Channel:  Aligning Science Across Parkinson's (ASAP)

451 Articles

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Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2
Chen, S., Basiashvili, T., Hutchings, J., Murillo, M. S., Suarez, A. V., Xiong, E., Louro, J. A., Leschziner, A. E., Villa, E.
10.1101/2024.06.18.599606 — Posted: 2025-07-10
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex
Salazar, M. P. R., Kolanukuduru, S., Ramirez, V., Lyu, B., Manigault, G., Sejourne, G., Sesaki, H., Yu, G., Eroglu, C.
10.1101/2024.10.22.619706 — Posted: 2025-07-03
EVscope: A Comprehensive Bioinformatics Pipeline for Accurate and Robust Analysis of Total RNA Sequencing from Extracellular Vesicles
Zhao, Y., Chintalapudi, H., Xu, Z., Liu, W., Hu, Y., Grassin, E., Song, M., Hong, S., Lee, L. P., Dong, X.
10.1101/2025.06.24.660984 — Posted: 2025-06-27
TX2P: A Proteogenomic Tool for Comprehensive Transcript Analysis
Murphy, D., Wood, N. W., Ryten, M., Gustavsson, E. K.
10.1101/2025.06.24.661260 — Posted: 2025-06-27
Bidirectional regulation of glycoprotein nonmetastatic melanoma protein B by β-glucocerebrosidase deficiency in GBA1 isogenic dopaminergic neurons from a patient with Gaucher disease and parkinsonism
Chen, C., Ma, C., Sam, R., Lichtenberg, J., Chen, T., Hao, Y., Li, Z., Kowal, I., Andersh, K., Qi, Y. A., Perez, G., Hertz, E., Li, Y., Williams, D., Henderson, M. J., Park, M., Jiang, X., Jerez, P. A., Blauwendraat, C., Sidransky, E., Chen, Y.
10.1101/2025.06.23.661126 — Posted: 2025-06-25
Characterizing Parkinson's Disease Clinical and Biomarker Interactions in REM Sleep Behavior Disorder
Reddy, V. L., Esposito, S., Renkl, E., Benyakoub, A., Mead, K., Chrysostoum, C., Patel, S., Seibyl, J. P., Huang, Y., Koo, B. B., Cedarbaum, J. M.
10.1101/2025.05.16.25327469 — Posted: 2025-06-23
Development of a protocol utilizing single-cell analysis for the differentiation of human iPSCs into SOX6+ midbrain dopaminergic neurons.
Lyu, G., Garcia Swinburn, R., Kreutzmann, J. C., Xiong, A., Kojima, R., Abaurre, C., Tremolanti, C., Gellhaar, S., Uhlen, P., Svenningsson, P., Castelo Branco, G., Dagliyan, O., Salto, C., Arenas, E.
10.1101/2025.06.18.660098 — Posted: 2025-06-22
Sub-second analysis of locomotor activity in Parkinsonian mice
Berezhnoi, D., Chehade, H. D., Simms, G., Chen, L., SIVANVAYAL NARASIMHAN, K. K., Dravid, S., Chu, H.-Y.
10.1101/2024.12.26.630411 — Posted: 2025-06-18
Generation of knock-in Cre and FlpO mouse lines for precise targeting of striatal projection neurons and dopaminergic neurons
Albarran, E., Fushiki, A., Nelson, A., Ng, D., Chaimowitz, C., Nikoobakht, L., Sippy, T., Peterka, D. S., Costa, R. M.
10.1101/2025.06.15.659794 — Posted: 2025-06-15
Single-cell multiomics identifies both shared and unique features of immune dysfunction in Parkinson's disease and inflammatory bowel disease colon, plasma and stool
Bolen, M. L., Buendia, M., Shi, J., Staley, H., Kachergus, J. M., Efron, P. A., Park, G., Nagpal, R., Alvarez, S. D., Xue, Q.-S., McFarland, N. R., Zimmermann, E. M., Forsmark, C. E., Menees, K. B., Salas, A., Thompson, E. A., Tansey, M. G.
10.1101/2025.04.29.651228 — Posted: 2025-06-11

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