Channel: Aligning Science Across Parkinson's (ASAP)

477 Articles

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ATG2A engages Rab1a and ARFGAP1 positive membranes during autophagosome biogenesis

Fuller, D. M., Wu, Y., Schueder, F., Rasool, B., Nag, S., Korfhage, J. L., Garcia-Milian, R., Melnyk, K. D., Bewersdorf, J., De Camilli, P., Melia, T.

10.1101/2025.03.24.645038 — Posted: 2025-12-17

Clinical and imaging characteristics of Parkinson's disease with negative alpha-synuclein seed amplification assay

Brooker, S. M., Pasquini, J., Choi, S. H., Lafontant, D.-E., Fereshtehnejad, S.-M., Zeighami, Y., Grillo, P., Riboldi, G. M., Azizi, H., Moqadam, R., Kang, U. J., Nudelman, K. N. H., Siderowf, A., Tanner, C. M., Tropea, T. F., Foroud, T., Chahine, L. M., Mollenhauer, B., Merchant, K. M., Galasko, D., Coffey, C. S., Dobkin, R. D., Brown, E. G., Alcalay, R. N., Weintraub, D., Marek, K., Simuni, T., Latapi, P. G., Pavese, N., Poston, K. L.

10.1101/2025.10.01.25337085 — Posted: 2025-12-10

Striatal ensembles specify and control granular forelimb actions

Rodrigues-Vaz, I., Athalye, V. R., Peterka, D. S., Costa, R. M.

10.64898/2025.12.03.692128 — Posted: 2025-12-08

Elucidating an anterior cingulate circuit for self-initiated actions and rescue of Parkinsonian akinesia

Ulloa Severino, F., Lu, B., Kim, J., Friedman, A., Roshchina, M., Johnson, S., Bakhurin, K., Eroglu, C., Yin, H.

10.64898/2025.12.01.691607 — Posted: 2025-12-03

Tau, amyloid-beta and alpha-synuclein co-pathologies synergistically enhance neuroinflammation and neuropathology

Webster, J. M., Yang, Y.-T., Miller, A. T., Zane, A., Scholz, K., Stone, W. J., Corbin-Stein, N. J., Mudium, N., Won, W.-J., Stoll, A. C., Greathouse, K. M., Cooper, N. H., Long, L. F., Manuel, P. N., Herskowitz, J. H., Yacoubian, T. A., Tyrrell, D. J., Sandoval, I. M., Manfredsson, F. P., Kordower, J. H., Harms, A. S.

10.1101/2024.10.13.618101 — Posted: 2025-11-24

A Multimodal Atlas Reveals the Anatomical Distribution of Medium Spiny Neuron Subtypes and a Novel RGS6+ Population in the Primate Striatum

Abdelhady, G., Brull, O. R., He, J., Lin, M. K., Galvan, A., Pfenning, A. R., Bostan, A. C., Stauffer, W. R.

10.1101/2025.11.16.688724 — Posted: 2025-11-19

LRRK2 integrates Rab and GABARAP interactions to sense and respond to distinct lysosomal stresses

Clegg, D., Bentley-DeSousa, A., Roczniak-Ferguson, A., Ferguson, S. M.

10.1101/2025.11.19.689251 — Posted: 2025-11-19

Pathway and gates for ATG2A-mediated lipid transport in autophagy

Cabezudo, A. C., Holzer, E., Martens, S., Hummer, G.

10.1101/2025.11.16.688672 — Posted: 2025-11-16

Insights into the regulation of VPS13 family bridge-like lipid transfer proteins from the structure of VPS13C.

Li, D., Wang, X., Hu, B., Hao, H., Hamill, S., Li, Y., Chen, G., De Camilli, P., Reinisch, K.