Channel:  Aligning Science Across Parkinson's (ASAP)

392 Articles

End-product inhibition of the LRRK2-counteracting PPM1H phosphatase
Adhikari, A., Tripathi, A., Chiang, C. Y., Sherpa, P. L., Pfeffer, S. R.
10.1101/2025.05.16.654599 — Posted: 2025-05-17
Introducing PIGMO, a novel PIGmented MOuse model of Parkinson's disease (V2)
Chocarro, J., Marana, S., Espelosin, M., Rico, A. J., Ariznabarreta, G., Lorenzo-Ramos, E., Ilarduya, M. M., Hernandez-Alcoceba, R., Chillon, M., Vila, M., Kordower, J., Schapira, A. H. V., Garcia-Osta, A., Cuadrado-Tejedor, M., Lanciego, J. L.
10.1101/2025.05.09.653000 — Posted: 2025-05-15
Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice
Xu, P., Mancuso, R. I., Leonzino, M., Zeiss, C. J., Krause, D. S., De Camilli, P.
10.1101/2025.05.09.653147 — Posted: 2025-05-13
Safety and Feasibility of Serial Lumbar Punctures: Long-term Results from the Parkinson's Progression Markers Initiative
Barbosa, W., Schneider, R. B., Choi, S. H., Marshall, M. J., Lafontant, D.-E., Caspell-Garcia, C., Coffey, C. S., Ross, J., Siderowf, A., Marek, K., Simuni, T., on behalf of The Parkinson's Progression Markers Initiative (PPMI)
10.1101/2025.05.05.25327008 — Posted: 2025-05-06
Assessment of common genetic variation in Alzheimer's and Parkinson's diseases reveals global distinction in population attributable risk
Jones, L., Cerquera-Cleves, C., Schumacher-Schuh, A. F., Makarious, M. B., Iwaki, H., Nalls, M. A., Noyce, A., Global Parkinson's Genetics Program (GP2), , Blauwendraat, C., Singleton, A., Mata, I., Cookson, M. R., Bandres-Ciga, S.
10.1101/2024.09.23.24314240 — Posted: 2025-05-05
PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation
Wang, S., Baumert, R., Sejourne, G., Sivadasan Bindu, D., Dimond, K., Sakers, K., Vazquez, L., Moore, J. L., Tan, C. X., Takano, T., Rodriguez, M. P., Brose, N., Bradley, L., Lessing, R., Soderling, S. H., La Spada, A. R., Eroglu, C.
10.1101/2023.04.09.536178 — Posted: 2025-04-29
T cell responses towards PINK1 and α-synuclein are elevated in prodromal Parkinson's disease
Johansson, E., Freuchet, A., Williams, G. P., Michealis, T., Frazier, A., Litvan, I., Goldman, J. G., Alcalay, R. N., Standaert, D. G., Amara, A. W., Stover, N., Fon, E. A., Postuma, R. B., Sidney, J., Sulzer, D., Lindestam Arlehamn, C. S., Sette, A.
10.1101/2025.04.21.649871 — Posted: 2025-04-24
Differential memory enrichment of cytotoxic CD4 T cells in Parkinson's disease patients reactive to α-synuclein
Freuchet, A., Johansson, E., Frazier, A., Litvan, I., Goldman, J. G., Alcalay, R. N., Sulzer, D., Lindestam Arlehamn, C. S., Sette, A.
10.1101/2025.04.21.649867 — Posted: 2025-04-24
Sex-dimorphic effects of neuromelanin buildup in rodent nigral dopamine neurons: implications for sex-biased vulnerability in Parkinson's disease
D'Addario, S. L., Massaro Cenere, M., Cossa, F., Scaricamazza, S., Nesci, V., D'Ottavio, G., Caprioli, D., Ferri, A., Vila, M., Ledonne, A., Mercuri, N. B.
10.1101/2025.04.18.649338 — Posted: 2025-04-23
ATG2A engages Rab1a and ARFGAP1 positive membranes during autophagosome biogenesis
Fuller, D. M., Wu, Y., Schueder, F., Rasool, B., Nag, S., Korfhage, J. L., Garcia-Milian, R., Melnyk, K. D., Bewersdorf, J., De Camilli, P., Melia, T.
10.1101/2025.03.24.645038 — Posted: 2025-04-17

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