Channel:  Aligning Science Across Parkinson's (ASAP)

500 Articles

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LRRK2 mutations block NCOA4 trafficking upon iron overload leading to ferroptotic death
Goldman, A., Nguyen, M., Lanoix, J., Li, C., Fahmy, A., Zhong Xu, Y., Schurr, E., Thibault, P., Desjardins, M., McBride, H.
10.1101/2025.08.25.672135 — Posted: 2026-04-17
Astrocytes mediate the dopaminergic modulation of tonic GABAergic signaling in substantia nigra
Simmons, D. V., Moreno-Ramos, O. A., Raj, D. D. A., Kaganovsky, K., Pamukcu, A., Vrieler, N., Tkatch, T., Xie, Z., Zampese, E., De Sousa, A. I. S., Ding, J., Awatramani, R. V., Wilson, C., Surmeier, D. J.
10.1101/2024.03.27.586699 — Posted: 2026-04-17
Modeling cis-regulatory variation in human brain enhancers across a large Parkinson's Disease cohort
Sigalova, O. M., Pancikova, A., De Man, J., Theunis, K., Hulselmans, G. J., Konstantakos, V., Stuyven, B., De Brabandere, A., Geurts, J., Mikorska, A., Mukherjee, S., Abouelasrar Salama, S., Vandereyken, K., Davie, K., Mahieu, L., Adler, C. H., Beach, T. G., Serrano, G. E., Voet, T., Demeulemeester, J., Aerts, S.
10.64898/2026.03.15.711881 — Posted: 2026-04-16
Myeloid-Driven Inflammation in Prodromal Parkinson's Disease
Yasumizu, Y., Deerhake, M. E., Moon, J., Buitrago-Pocasangre, N., Russo, A., Wang, H., Zhu, B., Seibyl, J. P., Reddy, V., Wang, Q., Neish, K. J., Spillantini, M. G., Posner, D. A., Clatworthy, M., Sumida, T. S., Longbrake, E. E., Cedarbaum, J. M., Zhang, L., Hafler, D. A.
10.1101/2025.05.16.654530 — Posted: 2026-04-14
Striatal ensembles specify and control granular forelimb actions
Rodrigues-Vaz, I., Athalye, V. R., Peterka, D. S., Costa, R. M.
10.64898/2025.12.03.692128 — Posted: 2026-04-14
GPNMB and glycosphingolipid measurements in cerebrospinal fluid and plasma from Parkinson's disease patients in the BioFind cohort
Fernandez-Suarez, M. E., Bush, R. J., Di Biase, E., Te Vruchte, D., Priestman, D., Cortina-Borja, M., Cooper, O., Hardy, J., Hallett, P., Isacson, O., Platt, F. M.
10.64898/2026.04.09.712000 — Posted: 2026-04-13
ATP13A2 Loss of Function-Driven Polyamine Dysregulation Induces SAM Depletion and Epigenetic Astrocyte Toxicity
Coccia, E., Morrone Parfitt, G., Ijaz, S., Sati, A., Gesner, J., Perez Arevalo, A., Strong, J., Bright, A., Sohail, S., Meimoun, T., Ahfeldt, T., Vangheluwe, P., Blanchard, J.
10.64898/2026.04.02.716164 — Posted: 2026-04-06
Neural cell state modulation by PARK2 and dopaminergic neuroprotection by small molecule Parkin agonism
Gong, Y., Bayati, A., Alban, T. J., Parthasarathy, P., Zhou, F., Makarov, V., Zhao, Y., Su, C., Schumacher, J. G., Singh, V., Volpicelli-Daley, L. A., Luo, W., Durcan, T. M., Dutta, S., Schwarzschild, M. A., Johnston, J. A., Chan, T. A., Chen, X.
10.64898/2026.04.01.715918 — Posted: 2026-04-04
Utilizing Intraindividual Cognitive Variability to Predict Early Neuronal Synuclein Disease Progression
Combs, H. L., Kurth, R., Nair, A., York, M. K., Weintraub, D., Lafontant, D.-E., Caspell-Garcia, C., and the Parkinson's Progression Markers Initiative
10.1101/2025.10.21.25338482 — Posted: 2026-03-31
Rise-and-fall dynamics reveal a molecular and cellular vulnerability axis in prion-like α-synuclein propagation
Alexandersen, C. G., Brynildsen, J. K., Prigent, A., Tamborrino, M., Mantziou, A., Kurgat, K., Henderson, M. X., Bassett, D. S.
10.64898/2026.03.27.714785 — Posted: 2026-03-31

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