Channel:  Aligning Science Across Parkinson's (ASAP)

543 Articles

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The mitochondrial unfolded protein response in human microglia disrupts neuronal-glial communication and promotes senescence
Perez Jimenez, M. J., Lam, A., Weissleder, C., Bertoli, F., Raji, H., Bosch, M., Nemazanyy, I., Kalb, S., Kehili, M., Hirschberg, I., Brunetti, D., Heckenbach, I., Scheibye-Knudsen, M., Deleidi, M.
10.1101/2024.09.03.610925 — Posted: 2026-05-27
Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum
Miller-Hansen, A. J., Zhu, M., Kovaleski, R. F., Demir, B., Lerner, T. N.
10.64898/2026.05.08.723861 — Posted: 2026-05-23
GPNMB and glycosphingolipid measurements in cerebrospinal fluid and plasma from Parkinson's disease patients
Fernandez-Suarez, M. E., Bush, R. J., Di Biase, E., Te Vruchte, D., Priestman, D., Cortina-Borja, M., Cooper, O., Hardy, J., Hallett, P., Isacson, O., Platt, F. M.
10.64898/2026.04.09.712000 — Posted: 2026-05-18
Elucidating the dysbiotic features of gut microbiome, interaction with the human genome, and utility as a biomarker for treatment of Parkinson disease.
Payami, H., Murchison, C. F., Antonello, G., Wallen, Z. D., Dean, M. N., Verster, A., Long, K. R., Waldron, L. D., Sampson, T. R., Standaert, D. G.
10.64898/2026.05.12.724602 — Posted: 2026-05-15
PINK1/Parkin-dependent mitophagy mediates astrocytic inflammatory responses to mitochondrial damage
Riley, J. F., Robbins, C. V., Holzbaur, E. L. F.
10.64898/2026.05.11.724378 — Posted: 2026-05-13
ATP13A4 gates extracellular polyamine levels to control excitatory synaptogenesis
van Veen, S., Meeus, E., Irala, D., Sakers, K., Liu, Z., Savage, J., Sejourne, G., Bindu, D. S., Ausloos, E., Grzesik, H. E., Dhondt, H., Schoonvliet, N., Van den Haute, C., Van Asselberghs, J., Montpeyo Garcia-Moreno, M., Wierda, K., Baekelandt, V., Platzer, K., Rostasy, K., Yap, K. L., Eggermont, J., Holt, M., Eroglu, C., Vangheluwe, P.
10.1101/2025.04.04.25325117 — Posted: 2026-05-12
Interaction of G2019S LRRK2 and metabolic syndrome in a two-hit mouse model of Parkinson's disease: LRRK2-driven systemic depletion of pyrimidine nucleosides
Ma, Y., Erb, M. L., Sipple, K. A., Offerman, A. V., Niu, J., Madaj, Z. B., Fu, Z., Lau, K. H., Moore, D. J.
10.64898/2025.12.31.697225 — Posted: 2026-05-12
A human lysosomal storage disorder toolkit for decoding proteome landscapes in cortical and dopaminergic-like induced neurons
Kraus, F., He, Y., Jiang, Y., Li, D., Ambaw, Y. A., Gasparoli, F. M., Paulo, J. A., Walther, T. C., Farese, R., Gygi, S. P., Wilfling, F., Harper, J. W.
10.1101/2025.10.08.681047 — Posted: 2026-05-10
An isogenic single-cell atlas of familial Parkinson's disease mutations reveals convergent changes in dopamine neurons
Syed, K. M., Dunnack, J., Paatz, S., Ajjarapu, K., Sahagun, A., Rio, D., Soldner, F., Bateup, H., Hockemeyer, D.
10.64898/2026.05.04.722458 — Posted: 2026-05-10
Cortical synaptic vulnerabilities revealed in a α-synuclein aggregation model of Parkinson's disease
Sah, S., Sauerbeck, A. D., Gupta, J., Perez-Acuna, D., Reiber, J. E., Russell, D., Goralski, T., Henderson, M., Volpicelli-Daley, L. A., Higley, M. J., Kummer, T. T., Biederer, T.
10.1101/2024.06.20.599774 — Posted: 2026-05-08

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