Channel:  The Howard Hughes Medical Institute (HHMI)

2,121 Articles

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Characterizing the informativeness of pathogen genome sequence datasets about transmission between population groups
Tran-Kiem, C., Perofsky, A. C., Lessler, J., Bedford, T.
10.1101/2025.08.07.25333239 — Posted: 2025-12-18
Humanized Extracellular Vesicles for Efficient RNA Delivery
Ma, X., Zhao, S. R., Cepko, C. L.
10.64898/2025.12.15.694436 — Posted: 2025-12-17
Nanopore-based profiling of PEGylation in nucleic acid therapeutics
Patino Guillen, G., Schmidt, T. T., Baumberg, J. J., Szostak, J. W., Keyser, U. F., Boskovic, F.
10.64898/2025.12.15.694309 — Posted: 2025-12-17
Human acrocentric chromosome short arm de novo mutation and recombination
Lin, J., Mastrorosa, F. K., Noyes, M. D., Yoo, D., Rhie, A., Porubsky, D., Hoekzema, K., Munson, K. M., Koundinya, N., Watkins, W. S., Jorde, L. B., Quinlan, A. R., Neklason, D. W., Phillippy, A. M., Eichler, E. E.
10.64898/2025.12.16.694519 — Posted: 2025-12-17
Spatial gene expression maps in vertebrate limbs display conserved and regenerative species-specific features within connective tissue
McMann, C. L., Park, C., Cloutier, J. K., Reddien, P.
10.64898/2025.12.15.694399 — Posted: 2025-12-17
The Drosophila maternal-effect gene abnormal oocyte (ao) does not repress histone gene expression
Takenaka, R., Albanese, E. H., Simmerman, S. M., Verghese, S., Maddox, M. A. E., de la Cruz, A., Young, J. M., Schmidt, C. A., Rieder, L. E., Malik, H. S.
10.1101/2024.09.17.613536 — Posted: 2025-12-16
A signature-agnostic test for differences between tumor mutation spectra reveals carcinogen and ancestry effects
Hart, S. F. M., Alcala, N., Feder, A. F., Harris, K.
10.1101/2025.05.15.654154 — Posted: 2025-12-16
Neuroligin-2 is ubiquitinated by Nedd4l to control developmental astrocyte morphogenesis.
Sakers, K., Ramirez, J. J., Elazar, N., Nagendren, L., Soderblom, E. J., Eroglu, C.
10.64898/2025.12.15.694023 — Posted: 2025-12-16
Conserved phenotype and function of human brain border-associated macrophages in iPSC-derived models
Barr, H. J., Depp, C., Hingerl, M., Nguyen, T., Reimertz, J. M., Connolly, E., Patel, J., Doman, J. L., Marsh, S. E., Stevens, B.
10.64898/2025.12.11.693582 — Posted: 2025-12-14
Phosphatase SHP2 pathogenic mutations enhance activity by altering conformational sampling
Glaser, A., Padua, R., Ojoawo, A., Sullivan, C., Kern, D.
10.64898/2025.12.12.694068 — Posted: 2025-12-14

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