Channel:  Babraham Institute

183 Articles

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CASM potentiates STING-driven NFκB signaling in immune cells
Benoit-Lizon, I., Pignol, C., Hooper, K., Truntzer, C., Radoua, A., Dal Zuffo, L., Lucas, J., Frenger, Q., Ponsardin, E., Cornebise, C., Cantaloube, I., Ratier, A., Aucagne, R., Hermetet, F., Shahoei, S. H., Nelson, E. R., Limagne, E., Poüs, C., Delomenie, C., Soulas-Sprauel, P., Gros, F., Vegran, F., Garrido, C., Ghiringhelli, F., Paul, C., Florey, O., Jacquin, E., Apetoh, L.
10.64898/2026.01.21.700774 — Posted: 2026-01-24
High-resolution promoter interaction analysis implicates genes involved in the activation of Type 3 Innate Lymphoid Cells in autoimmune disease risk
Malysheva, V., Ray-Jones, H., Lakes, N., Brown, R. A., Cazares, T. A., Clay, O., Ohayon, D., Artemov, P., Wayman, J. A., Yang, Z. F., Della Rosa, M., Petitjean, C., Booth, C., Ellaway, J. I. J., Barnes, J. R., Dangel, A. W., Saini, A., Orchard, W., Chen, X., Parameswaran, S., Burden, F., Frontini, M., Nagano, T., Fraser, P., Schoenfelder, S., Weirauch, M. T., Kottyan, L. C., Smith, D. F., Powell, N., Weimer, J. M., Oltz, E. M., Wallace, C., Miraldi, E. R., Waggoner, S., Spivakov, M.
10.1101/2022.10.19.512842 — Posted: 2026-01-11
Poising and connectivity of emergent human developmental enhancers in the transition from naive to primed pluripotency
Nocente, M. C., Della Rosa, M., Malcolm, A. A., Lister, G., Savin, I., Ray-Jones, H., Elderkin, S., Tian, R., Andrews, S., Bendall, A., Semprich, C. I., Kampmann, M., Malysheva, V., Rostovskaya, M., Rugg-Gunn, P., Spivakov, M.
10.1101/2025.10.02.679816 — Posted: 2025-11-25
NF-kappaB is a Central Regulator of Hypoxia-Induced Gene Expression
Shakir, D., Batie, M., Kwok, C.-S., Cook, S. J., Kenneth, N. S., Rocha, S.
10.1101/2025.01.08.631917 — Posted: 2025-11-13
Differential regulation of TCR-induced ZFP36 and ZFP36L1 expression by cyclosporin A in CD8+ T cells
Turner, M., Petkau, G., Mitchell, T., Zaucha, M., Jones Evans, M.
10.1101/2025.09.24.678222 — Posted: 2025-09-29
Protein degradation shapes developmental tempo in mouse and human neural progenitors
Nakanoh, S., Stamataki, D., Garcia-Perez, L., Azzi, C., Carr, H. L., Pokhilko, A., Doshi, L., Boezio, G. L. M., Melchionda, M., Howell, S., Yu, L., Skehel, M., Oxley, D., Andrews, S., Briscoe, J., Rayon, T.
10.1101/2024.08.01.604391 — Posted: 2025-09-27
A post-transcriptional regulatory checkpoint controls the response of tumor-infiltrating cytotoxic CD4+ T cells to immunotherapy
Vila de Mucha, M., Hlond, J., Costoya, C., Lau, C.-I., Sledzinska, A., Uddin, I., Navarrete, M., Shah, M., Mastrokalos, G., Karagianni, D., Bell, S. E., Nattress, C., Beattie, G., Tape, C. J., Turner, M., Quezada, S. A., Jenner, R. G.
10.1101/2025.09.09.675154 — Posted: 2025-09-12
Declining intracellular proteostasis capacity drives misfolded protein secretion in senescent human cells.
Watts, T., Johnston, H. E., Al-Mufti, Y., Odle, R. I., Hodgson, R., Okkenhaug, H., Carr, H., Cranwell, S., Wu, E., Walker, S., Andrews, S., Shelkovnikova, T., Samant, R. S.
10.1101/2025.09.07.674107 — Posted: 2025-09-08
Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis
Calado, D. P., Boulat, V., Alberts, E., Driscoll, P. C., Hung, M. S., Cunha, A., Quist, J., Liu, F., Brundin, C. A., Bhalla, A., Avalle, L., Rosekilly, J., Ryan, L., Gillett, C., Strom, M., Poli, V., MacRae, J. I., Grigoriadis, A.
10.1101/2025.08.30.673054 — Posted: 2025-09-04
Towards active vaccination against tumour endothelial marker Robo4
Escobar-Riquelme, F. N., Kara, M. A., Price, M., Hidalgo-Gajardo, A., Carr, H., Bending, D., Bicknell, R., Savelyeva, N., Zhang, Y., Toellner, K.-M.
10.1101/2025.08.28.672833 — Posted: 2025-09-02

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