Channel:  Aligning Science Across Parkinson's (ASAP)

514 Articles

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Rare but Relevant: Assessing Variants in Dystonia-linked Genes in Parkinson's Disease
Lange, L. M., Fang, Z.-H., Screven, L., Tan, A. H., Alcalay, R. N., Amouri, R., Bovenzi, R., Fenn, M., Frost, J. L. I., Jankovic, J., Jasaityte, S., Jaunmuktane, Z., Jeon, B., Keller Sarmiento, I. J., Krueger, R., Kuhlenbaeumer, G., Lin, C.-H., Pavelka, L., Perinan, M. T. M., Ben Sassi, S., Schirinzi, T., Shin, J. H., Shulman, J. M., Tay, Y. W., Uitti, R., Warner, T., Wszolek, Z. K., Wu, L., Wu, R.-M., Zeuner, K. E., Blauwendraat, C., Singleton, A., Mencacci, N. E., Morris, H., Lim, S.-Y., Lohmann, K., Klein, C., the Global Parkinson's Genetics Program (GP2)
10.1101/2025.07.10.25330831 — Posted: 2025-07-11
Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2
Chen, S., Basiashvili, T., Hutchings, J., Murillo, M. S., Suarez, A. V., Xiong, E., Louro, J. A., Leschziner, A. E., Villa, E.
10.1101/2024.06.18.599606 — Posted: 2025-07-10
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex
Salazar, M. P. R., Kolanukuduru, S., Ramirez, V., Lyu, B., Manigault, G., Sejourne, G., Sesaki, H., Yu, G., Eroglu, C.
10.1101/2024.10.22.619706 — Posted: 2025-07-03
TX2P: A Proteogenomic Tool for Comprehensive Transcript Analysis
Murphy, D., Wood, N. W., Ryten, M., Gustavsson, E. K.
10.1101/2025.06.24.661260 — Posted: 2025-06-27
EVscope: A Comprehensive Bioinformatics Pipeline for Accurate and Robust Analysis of Total RNA Sequencing from Extracellular Vesicles
Zhao, Y., Chintalapudi, H., Xu, Z., Liu, W., Hu, Y., Grassin, E., Song, M., Hong, S., Lee, L. P., Dong, X.
10.1101/2025.06.24.660984 — Posted: 2025-06-27
Bidirectional regulation of glycoprotein nonmetastatic melanoma protein B by β-glucocerebrosidase deficiency in GBA1 isogenic dopaminergic neurons from a patient with Gaucher disease and parkinsonism
Chen, C., Ma, C., Sam, R., Lichtenberg, J., Chen, T., Hao, Y., Li, Z., Kowal, I., Andersh, K., Qi, Y. A., Perez, G., Hertz, E., Li, Y., Williams, D., Henderson, M. J., Park, M., Jiang, X., Jerez, P. A., Blauwendraat, C., Sidransky, E., Chen, Y.
10.1101/2025.06.23.661126 — Posted: 2025-06-25
Characterizing Parkinson's Disease Clinical and Biomarker Interactions in REM Sleep Behavior Disorder
Reddy, V. L., Esposito, S., Renkl, E., Benyakoub, A., Mead, K., Chrysostoum, C., Patel, S., Seibyl, J. P., Huang, Y., Koo, B. B., Cedarbaum, J. M.
10.1101/2025.05.16.25327469 — Posted: 2025-06-23
Sub-second analysis of locomotor activity in Parkinsonian mice
Berezhnoi, D., Chehade, H. D., Simms, G., Chen, L., SIVANVAYAL NARASIMHAN, K. K., Dravid, S., Chu, H.-Y.
10.1101/2024.12.26.630411 — Posted: 2025-06-18
Generation of knock-in Cre and FlpO mouse lines for precise targeting of striatal projection neurons and dopaminergic neurons
Albarran, E., Fushiki, A., Nelson, A., Ng, D., Chaimowitz, C., Nikoobakht, L., Sippy, T., Peterka, D. S., Costa, R. M.
10.1101/2025.06.15.659794 — Posted: 2025-06-15
Internalized α-synuclein fibrils become truncated and resist degradation in neurons while glial cells rapidly degrade α-synuclein fibrils.
Karim, M. R., Tiegs, E., Gasparini, E., Schlichte, R., Vermilyea, S. C., Lee, M. K.
10.1101/2024.06.05.597615 — Posted: 2025-06-11

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