Channel:  The Howard Hughes Medical Institute (HHMI)

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Mechanism of age-related accumulation of mitochondrial DNA mutations in human blood
Gupta, R., Durham, T. J., Chau, G., Uddin, M. M., Lu, W., Karczewski, K. J., Howrigan, D., Natarajan, P., Zhou, W., Neale, B. M., Mootha, V. K.
10.1101/2025.05.25.655566 — Posted: 2025-05-28
Chemical capture of diazo metabolites reveals biosynthetic hydrazone oxidation
Pfeifer, K., Van Cura, D., Wu, K. J. Y., Balskus, E. P.
10.1101/2025.05.24.655970 — Posted: 2025-05-28
Rapid adaptation and extinction across climates in synchronized outdoor evolution experiments of Arabidopsis thaliana
Wu, X., Bellagio, T., Peng, Y., Czech, L., Lin, M., Lang, P., Epstein, R., Abdelaziz, M., Alexander, J., Caton-Darby, M., Alonso-Blanco, C., Andersen, H. L., Berbel, M., Bergelson, J., Burghardt, L., Delker, C., Dimitrakopoulos, P. G., Donohue, K., Durka, W., Escribano-Avila, G., Franks, S. J., Fritschi, F. B., Galanidis, A., Garcia-Fernandez, A., Garcia-Munoz, A., Hamann, E., Herber, M., Hutt, A., Iriondo, J. M., Juenger, T. E., Keller, S., Koehl, K., Korte, A., Korte, P., Kuschera, A., Lara-Romero, C., Leventhal, L., Maag, D., Marcer, A., March-Salas, M., Meaux, J. d., Mendez-Vigo, B., Moren
10.1101/2025.05.28.654549 — Posted: 2025-05-28
A new heme enzyme family forms hydrazine groups in diverse biosynthetic pathways
Kenney, G. E., Wang, K.-K. A., Ng, T., van der Donk, W., Balskus, E. P.
10.1101/2025.05.27.656397 — Posted: 2025-05-27
Prevalence of Group II Introns in Phage Genomes
Merk, L. N., Jones, T. A., Eddy, S. R.
10.1101/2025.05.22.655115 — Posted: 2025-05-23
Endosome transcriptomics reveal trafficking of Cajal bodies into multivesicular bodies
Singh, J., Williams, J. K., Elliott, Q., Jhawar, R., Ferguson, L., Collins, K., Schekman, R.
10.1101/2025.05.22.655499 — Posted: 2025-05-22
Archaeal SegAB forms a bipolar structure that promotes chromosome segregation in spherical cells
Charles-Orszag, A., Lord, S. J., Herrera, N., Strauskulage, L., Bhowmick, A., Goddard, T., Wassmer, B., van Wolferen, M., Asper, G., Flis, A., Rodriguez, J., Redding, S., Rosenberg, O., Albers, S.-V., Mullins, D.
10.1101/2025.04.15.649018 — Posted: 2025-05-21
Characterization of a novel glycocin from a thermophile
Martini, R. M., van der Donk, W.
10.1101/2025.05.19.655019 — Posted: 2025-05-20
The inactive X chromosome drives sex differences in microglial inflammatory activity in human glioblastoma
Tharp, M. E., Han, C. Z., Talukdar, M., Balak, C. D., Fitzpatrick, C., O'Connor, C., Preissl, S., Buchanan, J., Nott, A., Escoubet, L., Mavrommatis, K., Gupta, M., Schwartz, M. S., U, H. S., Jones, P. S., Levy, M. L., Gonda, D. D., Ben-Haim, S., Ciacci, J., Barba, D., Khalessi, A., Coufal, N. G., Chen, C. C., Glass, C. K., Page, D. C.
10.1101/2024.06.06.597433 — Posted: 2025-05-19
Thrifty wide-context models of B cell receptor somatic hypermutation
Sung, K., Johnson, M. M., Dumm, W., Simon, N., Haddox, H., Fukuyama, J., Matsen, F. A.
10.1101/2024.11.26.625407 — Posted: 2025-05-19

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