Channel:  The Howard Hughes Medical Institute (HHMI)

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Wide Transition-State Ensemble as Key Component for Enzyme Catalysis
Jara, G. E., Pontiggia, F., Otten, R., Agafonov, R. V., Marti, M. A., Kern, D.
10.1101/2023.10.03.560706 — Posted: 2024-12-02
The molecular basis of integrated stress response silencing
Yang, Z., Haakonsen, D., Heider, M., Witus, S. R., Zelter, A., Beschauner, T., MacCoss, M. J., Rape, M.
10.1101/2024.12.02.626349 — Posted: 2024-12-02
TTF2 promotes replisome eviction from stalled forks in mitosis
Can, G., Shyian, M., Krishnamoorthy, A., Lim, Y., Wu, A., Zaher, M., Raeschle, M., Walter, J., Pellman, D.
10.1101/2024.11.30.626186 — Posted: 2024-11-30
Affinity maturation of antibody responses is mediated by differential plasma cell proliferation
MacLean, A. J., Deimel, L. P., Zhou, P., ElTanbouly, M. A., Merkenschlager, J., Ramos, V., Santos, G. S., Hagglof, T., Mayer, C. T., Hernandez, B., Gazumyan, A., Nussenzweig, M. C.
10.1101/2024.11.26.625430 — Posted: 2024-11-29
Reliable amplification of highly repetitive or low complexity sequence DNA enabled by superhelicase-mediated isothermal amplification
Kang, J., Rashid, F., Murray, P. J., Merino-Urteaga, R., Gavrilov, M., Shang, T., Jo, W., Ahmed, A., Aksel, T., Barrick, D., Berger, J. M., Ha, T.
10.1101/2024.11.27.625726 — Posted: 2024-11-29
Stereoselectivity of Aminoacyl-RNA Loop-closing Ligation
Kim, S., Todisco, M., Radakovic, A., Szostak, J. W.
10.1101/2024.11.26.625528 — Posted: 2024-11-28
An updated reference genome sequence and annotation reveals gene losses and gains underlying naked mole-rat biology
Sokolowski, D. J., Miclaus, M., Nater, A., Faykoo-Martinez, M., Hoekzema, K., Zuzarte, P., Monis, S., Alvi, S. A., Erdmann, J., Erdmann, A. L., Kumaragurubaran, R., Bayerl, J., Yoo, D., Karimpour, N., Ungerleider, K., Hou, H., Fergal, M., Hourlier, T., Clarke, Z. A., Lischer, H. E., Leordean, D. V., Jiang, Y., Pugh, T. J., Smith, E. S. J., Haggerty, L., Laird, D. J., Lilue, J., Holmes, M. M., Eichler, E. E., Bruggmann, R., Simpson, J. T., Balmus, G., Wilson, M. D.
10.1101/2024.11.26.625329 — Posted: 2024-11-28
Molecular patterns of evolutionary changes throughout the whole nervous system of multiple nematode species
Toker, I. A., Ripoll-Sanchez, L., Geiger, L. T., Saini, K. S., Beets, I., Vertes, P. E., Schafer, W. R., Ben-David, E., Hobert, O.
10.1101/2024.11.23.624988 — Posted: 2024-11-25
Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine
Hernandez, G., Osinski, A., Majumdar, A., Eitson, J. L., Antczak, M., Pawlowski, K., Niederstrasser, H., Servage, K. A., Posner, B., Schoggins, J. W., Ready, J. A., Tagliabracci, V. S.
10.1101/2024.11.22.624893 — Posted: 2024-11-25
Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping
Wang, K., Nie, Y., Maguire, C., Syphurs, C., Sheen, H., Karoly, M., Lapp, L., Gygi, J. P., Jayavelu, N. D., Patel, R. K., Hoch, A., IMPACC Network, , Corry, D., Kheradmand, F., McComsey, G. A., Fernandez-Sesma, A., Simon, V., Metcalf, J. P., Agudelo Higuita, N. I., Messer, W. B., David, M. M., Nadeau, K. C., Kraft, M., Bime, C., Schaenman, J., Erle, D., Calfee, C. S., Atkinson, M. A., Brackenridge, S. C., Hafler, D. A., Shaw, A. C., Rahman, A., Hough, C. L., Geng, L. N., Ozonoff, A., Haddad, E. K., Reed, E. F., Bakel, H. v., Kim-Schulze, S. H., Krammer, F., Wilson, M., Eckalbar, W., Bosinger
10.1101/2024.11.22.624784 — Posted: 2024-11-25

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