Channel:  Babraham Institute

155 Articles

Inter-gastruloid heterogeneity revealed by single cell transcriptomics time course: implications for organoid based perturbation studies
Rosen, L. U., Stapel, L. C., Argelaguet, R., Barker, C. G., Yang, A., Reik, W., Marioni, J. C.
10.1101/2022.09.27.509783 — Posted: 2022-09-28
Determinants of receptor tyrosine phosphatase homophilic adhesion: structural comparison of PTPRK and PTPRM extracellular domains
Hay, I. M., Shamin, M., Caroe, E. R., Mohammed, A. S. A., Svergun, D. I., Jeffries, C. M., Graham, S. C., Sharpe, H. J., Deane, J. E.
10.1101/2022.06.23.497309 — Posted: 2022-08-31
NANOGP1, a tandem duplicate of NANOG, exhibits partial functional conservation in human naive pluripotent stem cells
Maskalenka, K., Alagoz, G., Krueger, F., Wright, J., Rostovskaya, M., Nakhuda, A., Bendall, A., Krueger, C., Walker, S., Scally, A., Rugg-Gunn, P.
10.1101/2022.08.18.504441 — Posted: 2022-08-19
Dietary change without caloric restriction maintains a youthful profile in ageing yeast
Horkai, D., Houseley, J.
10.1101/2022.07.19.500645 — Posted: 2022-07-20
Multi-omics analysis demonstrates a critical role for GLP methyltransferase in transcriptional repression during oogenesis
Demond, H., Hanna, C. W., Castillo-Fernandez, J., Santos, F., Papachristou, E. K., Segonds-Pichon, A., Kishore, K., D'Santos, C. S., Kelsey, G.
10.1101/2021.12.20.473460 — Posted: 2022-06-20
Native size exclusion chromatography-based mass spectrometry (SEC-MS) identifies novel components of the Heat Shock Protein 90-dependent proteome
Samant, R. S., Batista, S., Larance, M., Ozer, B., Milton, C. I., Bludau, I., Biggins, L., Andrews, S., Hervieu, A., Johnston, H. E., Al-Lazikhani, B., Lamond, A. I., Clarke, P. A., Workman, P.
10.1101/2022.05.23.492985 — Posted: 2022-05-23
Widespread allele-specific topological domains in the human genome are not confined to imprinted gene clusters.
Richer, S., Yuan, T., Schoenfelder, S., Hurst, L., Murrell, A., Pisignano, G.
10.1101/2022.04.26.489502 — Posted: 2022-05-16
Molecular mechanism of Afadin substrate recruitment to the receptor phosphatase PTPRK via its pseudophosphatase domain
Hay, I. M., Mulholland, K. E., Graham, S. C., Sharpe, H., Deane, J. E.
10.1101/2022.04.27.489754 — Posted: 2022-04-27
Chemical conversion of human conventional Pluripotent Stem Cells to Trophoblast Stem Cells
Zorzan, I., Betto, R. M., Rossignoli, G., Arboit, M., Drusin, A., Martini, P., Martello, G.
10.1101/2022.04.07.487453 — Posted: 2022-04-08
The AppNL-G-F mouse model of Alzheimer's disease is refractory to regulatory T cell treatment
Yshii, L., Mascali, L., Kouser, L., Lemaitre, P., Marino, M., Dooley, J., Burton, O., Haughton, J., Callaerts-Vegh, Z., de Strooper, B., Holt, M., Pasciuto, E., Liston, A.
10.1101/2022.03.11.483903 — Posted: 2022-03-14

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