Channel:  Babraham Institute

157 Articles

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Single-Cell Atlas of Common Variable Immunodeficiency reveals germinal center-associated epigenetic dysregulation in B cell responses
Rodriguez-Ubreva, J., Arutyunyan, A., Bonder, M. J., Del Pino-Molina, L., Clark, S., de la Calle-Fabregat, C., Garcia-Alonso, L., Handfield, L.-F., Ciudad, L., Andres-Leon, E., Krueger, F., Catala-Moll, F., Rodriguez-Cortez, V. C., Polanski, K., Mamanova, L., van Dongen, S., Kiselev, V. Y., Martinez-Saavedra, M. T., Heyn, H., Martin, J., Warnatz, K., Lopez-Granados, E., Rodriguez-Gallego, C., Stegle, O., Kelsey, G. D., Vento-Tormo, R., Ballestar, E.
10.1101/2021.12.20.473453 — Posted: 2021-12-21
GwEEP - A comprehensive approach for genome-wide efficiency profiling of DNA modifying enzymes
Kyriakopoulos, C., Nordström, K., Kramer, P. L., Gottfreund, J., Salhab, A., Arand, J., Müller, F., von Meyenn, F., Ficz, G., Reik, W., Wolf, V., Walter, J., Giehr, P.
10.1101/2020.08.06.236307 — Posted: 2021-11-25
The distinct effects of MEK and GSK3 inhibition upon the methylome and transcriptome of mouse embryonic stem cells
Spindel, J., Krueger, C., Krueger, F., Papachristou, E. K., Kishore, K., D'Santos, C. S., Reik, W.
10.1101/2021.11.18.469000 — Posted: 2021-11-18
Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation
Hanna, C. W., Huang, J., Belton, C., Reinhardt, S., Dahl, A., Andrews, S., Stewart, A. F., Kranz, A., Kelsey, G.
10.1101/2021.03.11.434836 — Posted: 2021-11-06
Modelling human zygotic genome activation in 8C-like cells in vitro
Taubenschmid-Stowers, J., Rostovskaya, M., Santos, F., Ljung, S., Argelaguet, R., Krueger, F., Nichols, J., Reik, W.
10.1101/2021.10.28.466259 — Posted: 2021-10-29
DNA replication during acute MEK inhibition drives acquisition of resistance through amplification of the BRAF oncogene
Channathodiyil, P., Segonds-Pichon, A., Smith, P. D., Cook, S. J., Houseley, J.
10.1101/2021.03.23.436572 — Posted: 2021-10-06
Solvent Precipitation SP3 (SP4) enhances recovery for proteomics sample preparation without magnetic beads
Johnston, H. E., Yadav, K., Kirkpatrick, J. M., Biggs, G. S., Oxley, D., Kramer, H. B., Samant, R. S.
10.1101/2021.09.24.461247 — Posted: 2021-09-24
Maternal Dppa2 and Dppa4 are dispensable for zygotic genome activation but important for offspring survival
Kubinyecz, O., Santos, F., Drage, D., Reik, W., Eckersley-Maslin, M. A.
10.1101/2021.09.13.460183 — Posted: 2021-09-14
An improved iCLIP protocol
Lee, F. C. Y., Chakrabarti, A. M., Hänel, H., Monzon-Casanova, E., Hallegger, M., Militti, C., Capraro, F., Sadee, C., Toolan-Kerr, P., Wilkins, O., Turner, M., König, J., Sibley, C., Ule, J.
10.1101/2021.08.27.457890 — Posted: 2021-08-27
Leptin Signalling in the Ovary of Diet-Induced Obese Mice Regulates Activation of Nod-Like Receptor Protein 3 Inflammasome
Adamowski, M., Wolodko, K., Oliveira, J., Castillo-Fernandez, J., Murta, D., Kelsey, G. D., Galvao, A.
10.1101/2021.08.16.456479 — Posted: 2021-08-17

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