Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

335 Articles

α-Synuclein Overexpression and the Microbiome Shape the Gut and Brain Metabolome in Mice
Morais, L. H., Boktor, J. C., MahmoudianDehkordi, S., Kaddurah-Daouk, R., Mazmanian, S. K.
10.1101/2024.06.07.597975 — Posted: 2024-06-10
Impaired Functional Connectivity of Cortico-Amygdala Pathway Can Drive Social Behavior Deficits in Synucleinopathies
Zhou, W., Daniels, S., Singh, V., Menard, M., Galvis, M. E., Chu, H.-Y.
10.1101/2024.05.20.594995 — Posted: 2024-06-10
Internalized α-synuclein fibrils become truncated and resist degradation in neurons while glial cells rapidly degrade α-synuclein fibrils.
Karim, M. R., GAsparini, E., Tiegs, E., Schlichte, R., Vermilyea, S. C., Lee, M. K.
10.1101/2024.06.05.597615 — Posted: 2024-06-08
Lysosome damage triggers acute formation of ER to lysosomes membrane tethers mediated by the bridge-like lipid transport protein VPS13C
Wang, X., Xu, P., Bentley-DeSousa, A., Hancock-Cerutti, W., Cai, S., Johnson, B. T., Tonelli, F., Talaia, G., Alessi, D. R., Ferguson, S. M., De Camilli, P.
10.1101/2024.06.08.598070 — Posted: 2024-06-08
LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons
Chen, C., Masotti, M., Shepard, N., Promes, V., Tombesi, G., Arango, D., Manzoni, C., Greggio, E., Hilfiker, S., Kozorovitskiy, Y., Parisiadou, L.
10.1101/2024.06.06.597594 — Posted: 2024-06-08
Refinement of efficient encodings of movement in the dorsolateral striatum throughout learning
Jaidar, O., Albarran, E., Albarran, E., Wu, Y.-W., Ding, J. B.
10.1101/2024.06.06.596654 — Posted: 2024-06-06
A staged screening protocol identifies people with biomarkers related to neuronal alpha-synuclein disease
Brown, E. G., Chahine, L. M., Siderowf, A., Gochanour, C., Kurth, R., Marshall, M. J., Caspell-Garcia, C., Brumm, M. C., Coffey, C. S., Stanley, C. E., Korell, M., McMahon, B., Kuhl, M., Fabrizio, K., Heathers, L., Foroud, T. M., Concha-Marambio, L., Soto, C., Chowdhury, S., Simuni, T., Marek, K., Tanner, C. M., the Parkinson's Progression Markers Initiative
10.1101/2024.06.03.24308229 — Posted: 2024-06-04
Genetic screening and metabolomics identify glial adenosine metabolism as a therapeutic target in Parkinson's disease
Sodders, M. J., Avila-Pacheco, J., Okorie, E. C., Shen, M., Kumari, N., Marathi, A., Lakhani, M., Bullock, K., Pierce, K., Dennis, C., Jeanfavre, S., Sarkar, S., Scherzer, C. R., Clish, C., Olsen, A. L.
10.1101/2024.05.15.594309 — Posted: 2024-06-02
The diversity of SNCA transcripts in neurons, and its impact on antisense oligonucleotide therapeutics
Evans, J. R., Gustavsson, E. K., Doykov, I., Murphy, D., Virdi, G., Lachica, J., Rontgen, A., Murtada, M. H., Pang, C. W., Macpherson, H., Wernick, A. I., Toomey, C. E., Athauda, D., Choi, M., Hardy, J., Wood, N. W., Vendruscolo, M., Mills, K., Heywood, W., Ryten, M., Gandhi, S.
10.1101/2024.05.30.596437 — Posted: 2024-05-31
Microbiome-based biomarkers to guide personalized microbiome-based therapies for Parkinson's disease
Payami, H., Sampson, T. R., Murchison, C. F., Wallen, Z. D.
10.1101/2024.04.03.24305273 — Posted: 2024-05-30

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