Channel:  The Howard Hughes Medical Institute (HHMI)

1,971 Articles

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larch: mapping the parsimony-optimal landscape of trees for directed exploration
Barker, M., Milanov, O., Dumm, W., Rich, D., Turakhia, Y., Matsen, F. A.
10.1101/2025.10.29.685337 — Posted: 2025-10-31
HaloTrace: A spatiotemporally precise fluorescent readout of blood-brain barrier permeability in mice
Zucker, H. L., Konshina, E., Mitchell, P., Gu, C.
10.1101/2025.10.30.685531 — Posted: 2025-10-31
Trimodal brain-wide ultrasound imaging of brain-tumor interaction
Rabut, C., Shivaei, S., Heiles, B., Shapiro, M. G.
10.1101/2025.10.29.685462 — Posted: 2025-10-31
Microbial-inspired antidotes to repurpose toxic compounds as antibiotics
Samad, T. S., Ngambenjawong, C., Ko, H., Patel, S., DeAgazio, C., Fleming, H. E., Bhatia, S. N.
10.1101/2025.10.31.685078 — Posted: 2025-10-31
Sleep-dependent clearance of brain lipids by peripheral blood cells
Cho, B., Youngstrom, D. E., Killiany, S., Guevara, C., Randolph, C. E., Beveridge, C. H., Saklani, P., Chopra, G., Sehgal, A.
10.1101/2025.10.30.685668 — Posted: 2025-10-31
Sexual dimorphism in the complete connectome of the Drosophila male central nervous system
Berg, S., Beckett, I. R., Costa, M., Schlegel, P., Januszewski, M., Marin, E. C., Nern, A., Preibisch, S., Qiu, W., Takemura, S.-y., Fragniere, A. M. C., Champion, A. S., Adjavon, D.-Y., Cook, M., Gkantia, M., Hayworth, K. J., Huang, G. B., Kampf, F., Katz, W. T., Lu, Z., Ordish, C., Paterson, T., Stuerner, T., Trautman, E. T., Whittle, C. R., Burnett, L. E., Hoeller, J., Li, F., Loesche, F., Morris, B. J., Pietzsch, T., Pleijzier, M. W., Silva, V., Yin, Y., Ali, I., Bates, A. S., Beresford, R. J., Bogovic, J., Brooks, P., Cachero, S., Canino, B. S., Chaisrisawatsuk, B., Clements, J., Crowe, A
10.1101/2025.10.09.680999 — Posted: 2025-10-30
Mutational scanning of TnpB reveals latent activity for genome editing
Thornton, B. W.-L., Weissman, R. F., Rodriguez, J. E., Tran, R. V., Duong, B. T., Terrace, C. I., Nagalakshmi, U., Austin, G., Groover, E. D., Wang, F. Z., Park, J.-U., Georgieva, V., Tartaglia, J., Cho, M.-J., Dinesh-Kumar, S., Doudna, J. A., Savage, D.
10.1101/2025.02.11.637750 — Posted: 2025-10-30
Human Coronavirus HKU1 Neutralizing Monoclonal Antibodies Target Diverse Epitopes Within and Around the TMPRSS2 Receptor Binding Site
Wang, L., Joseph, J., Vasquez, S., Wrapp, D., Sheahan, T. P., Dzuvor, C. K. O., Rosen, O., Kirchdoerfer, R., Abiona, O. M., Hammond, C., Shi, W., Moak, S. P., Kong, W.-P., Zhang, Y., Eso, M. R., Brown, A. J., Ward, A., Baric, R. S., McLellan, J. S., Pierson, T. C., Mascola, J., Graham, B. S., Yassine, H., Barnes, C. O., Corbett-Helaire, K. S.
10.1101/2025.10.29.685445 — Posted: 2025-10-30
Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025
Kikawa, C., Huddleston, J., Loes, A. N., Turner, S. A., Lee, J., Barr, I. G., Cowling, B. J., Englund, J. A., Greninger, A. L., Harvey, R., Hasegawa, H., Ho, F., Lacombe, K., Leung, N. H., Lewis, N. S., Peck, H., Watanabe, S., Smith, D. J., Bedford, T., Bloom, J. D.
10.1101/2025.09.06.674661 — Posted: 2025-10-28
Faf1 accelerates p97-mediated protein unfolding by promoting ubiquitin engagement
Liao, Z., Arkinson, C., Martin, A.
10.1101/2025.10.27.684972 — Posted: 2025-10-28

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