Channel:  The Howard Hughes Medical Institute (HHMI)

1,286 Articles

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Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine
Hernandez, G., Osinski, A., Majumdar, A., Eitson, J. L., Antczak, M., Pawlowski, K., Niederstrasser, H., Servage, K. A., Posner, B., Schoggins, J. W., Ready, J. A., Tagliabracci, V. S.
10.1101/2024.11.22.624893 — Posted: 2024-11-25
Whole-body simulation of realistic fruit fly locomotion with deep reinforcement learning
Vaxenburg, R., Siwanowicz, I., Merel, J., Robie, A. A., Morrow, C., Novati, G., Stefanidi, Z., Both, G.-J., Card, G. M., Reiser, M. B., Botvinick, M. M., Branson, K. M., Tassa, Y., Turaga, S. C.
10.1101/2024.03.11.584515 — Posted: 2024-11-22
Reconstitution of SPO11-dependent double-strand break formation
Zheng, Z., Zheng, L., Arter, M., Liu, K., Yamada, S., Ontoso, D., Kim, S., Keeney, S.
10.1101/2024.11.20.624382 — Posted: 2024-11-21
The transcription factor GABPA is a master regulator of naive pluripotency
Zhou, C., Wang, M., Zhang, C., Zhang, Y.
10.1101/2024.11.11.623003 — Posted: 2024-11-21
Cellular behavior analysis from live-cell imaging of TCR T cell-cancer cell interactions
Verma, A., Yu, C., Bachl, S., Lopez, I., Schwartz, M. S., Moen, E., Kale, N., Ching, C., Miller, G., Dougherty, T., Pao, E., Graf, W., Ward, C., Jena, S. G., Marson, A., Carnevale, J., Van Valen, D. A., Engelhardt, B. E.
10.1101/2024.11.19.624390 — Posted: 2024-11-21
Recurrent hyper-motif circuits in developmental programs
Adler, M., Medzhitov, R.
10.1101/2024.11.20.624466 — Posted: 2024-11-20
Divergent C. elegans toxin alleles are suppressed by distinct mechanisms
Zdraljevic, S., Walter-McNeill, L., Bruni, G., Marquez, H., Collins, J., Leighton, D. H. W., Alexander, N., Bloom, J. S., Kruglyak, L.
10.1101/2024.04.26.591160 — Posted: 2024-11-20
Improved protein binder design using -pairing targeted RFdiffusion
Sappington, I., Toul, M., Lee, D. S., Robinson, S. A., Goreshnik, I., McCurdy, C., Chan, T. C., Buchholz, N., Huang, B., Vafeados, D., Roullier, N., Garcia-Sanchez, M., Glögl, M., Kim, C., Watson, J. L., Torres, S. V., Verschueren, K. H. G., Verstraete, K., Hinck, C. S., Bernard-Valle, M., Coventry, B., Sims, J. N., Ahn, G., Wang, X., Hinck, A. P., Jenkins, T. P., Ruohola-Baker, H., Banik, S., Savvides, S. N., Baker, D.
10.1101/2024.10.11.617496 — Posted: 2024-11-19
ELAVL3 regulates splicing of RNAs encoding synaptic signaling proteins in D1 and D2 striatal medium spiny neurons.
Irmady, K., Scheckel, C., Singer, R. A., Carroll, T., Darnell, R. B.
10.1101/2024.11.18.622571 — Posted: 2024-11-19
A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation
Wang, Y., Zhang, Y., Leung, V., Heydari-Seradj, S., Sonmez, U., Servin-Vences, R., Lipomi, D. J., Ye, L., Patapoutian, A.
10.1101/2024.11.18.624210 — Posted: 2024-11-19

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