Channel:  Francis Crick Institute

1,153 Articles

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MRTF-dependent cytoskeletal dynamics drive efficient cell cycle progression
Nielsen, J. C., Benito-Jardon, M., Petrela, N. C., Diring, J., Bellamy, S., Treisman, R.
10.1101/2025.06.06.657372 — Posted: 2025-06-07
Multimodal profiling unveils a reversible basal-like breast cancer cell state resistant to AKT inhibition
Ratcliffe, C. D. H., Sparks, H., Boezio, G. L. M., Alexandrov, Y., Jenkins, R. P., Le Marois, A., Soro-Barrio, P., Lee, R., Strohbuecker, S., Joshi, S., Ellis, J. K., Fortier, A.-M., Gustafsson, N., Cunha, A. C., Park, M., MacRae, J. I., Serio, A., Briscoe, J., Riddell, A., Barry, S. T., Dunsby, C., Sahai, E.
10.1101/2025.06.06.658331 — Posted: 2025-06-07
Targeting Neutrophil Extracellular Traps to inhibit Colon Cancer Tumor Necrosis and Metastasis
Gazzara, E., Adrover, J. M., Lui, A., Han, S., Aminzada, Z., Bhandari, N., Sivetz, N., Shirue, V. S., Shergill, B. S., Curtis, M. B., George, S. C., Cicala, A., Rishi, A., Chung, C., Devoe, C., Huang, H., Weiss, M., Lou, E., Tuveson, D. A., Beyaz, S., Westcott, P. M. K., Egeblad, M., Gholami, S.
10.1101/2025.05.30.657122 — Posted: 2025-06-07
A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics
Autorino, C., Khoromskaia, D., Harari, L., Floris, E., Booth, H., Pallares-Cartes, C., Petrasiunaite, V., Dorrity, M., Corominas-Murtra, B., Hadjivasiliou, Z., Petridou, N.
10.1101/2025.06.06.658228 — Posted: 2025-06-06
C9orf72 polyGA knock-in mice exhibit mild motor and proteomic changes consistent with ALS/FTD
Milioto, C., Carcole, M., Zanovello, M., Ahmed, M., Nirujogi, R. S., Biggs, D., Katona, E., Glaria, I., Santos, A., Devoy, A., Fratta, P., Alessi, D. R., Davies, B., Greensmith, L., Fisher, E., Isaacs, A. M.
10.1101/2025.05.30.656994 — Posted: 2025-06-02
Beneficial and detrimental consequences of AHR activation in intestinal infection
Diaz, O. P., zhou, L., Barrington, C., Lindquist, D., Graelmann, F., Wincent, E., Stockinger, B.
10.1101/2025.05.28.656570 — Posted: 2025-06-01
Lysosomal stress induces amyloid-β aggregate release and reactive transformation in human astrocytes
Goldsworthy, S., Fertan, E., Dyal, P., Domoney, S., Livesey, F., Klenerman, D., Patani, R., Hung, C.
10.1101/2025.05.27.656416 — Posted: 2025-06-01
The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis
Roeselova, A., Shivakumaraswamy, S., Jurkeviciute, G., He, J.-Z., Auburger, J., Schmitt, J., Kramer, G., Bukau, B., Enchev, R. I., Balchin, D.
10.1101/2025.05.27.656346 — Posted: 2025-05-30
The penetrant chordoid glioma PRKCA mutation is an oncogenic gain-of-function kinase inactivation eliciting early onset chondrosarcoma in mice.
Calleja, v., Henry, J. C., Cobbaut, M., Sewell, J., Rizzoti, K., Houghton, F., Boeing, S., Anyanwu, N., Varsani-Brown, S., Snoeks, T., Suarez-Bonnet, A., Priestnall, S. L., McDonald, N. Q., Cameron, A. J., Parker, P. J.
10.1101/2025.05.28.656646 — Posted: 2025-05-29
Gene network architecture, mutation and selection collectively drive developmental pattern evolvability and predictability
Booth, H., Hadjivasiliou, Z.
10.1101/2024.12.23.630099 — Posted: 2025-05-29

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