Channel:  Aligning Science Across Parkinson's (ASAP)

459 Articles

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The age at onset of LRRK2 p.Gly2019Ser Parkinson's disease across ancestries and countries of origin
Lüth, T., Laabs, B.-H., Sendel, S., König, I. R., Caliebe, A., Noyce, A. J., Screven, L. A., Bardien, S., Farrer, M., Hentati, F., Klein, C., Ben Sassi, S., Trinh, J., Global Parkinson's Genetics Program (GP2)
10.1101/2025.06.04.25327685 — Posted: 2025-06-09
JIP4 deficiency causes a novel lysosome storage disease arising from impaired cystine efflux
Nassar, L. M., Shi, x., Roczniak-Ferguson, A., Shen, H., Ferguson, S. M.
10.1101/2025.06.06.657909 — Posted: 2025-06-09
Genetic modulation of immune gene co-expression in the aged mouse hippocampus by the Apbb1ip locus
Tomkins, J. E., Methi, A., Bouland, G., Doludda, B., Murphy, K., Miller, J. A., Overall, R. W., Mozhui, K.
10.1101/2025.06.04.657838 — Posted: 2025-06-08
Parkinson's disease-vulnerable and -resilient dopamine neurons display opposite responses to excitatory input
Hadjas, L. C., Kollman, G. J., Linderhof, L., Xia, M., Mansur, S., Saint-Pierre, M., Lim, B., Lee, E. B., Cicchetti, F., Awatramani, R., Hollon, N. G., Hnasko, T. S.
10.1101/2025.06.03.657460 — Posted: 2025-06-07
Bridging Pleiotropic Mechanisms in Leprosy Type-1 Reactions and Neurodegenerative diseases
Fava, V. M., Perico, J., Orlova, M., Dallmann-Sauer, M., Xu, Y. Z., Van Thuc, N., Thai, V. H., Belone, A. F., Latini, A. C. P., Schurr, E.
10.1101/2025.06.05.25329059 — Posted: 2025-06-06
RAB32-linked Parkinson's disease: Deep phenotyping, MDSGene literature review, and application of SynNeurGe criteria
Kleinz, T., Cavallieri, F., Borsche, M., Toschi, G., Valzania, F., Fioravanti, V., Valente, E. M., Mitrotti, P., Avenali, M., Zittel, S., Born, R., Matarazzo, M., Di Fonzo, A., Monfrini, E., Radefeldt, M., Santinelli, L., Griebner, N., Shambetova, C., Brand, M., Gabbert, C., Blauwendraat, C., Trinh, J., Beetz, C., Bauer, P., Brueggemann, N., Global Parkinson's Genetics Program (GP2), , Klein, C.
10.1101/2025.06.03.25328628 — Posted: 2025-06-03
Genetically Encoded and Modular SubCellular Organelle Probes (GEM-SCOPe) reveal lysosomal and mitochondrial dysfunction driven by PRKN knockout
Goldman, C., Kareva, T., Sarrafha, L., Sahasrabudhe, A., Schuldt, B. R., Ahfeldt, T., Blanchard, J. W.
10.1101/2024.05.21.594886 — Posted: 2025-06-02
Cortical synaptic vulnerabilities revealed in a α-synuclein aggregation model of Parkinson's disease
Sah, S., Sauerbeck, A. D., Gupta, J., Perez-Acuna, D., Reiber, J. E., Russell, D., Goralski, T., Henderson, M., Volpicelli-Daley, L. A., Higley, M. J., Kummer, T. T., Biederer, T.
10.1101/2024.06.20.599774 — Posted: 2025-05-31
Movement-related activity in the internal globus pallidus of the parkinsonian macaque
Kase, D., Zimnik, A. J., Han, Y., Harsch, D. R., Bacha, S., Cox, K. M., Bostan, A. C., Richardson, R. M., Turner, R. S.
10.1101/2024.08.29.610310 — Posted: 2025-05-30
Sex-dimorphic effects of neuromelanin buildup in rodent nigral dopamine neurons: implications for sex-biased vulnerability in Parkinson's disease
D'Addario, S. L., Massaro Cenere, M., Cossa, F., Scaricamazza, S., Nesci, V., D'Ottavio, G., Caprioli, D., Ferri, A., Vila, M., Ledonne, A., Mercuri, N. B.
10.1101/2025.04.18.649338 — Posted: 2025-05-27

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