Channel:  The Howard Hughes Medical Institute (HHMI)

2,319 Articles

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Genome-scale functional mapping of the mammalian whole brain with in vivo Perturb-seq
Shi, T., Korshunova, M., Kim, S., DeTomaso, D., Zheng, X., Vishvanath, L., Nyasulu, T., Huynh, N., Sun, A., Thompson, P. C., Zhang, Y., Wigdor, E. M., Rohani, N., Ali, S., Qiu, H., Geralt, M., Zhao, Z., Rabhi, S., Yao, Z., van Velthoven, C. T., Nery, J. R., Castanon, R. G., Dicks, S., Chen, T. J., Ecker, J. R., Zeng, H., Zheng, G. X., Sanders, S. J., Sundaram, L., Jin, X.
10.64898/2026.03.16.711480 — Posted: 2026-03-18
Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures
Ahn, J. J., Yu, T. C., Dadonaite, B., Radford, C. E., Bloom, J. D.
10.64898/2026.01.05.697808 — Posted: 2026-03-18
Midgestation metabolic constraint in purine metabolism drives distinct strategies for placenta and fetal growth
Xu, W., De La Cruz, N., Woods, A., Lokshtanov, D., Gao, S., Khan, N. A., Wright, S., Florian-Rodriguez, M., McIntire, D. D., Duryea, E. L., Nelson, D. B., Spong, C. Y., Herrera, C. L., Hanna, J. H., Srivatsan, S. R., Aguilera Castrejon, A., Solmonson, A.
10.64898/2026.03.18.712680 — Posted: 2026-03-18
Heterotypic intercellular adhesion tunes efficiency of cell-on-cell migration
Kuyyamudi, C., Ghosh, S., Extavour, C. G.
10.1101/2025.08.29.673192 — Posted: 2026-03-18
Reconstituting Mouse Embryogenesis Ex Utero from Gastrulation to Fetal Development Reveals Maternally Independent Metabolic Programs
Lokshtanov, D., Gao, S. M., Xu, W., Kosman, A., Roncato, F., De La Cruz, N., Khan, N. A., Woods, A., Campbell, I., Woehler, A., Christoforou, C., Ding, L., Hu, A., Copeland, M., Wang, L., Yang, X., Raley, C., Delventhal, K., Herrera, A., Valente, A., Wright, S., Gomez-Cesar, E., Shlomo, R., Golenchenko, S., Oldak, B., Yilmaz, A., Gurhan-Sevinc, G., Comar, M.-Y., Viukov, S., Novershtern, N., Zhang, H., Duong, T., Li, L., Khatib, N., Kakun, R. R., Espinosa-Medina, I., Florian-Rodriguez, M. E., LaManno, G., Tillberg, P. W., Wang, M. C., Maza, I., Srivatsan, S., Solmonson, A., Hanna, J. H., Aguile
10.64898/2026.03.17.710314 — Posted: 2026-03-18
UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism
Nguyen, P. T., Wu, Z., Kim, D., Ogu, T., Yin, S., Sondhi, V., Cai, F., Tippetts, T. S., Jen, A., Shishkova, E. J., Cai, L., Dumesnil, D., Cervantes, M., Chen, H., Mishra, P., Coon, J., Hoxhaj, G., Ni, M., DeBerardinis, R. J.
10.64898/2026.03.18.712693 — Posted: 2026-03-18
Divergent C. elegans toxin alleles are suppressed by distinct mechanisms
Zdraljevic, S., Walter-McNeill, L., Bruni, G., Marquez, H., Collins, J., Leighton, D. H. W., Alexander, N., Bloom, J. S., Kruglyak, L.
10.1101/2024.04.26.591160 — Posted: 2026-03-18
In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles
Seraj, Z., Zottig, X., Huang, C., Loveland, A. B., Diggs, S., Sholi, E., Grigorieff, N., Korostelev, A. A.
10.1101/2025.11.25.690450 — Posted: 2026-03-17
A widespread electrical brain network encodes anxiety in health and depressive states
Hughes, D. N., Klein, M. H., Walder-Christensen, K. K., Thomas, G. E., Grossman, Y., Waters, D., Matthews, A. E., Carson, W. E., Filali, Y., Tsyglakova, M., Fink, A., Gallagher, N. M., Perez-Balaguer, M., McClung, C. A., Zarate, J. M., Hultman, R. C., Mague, S. D., Carlson, D., Dzirasa, K.
10.1101/2024.06.26.600900 — Posted: 2026-03-17
Statistical BURST imaging for high-fidelity biomolecular ultrasound
Lee, S., Shivaei, S., Shapiro, M. G.
10.64898/2026.03.13.711726 — Posted: 2026-03-17

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