Channel:  Babraham Institute

183 Articles

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Tissue-specific consequences of tag fusions on protein expression in transgenic mice
Taylor, G. C., Macdonald, L., Szulc, N. A., Gudauskaite, E., Moran, B. H., Brisbane, J. M., Donald, M., Taylor, E., Zheng, D., Gu, B., Mill, P., Yeyati, P. L., Pokrzywa, W., de Almeida, C. R., Wood, A. J.
10.1101/2025.06.18.660429 — Posted: 2025-06-18
Pervanadate-induced oxidation relieves autoinhibition of SRC protein tyrosine kinase
Mulholland, K. E., Bourguet, M., Cheng, N., Rahman, O., Ezerina, D., Daly, L. A., Lai, T., Casanova, S. A., Creixell, P., Eyers, C., Eyers, P., Messens, J., Byrne, D., Sharpe, H.
10.1101/2025.04.27.650842 — Posted: 2025-06-12
TrAEL-seq captures DNA replication dynamics in mammalian cells
Kara, N., Biggins, L., Grinkevich, V., Whale, A., Garran Garcia, P., Srinivasan, J., Rugg-Gunn, P., Andrews, S., Parry, A., Robinson, H. M. R., Houseley, J.
10.1101/2025.06.09.658559 — Posted: 2025-06-11
Non-canonical enhancers control gene expression and cell fate in human pluripotent stem cells
Cao, Y., Dovgusha, O., Ebrahimi, A., Bevan, S., Widmer, L., Torabi, F., Kurlovich, J., Rodriguez-Polo, I., Khan, S., Patel, M., Pradeepa, M. M., Guenesdogan, U., Schoenfelder, S.
10.1101/2025.06.01.657118 — Posted: 2025-06-01
VH-replacement shapes the antibody repertoire by targeting non-pairing heavy-chains
White, H. N., Chovanec, P., Biggins, L., French, E. C., Bullen, G., Andrews, S., Corcoran, A. E.
10.1101/2025.04.07.647564 — Posted: 2025-04-11
RAB5c controls the assembly of non-canonical autophagy machinery to promote phagosome maturation and microbicidal function of macrophages
Freitas-Filho, E. G., Zaidan, I., Fortes-Rocha, M., Alzamora-Terrel, D. L., Bifano, C., Castro, P. A., Piraine, R. E. A., Pinzan, C. F., Rezende, C. P., Boada-Romero, E., Almeida, F. B. R., Goldman, G., Florey, O., Cunha, L. D.
10.1101/2025.03.25.645097 — Posted: 2025-03-28
A transcriptional clock of the human pluripotency transition
Coussement, L., Ciarchi, M., Kolmogorova, A., De Meyer, T., Rulands, S., Reik, W., Rostovskaya, M.
10.1101/2025.03.13.643129 — Posted: 2025-03-13
An Nlrp5-null mutation leads to attenuated de novo methylation in oocytes, accompanied by a significant reduction in DNMT3L
Nic Aodha, L., Pokhilko, A., Rosen, L. U., Galatidou, S., Walewska, E., Belton, C., Galvao, A., Okkenhaug, H., Yu, L., Nakhuda, A., Mansfield, B., Khan, S., Oxley, D., Barragan, M., Kelsey, G.
10.1101/2025.02.20.639225 — Posted: 2025-02-23
The KRAB-Zinc Finger protein ZKSCAN3 represses enhancers via embedded retrotransposons
Moore, D., Wong, E., Arnal, C., Schoenfelder, S. W., Spivakov, M., Andrews, S., Christophorou, M. A.
10.1101/2025.01.30.635440 — Posted: 2025-01-31
RNA helicase DDX1 regulates germinal centre selection and affinity maturation by promoting tRNA ligase activity
Kimber, R., Ingelsfield, S., Screen, M., Salerno, F., Matheson, L. S., Okkenhaug, H., Whale, A., Assalaarachchi, J., Stammers, M., Akdeniz, D., Andrews, S., Ribeiro de Almeida, C.
10.1101/2025.01.10.632317 — Posted: 2025-01-14

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