Channel:  Francis Crick Institute

1,139 Articles

A single cell ATAC-seq atlas uncovers dynamic changes in chromatin accessibility during cell fate specification at the neural plate border
Harmrud, E., Leese, J., Thiery, A. P., Buzzi, A. L., Vigilante, A., Briscoe, J., Streit, A.
10.1101/2025.05.03.652017 — Posted: 2025-05-05
PEtab.jl: Advancing the Efficiency and Utility of Dynamic Modelling
Cvijovic, M., Persson, S., Frohlich, F., Grein, S., Lomna, T., Ognissanti, D., Hassselgren, V., Hasenauer, J.
10.1101/2025.04.30.651378 — Posted: 2025-05-04
Diverse Genomic Landscape of Swine Influenza A Virus in England (2014 - 2021)
Mollett, B. C., Byrne, A. M. P., Everett, H. E., Reid, S. M., Williamson, S., Anderson, T. K., James, J., Banyard, A. C., Brown, I. H., Lewis, N. S.
10.1101/2025.04.28.650978 — Posted: 2025-04-30
Distinct druggable biological processes in early-onset prostate cancer
Schmidt, S., Jarai, Z., Larkeryd, A., Ozer, B., Karlsson, Q., Campbell, J., Merson, S., Dennis, N., Hazell, S., Mitsopoulos, C., Cooper, C., ICGC-UK, T., Consortium, T., Russell, K., Workman, P., Eeles, R., Al-Lazikani, B.
10.1101/2025.04.25.650707 — Posted: 2025-04-29
VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment
Calderon, R. I., Sah, N., Huang, M., Kittle, R. H., Shaik, W., Chousal, J. N., Kallol, S., Bui, T., Morey, R., Mitre, A., Fogarty, N. M. E., Gerri, C., Zheng, C., DeHoff, P. M., Home, P., Niakan, K., Cook-Andersen, H., Fisch, K. M., Paul, S., Soncin, F.
10.1101/2025.04.25.650693 — Posted: 2025-04-29
Structure-Function Mapping of Olfactory Bulb Circuits with Synchrotron X-ray Nanotomography
Zhang, Y., Bosch, C., Ackels, T., Laugros, A., Bonnin, A., Livingstone, J., Waltenberg, C., Berning, M., Tootoonian, S., Kollo, M., Nathansen, A., Rzepka, N., Cloetens, P., Pacureanu, A., Schaefer, A.
10.1101/2025.04.24.650439 — Posted: 2025-04-27
Chromosome-Specific Aneuploidy Engineering via dCas9-Induced Centromeric Chromatin Relaxation
FENG, H., Deng, D., Dahiya, R., Wang, L., Zeng, J., Tan, B. J. Y., Byrne, F., Shepherd, S. T. C., Wang, J., Johnson, S. C., Harrod, A., Lane, K. A., Fendler, A., Cattin, A.-L., Tippu, Z., Nie, M., Zhao, Y., Wang, R., Ai, W., Bouricha, O., Barber, T., Dovga, Y., Xu, Y., Xu, Y., Devito, L. G., Healy, L., Sun, Z., Shen, W., Wang, H., Lim, E. S., OToole, S. M., Akker, S., Drake, W. M., Jin, H., Downs, J. A., McClelland, S. E., Diffley, J. F. C., Ly, P., Turajlic, S.
10.1101/2025.04.25.650684 — Posted: 2025-04-27
Volatile anaesthetics modulate voltage-gated sodium channel function at a site critical for gating
Hollingworth, D., Herold, K. F., Kelly, G., Mykhaylyk, V. B., Zhang, D., Wallace, B. A., Hemmings, H. C.
10.1101/2024.11.04.621342 — Posted: 2025-04-25
3D spatial transcriptomics reveals the molecular structure of input and output pathways in the mouse olfactory bulb
Klimpert, N., Kollo, M., Brann, D. H., Tan, C., Barry, D., Ma, Y., Schaefer, A. T., Fleischmann, A.
10.1101/2025.02.19.639192 — Posted: 2025-04-23
Chronobot: Deep learning guided time-resolved cryo-EM captures molecular choreography of RecA in homology search
Mäeots, M.-E., Tupin, S., Esfahani, N. M. M., Molina, J. B. R., Clapperton, J. A., Amin, A., Imbert, A., Enchev, R. I.
10.1101/2025.04.21.649820 — Posted: 2025-04-22

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