Channel:  Francis Crick Institute

1,365 Articles

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iClima: a ratiometric genetically encoded sensor for optical imaging of fast GABAergic chloride currents in vitro and in vivo
Pasquini, G., Giubbolini, S., Nardi, G., Brondi, M., Beyene, E., Balsi, C., Egidi, A., Tsushima Semini, H., Landi, S., Stancampiano, M., Beale, A. D., Watson, E. M., Edgar, R. S., ONeill, J. S., Arosio, D., Santi, M., Fassio, A., Lodovichi, C., Ratto, G. M.
10.64898/2026.05.27.728254 — Posted: 2026-09-02
A COJEC-chemotherapy resistant model of Th-ALK(F1174L)/MYCN neuroblastoma offers insights into tumour immune evasion and development of the bone marrow metastatic niche
Tucker, E. R., Lampis, A., Househam, J., Roberts, D., Barker, K., Martins da Costa, B., Greenslade, K., Mayfield, S., Lorenzi, F., Thorley, E., Tandon, V., Han, N. S., Emanuelli, G., Bourdim, M., Martin, G., Willumsen, N., Pannone, M., Pryce, J., Angelini, P., Yuneva, M., Graham, T., George, S. L., Chesler, L.
10.64898/2026.09.01.743331 — Posted: 2026-09-02
Thymic keratin76 shapes skin-specific central tolerance
Gelmetti, M., Tomas, I. M., Ragazzini, R., Campinoti, S., Soon, M. S. F., Cautela, M., Vietri Rudan, M., Torre, M., Sumaria, N., Saldanha, I., Pereira, D., Yap, N., Efremova, M., Tuong, Z. K., Watt, F. M., Bonfanti, P., Pennington, D. J., Sequeira, I.
10.64898/2026.08.27.747460 — Posted: 2026-08-31
Single-cell mapping of the fallopian tube reveals a genomically unstable secretory cell state enriched in carriers of germline BRCA1/2 mutations
Eyal-Lubling, Y., Vias, M. D., Kania, K., Kaludova, D., Hall, J., Crawford, R., Nyagumbo, R., Ward, S., Khoronenkova, S., Aparicio, S., Swanton, C., Jimenez Linan, M., Brenton, J. D., Correia Martins, F.
10.64898/2026.08.26.746998 — Posted: 2026-08-27
Piezo1 balances focal and reticular adhesions to enable EGFR clathrin-mediated endocytosis
Bagudanch, O., Zoroa, O., Ayala, V., Midyan, R., Bagley, D. C., Moparthi, S. B., Hakanpää, L., Lenaerts, A.-S., Almeida-Souza, L., Munoz, F. J., Valverde, M. A., Vassilopoulos, S., Rosenblatt, J., Pardo-Pastor, C.
10.64898/2026.08.21.746250 — Posted: 2026-08-24
Chromosomal instability shapes spatial and temporal phenotypic diversity in a malignant peripheral nerve sheath tumour
Yan, H., Demeulemeester, J., Verfaillie, A., Cheng, Y., Pan, Y., Cotobal Martin, C., Ward, S., Stein, A., Lesluyes, T., Kaufmann, T., Schwarz, R. F., Voet, T., Swanton, C., Zaccaria, S., Flanagan, A. M., Tarabichi, M., Van Loo, P.
10.64898/2026.08.13.744699 — Posted: 2026-08-21
Symbolic regression enables coarse-grained model discovery of intracellular signalling dynamics
de Pomereu, T., Fröhlich, F.
10.64898/2026.08.20.745973 — Posted: 2026-08-21
MEN1 deficiency establishes a selenite-dependent binary switch in ferroptosis
Low, R. R. J., Parnandi, N., Idilli, A. I., Gjelaj, E., Subtil, F. T., Segura-Bayona, S., MacRae, J. I., Boulton, S. J.
10.64898/2026.07.16.738891 — Posted: 2026-08-12
Cooperative and antagonistic interactions between sub-clones favour the co-existence of multiple resistance mechanisms in melanoma
Schlegelmilch, K., Hollek, V., Hooper, S., Giangreco, G., Bailey, S., Macfarlane, S., Carminati, A., Bowes, A., Strohbuecker, S., Shum, B., Turajlic, S., Fu, X., Sahai, E.
10.1101/2025.10.23.684170 — Posted: 2026-08-10
Quantitative profiling of JMJD6-catalysed lysine hydroxylation reveals a graded, residue-dependent readout of oxygen availability
Kesavan, P., Stuermer, S. M., Räbel, K., Popp, O., Mertins, P., Cockman, M. E., Sugimoto, Y.
10.64898/2026.06.08.730680 — Posted: 2026-08-10

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