H., Laffont, P., Lima dos Reis, G., Zhou, P., Hägglöf, T., Binet, L., Loewe, M., Hong, J. P., Xiao, T., Sefik, E., Hernandez, B., Gazumyan, A., Jankovic, M., Seaman, M. S., Costa, G., Nelson, S. A., Clark, J., Kanatani, S., Wilson, P. C., Krammer, F., Levashina, E. A., Julien, J.-P., Wardemann, H., Sinnis, P., Stamatatos, L., Flavell, R. A., Nussenzweig, M. C.
10.64898/2026.01.16.699998 — Posted: 2026-01-18
Discovery of a Human Metabolite that Mimics the Bacterial Quorum-Sensing Autoinducer AI-2
Shine, E., Valastyan, J. S., Ying, V. Y., Huang, J. Z., Seyedsayamdost, M. R., Bassler, B. L.
10.64898/2026.01.16.699917 — Posted: 2026-01-17
Monitoring of plasma and urine tumor-derived DNA to inform bladder-sparing approaches for patients with muscle-invasive bladder cancer
Galsky, M. D., Izadmehr, S., Yu, M., Curtis, S. D., Douville, C., Popoli, M., Ptak, J., Dobbyn, L., Silliman, N., Chan, K. G., Dorff, T. B., Cetnar, J. P., O'Neil, B., D'Souza, A., Mamtani, R., Kyriakopoulos, C. E., Brody, R., Sadimin, E., Mehrazin, R., Chowell, D., Sfakianos, J., Daneshmand, S., Pal, S. K., Bettegowda, C., Kinzler, K. W., Papadopoulos, N., Vogelstein, B., Wang, Y.
10.64898/2026.01.14.26344033 — Posted: 2026-01-16
Hypomethylation on cfDNA within transposable elements can predict ovarian malignancy in women with adnexal masses
Weigert, M., Cui, X., Zhang, P., Kowitwanich, K., West-Szymanski, D., Rauch, S., Zhang, W., He, C., Lengyel, E.
10.64898/2026.01.14.26344128 — Posted: 2026-01-16
Tumor-induced orexigenic imbalance lowers protein appetite and drives early organ wasting symptoms
Petsakou, A., Filine, E., Li, M., Chen, Y., Zheng, A., Perrimon, N.
10.1101/2025.01.02.631110 — Posted: 2026-01-16
Modular gene tagging in C. elegans
Hefel, A., Kruse, K., Wall, K., Jorgensen, S. B., Ng, K. H., Stolley, R., Rich, M. S., Jorgensen, E. M.
10.64898/2026.01.15.699741 — Posted: 2026-01-15
NPEPPS segmental duplication drives position effect expression of TBC1D3 in the human brain
Guitart, X., Brunner, J. W., Ren, L., Jeong, H., Yoo, D., Porubsky, D., Vollger, M. R., Hoekzema, K., Munson, K. M., Sun, K., Ayllon, M., Hoglin, K., McMullen, R., Pavlovic, B., Pollen, A. A., Eichler, E. E.
10.64898/2026.01.14.699559 — Posted: 2026-01-15
The Drosophila proventriculus lacks stem cells but compensates for age-related cell loss via endoreplication-mediated cell growth
Ewen-Campen, B., Chen, W., Gopal Tattikota, S., Liu, Y., Hu, Y., Perrimon, N.
10.1101/2025.06.27.662004 — Posted: 2026-01-14
A single cluster of RNA Polymerase II molecules is stably associated with active genes
Mukherjee, A., Kapoor, M., Shankta, K., Fallacaro, S., Carter, R. D., Hayward-Lara, G., Ratchasanmuang, P., Haloush, Y. I., Mir, M.
10.1101/2025.02.10.637507 — Posted: 2026-01-14

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