Channel:  The Howard Hughes Medical Institute (HHMI)

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Frequency dynamics predict viral fitness, antigenic relationships and epidemic growth
Figgins, M. D., Bedford, T.
10.1101/2024.12.02.24318334 — Posted: 2025-09-12
Atlas of innate immune responses to experimental cholera and IL22 treatment demonstrates protection by mucus-secreting cells
Suzuki, M., Hasegawa, Y., Zhang, H., Waldor, M. K.
10.1101/2025.09.12.675873 — Posted: 2025-09-12
HIF2-driven PTHrP Causes Cachexia and Hypercalcemia in Kidney Cancer: Treatment with HIF2 Inhibitors
Abu-Remaileh, M., Stransky, L. A., Bhalerao, N., Shirole, N. H., Jiang, Q., Saad, E., Machaalani, M., Vigeant, S. H., Woldemichael, H., Xu, C., Lu, J., Wei, H., Liu, Z., Sun, W., Enomoto, K., Choueiri, T. K., Pitarresi, J. R., Carr, S. A., Udeshi, N. D., Kaelin, W. G.
10.1101/2025.09.09.675147 — Posted: 2025-09-11
Mammalian ZAP and KHNYN can independently restrict CpG-enriched avian viruses
Becker, J. T., Mickelson, C. K., Pross, L. M., Sanders, A. E., Vogt, E. R., Shepherd, F. K., Wick, C., Barkhymer, A. J., Aron, S. L., Fay, E. J., Harris, R. S., Langlois, R. A.
10.1101/2024.12.23.629495 — Posted: 2025-09-10
A green lifetime biosensor for calcium that remains bright over its full dynamic range
van der Linden, F. H., Thornquist, S. C., ter Beek, R. M., Huijts, J. Y., Hink, M. A., Gadella, T. W. J., Maimon, G., Goedhart, J.
10.1101/2024.11.05.622032 — Posted: 2025-09-10
The gut microbiota directs vitamin A flux to regulate intestinal T cell development
Srinivasan, T., Dende, C., Ruhn, K. A., Moye, S. L., Johnson, A., Behrendt, C. L., Hassell, B., Vale, G., Kim, J., Lichterman, J. N., Liang, C., Arana, C., Raj, P., Zhan, X., McDonald, J. G., Koh, A. Y., Hooper, L. V.
10.1101/2025.09.08.674524 — Posted: 2025-09-10
Lysosomal RNA profiling reveals targeting of specific types of RNAs for degradation
Ray, G. J., Nardini, E., Keys, H. R., Lin, D. H., Sabatini, D. M., Bartel, D.
10.1101/2025.09.09.674968 — Posted: 2025-09-09
Enhancer activation from transposable elements in extrachromosomal DNA
Kraft, K., Murphy, S. E., Jones, M. G., Shi, Q., Bhargava-Shah, A., Luong, C., Hung, K. L., He, B. J., Li, R., Park, S. K., Montgomery, M., Weiser, N. E., Wang, Y., Luebeck, J., Bafna, V., Boeke, J. D., Mischel, P. S., Boettiger, A. N., Chang, H. Y.
10.1101/2024.09.04.611262 — Posted: 2025-09-08
Vnd and En are expressed in orthogonal stripes and act in a brief competence window to combinatorially specify NB7-1 and its early lineage
Anderson, N., Lai, S.-L., Doe, C. Q.
10.1101/2025.09.04.674256 — Posted: 2025-09-08
Tandem association of CLOCK:BMAL1 complexes on DNA enables recruitment of CBP/p300 through multivalent interactions
Sharma, D., Stoos, L., Torgrimson, M. R., Crosby, P., Franks, K. M., Parsley, N. C., Membreno, M., Kempf, G., Kater, L., Gustafson, C. L., Lee, H.-W., Rubin, S., Michael, A. K., Thoma, N. H., Partch, C. L.
10.1101/2025.09.04.674342 — Posted: 2025-09-07

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