Channel:  The Howard Hughes Medical Institute (HHMI)

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Simulated climate change magnifies genetic vulnerabilities from mutation load and maladaptation
Leventhal, L., Ruffley, M. R., Carnegie Field Consortium, , Exposito-Alonso, M.
10.1101/2025.09.25.677362 — Posted: 2025-09-25
Regulation of Glypican 6-mediated Wnt activation maintains TDP-43 nuclear localization in neurons
Zhang, N., Sockanathan, S.
10.1101/2025.09.24.678385 — Posted: 2025-09-25
Dynamic changes in chromosome and nuclear architecture during maturation of normal and ALS C9orf72 motor neurons
Uyan, O., Sambare, S., Oomen, M. E., Wightman, N., Schooley, A., Klim, J. R., Belaghzal, H., Aydemir, O., Akgol-Oksuz, B., Uslu, Z. S. A., Eggan, K., Brown, R. H., Dekker, J.
10.1101/2025.09.22.677835 — Posted: 2025-09-23
CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via histone H1
Wang, S., Li, T., Naish, M., Chuang, R., Lin, E. K., Fonkalsrud, C., Yan, H., Feng, S., Henderson, I. R., Jacobsen, S. E.
10.1101/2025.09.22.677529 — Posted: 2025-09-22
Murine models for triple-negative breast cancer with differential responsiveness to immunotherapy
Kalantzakos, T., Zhou, Y., Liu, X., Proehl, J., Durfee, C., Tamayo, I., Temiz, N. A., Troness, B., Soni, A., Gupta, H., Harris, R.
10.1101/2025.09.18.677171 — Posted: 2025-09-21
Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits
Ruetten, V. M., Zheng, W., Siwanowicz, I. R., Mensh, B. D., Eddison, M., Hu, A., Chi, Y., Lemire, A. L., Guo, C., Kadobianskyi, M., Renz, M., Lelek-Greskovic, S., He, Y., Close, K., Ihrke, G., Dev, A., Petruncio, A., Wan, Y., Engert, F., Fishman, M. C., Judkewitz, B., Rubinov, M., Keller, P. J., Satou, C., Yu, G., Tillberg, P. W., Sahani, M., Ahrens, M. B.
10.1101/2025.08.20.670374 — Posted: 2025-09-20
Spatial predictive coding in visual cortical neurons
Zhang, Q., Grodem, S., Gracias, A., Lensjo, K. K., Fyhn, M., Stringer, C., Pachitariu, M.
10.1101/2025.09.17.676794 — Posted: 2025-09-19
RiboCop surveils pre-rRNA processing by Dicer in cellular quiescence
Roche, B., Martienssen, R. A.
10.1101/2025.09.16.676644 — Posted: 2025-09-18
FoxP3 forms a head-to-head dimer in vivo and stabilizes its multimerization on adjacent microsatellites
Leng, F., Clark, R., Zhang, W., Viennet, T., Arthanari, H., Wang, X., Hur, s.
10.1101/2025.09.16.676304 — Posted: 2025-09-18
PIEZO channels link mechanical forces to uterine contractions in parturition
Zhang, Y., Kini, S. A., Mishkanian, S. A., Luo, R., Seradj, S. H., Leung, V., Wang, Y., Rocio, S.-V. M., Keenan, W. T., Sonmez, U., Yarishkin, O., Sanchez-Alavez, M., Liu, Y., Jin, X., Lipomi, D. J., Li, Y., Petrascheck, M., Frolova, A. I., England, S. K., Patapoutian, A.
10.1101/2025.09.17.676899 — Posted: 2025-09-18

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