Channel:  Aligning Science Across Parkinson's (ASAP)

460 Articles

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Genome-wide association analyses reveal susceptibility variants linked to Parkinson's disease in the South African population using inferred global and local ancestry
Step, K., Leal, T. P., Waldo, E., Madula, L., Swart, Y., Hernandez, C. F., Kim, J. J., Bandres Ciga, S., Global Parkinson's Genetics Program, , Mata, I., Bardien, S.
10.1101/2025.08.01.25331910 — Posted: 2025-08-02
Elevated brain α-synuclein, phosphorylated-tau, and oxidative stress in mice that survived influenza A pneumonitis
Lunn, M. O., Lengacher, N. A., Hake-Volling, Q., Tomlinson, J. J., aSCENT-PD Investigators, , Brown, E. G., Schlossmacher, M. G.
10.1101/2025.07.31.667659 — Posted: 2025-08-01
LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson's disease model
Blasco-Agell, L., Espinal, M. P., Testa, V., Roch, G., Montero-Mu, J., Fern, I., Baruffi, V., Gonzalez-Sepulveda, M., Richaud-Patin, Y., Jim, S., Cuadros, T., Cladera-Sastre, J. M., Compte, J., Manglano-Artu"n"edo, Z., Ventura, S., Otero, M. J., Tolosa, E., Raya, A., Vila, M., Consiglio, A.
10.1101/2024.10.07.616997 — Posted: 2025-07-30
CNV-Finder: Streamlining Copy Number Variation Discovery
Kuznetsov, N., Daida, K., Makarious, M. B., Al-Mubarak, B., Atterling Brolin, K., Malik, L., Kouam, C., Baker, B., Real, R., Step, K., Lange, L. M., Wu, L., Ostrozovicova, M., Andersh, K. M., Kung, P.-J., Mecheri, Y., Tay, Y.-W., Soundous Malek, B., Al Tassan, N., Teresa Perinan, M., Hong, S., Koretsky, M. J., Sargeant, L., Levine, K., Blauwendraat, C., Billingsley, K. J., Bandres-Ciga, S., Leonard, H. L., Bardien, S., Morris, H. R., Singleton, A. B., Nalls, M. A., Vitale, D., The Global Parkinson's Genetics Program
10.1101/2024.11.22.624040 — Posted: 2025-07-26
Sex-stratified analysis of the potential association between PGLYRP2 rs892145 variant and Parkinson's disease across diverse ancestral populations
Avila, C. L., Chaparro Solano, H. M., Quintana-Pena, V., Aberg, K., the Global Parkinson's Genetics Program (GP2), , Atterling Brolin, K.
10.1101/2025.07.23.25331993 — Posted: 2025-07-24
DIO-SPOTlight Transgenic Mouse to Functionally Monitor Protein Synthesis Regulated by the Integrated Stress Response
Oliver, M. L., Caffall, Z. F., Eatman, C. B., Faw, T. D., Calakos, N.
10.1101/2024.10.14.618312 — Posted: 2025-07-23
Enhanced beta power emerges from simulated parkinsonian primary motorcortex
Doherty, D. W., Chen, L., Smith, Y., Wichmann, T., Chu, H.-Y., Lytton, W. W.
10.1101/2024.05.23.595566 — Posted: 2025-07-20
Genotype-phenotype association study conducted on LARGE-PD reveals novel loci associated with Parkinson's Disease.
Leal, T. P., Waldo, E., Duarte-Zambrano, F., Inca-Martinez, M., Ramchandra, J., Chaparro-Solano, H. M., Anello, A. E., Borda, V., Gouveia, M. H., Teixeira-dos-Santos, D., Reyes-Perez, P., Gatto, E. M., Santos-Lobato, B. L., Eufraseo, G., Letro, G. H., Arboleda, G., Bernal-Pacheco, O., Orozco, J., Munoz, B., Chana-Cuevas, P., Aguillon, D., Moreno, S., Torrealba-Acosta, G., Lobo-Prada, T., Muller, V., Lopez Razquin, C. M., Braga-Neto, P., Duron, R., Rodriguez-Violante, M., Hernandez-Medrano, A. J., Cervantes-Arriaga, A., Martinez-Ramirez, D., Schuh, A. F. S., de Mello Rieder, C. R., Cornejo-Oliv
10.1101/2025.07.18.25331793 — Posted: 2025-07-18
Mapping the causal chain from genetic risk variants to lipid dysmetabolism in Parkinsons disease
DePaula, R., Kim, J., Rhinn, H., Saade, H., Chavez, F., Segura, T., Lozano, M. V., Etoundi, M., Silos, K., Korchina, V., doddapaneni, h. v., Venner, E., Masdeu, J. C., Pavlik, V., Yu, M. M., Lin, C.-Y. R., Jankovic, J., Buchman, A. S., Muzny, D. M., Gibbs, R. A., Elsea, S. H., Abeliovich, A., Lansbury, P., Vanegas-Arroyave, N., Shaw, C. A., Shulman, J. M.
10.1101/2025.07.14.25331535 — Posted: 2025-07-15
The Global Landscape of Genetic Variation in Parkinson's disease: Multi-Ancestry Insights into Established Disease Genes and their Translational Relevance
Lange, L. M., Fang, Z.-H., Makarious, M. B., Kuznetsov, N., Atterling Brolin, K., Ballard, S., Bardien, S., Doquenia, M. L., Heutink, P., Houlden, H., Iwaki, H., Jasaityte, S., Jones, L., Junker, J., Kaiyrzhanov, R., Koretsky, M., Kumar, K. R., the Latin American Research Consortium on the Genetics of Parkinson's Disease (LARGE-PD), , Leonard, H., Levine, K., Lim, S.-Y., Mencacci, N. E., Mohamed, W. M. Y., Nalls, M. A., Noyce, A., Ojha, R., Okubadejo, N. U., Rehman, S. u., Screven, L., Shashkin, C., Sopromadze, S., Stafford, E. J., Tan, A. H., Tan, M., Tavadyan, Z., Trinh, J., Tserensodnom, B
10.1101/2025.07.08.25330815 — Posted: 2025-07-11

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