Channel:  Francis Crick Institute

1,302 Articles

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Histidine exchange sustains LAT1 activity and proliferation in glutamine-addicted breast cancers.
Gjelaj, E., Driscoll, P., Mahmood, A., Tarrago-Celada, J., Kossifos, M., Sesay, S., MacRae, J. I., Yuneva, M.
10.64898/2026.04.15.716193 — Posted: 2026-04-19
Phosphoregulated SMCR8-FIP200 interaction connects the ALS/FTD-linked C9orf72 complex to autophagy initiation and mitochondrial quality control
Wang, J., Davis, C., Kunzelmann, S., Maslen, S., Kelly, G., Skehel, M., Schreiber, A.
10.64898/2026.04.16.718395 — Posted: 2026-04-18
Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa
Du-Harpur, X., Ganier, C., Mazin, P., Cheshire, C., Gabriel, J. A., Rashidghamat, E., Luscombe, N. M., Lynch, M. D., Watt, F. M.
10.1101/2025.11.11.682326 — Posted: 2026-04-17
The Alzheimer's disease neurodegenerative cascade reconstructed in human L2/3 excitatory neurons
Zielonka, M., Mallach, A., De Strooper, B., Fiers, M.
10.64898/2026.04.14.718430 — Posted: 2026-04-15
Nonlinear mixed-effect models and tailored parametrization schemes enables integration of single cell and bulk data
Wang, D., Froehlich, F., Stapor, P., Schaelte, Y., Huth, M., Eils, R., Kallenberger, S., Hasenauer, J.
10.64898/2026.04.06.716803 — Posted: 2026-04-09
NucleoNet and DropNet: Generalist deep learning models for instance segmentation of nuclei and lipid droplets from electron microscopy images
Bhardwaj, A., Dell, C. W., Mikolaj, M. R., Spiers, H., Harned, A., Kuppusamy, B., Liu, P., Wei, D., Sterneck, E., Narayan, K.
10.64898/2026.04.02.713930 — Posted: 2026-04-05
BDNF Regulates Pituitary Stem Cell Engagement towards precursor state
Sochodolsky, K., Khetchoumian, K., Balsalobre, A., Feeley, R. M., Rice, M. E., Chakravarty, P., Lovell-Badge, R., Rizzoti, K., DROUIN, J.
10.64898/2026.04.02.716194 — Posted: 2026-04-04
Mycobacterium tuberculosis partitions the Krebs cycle under iron starvation
Serafini, A., Garza-Garcia, A., Sorze, D., de Carvalho, L. P. S., Manganelli, R.
10.1101/2025.05.12.653400 — Posted: 2026-04-04
Decomposing representational drift across wake and sleep
Harris, J. J., Schaefer, A. T., Kollo, M.
10.64898/2026.03.31.715372 — Posted: 2026-04-02
Plasmodium Protein Kinase 2 is required for ookinete to oocyst transition, and parasite transmission by the mosquito.
Pashley, S. L., Hair, M., Ukegbu, C. V., Zeeshan, M., Mishra, A., Brady, D., Vaughan, S., Pasquarello, C., Holder, A. A., Hainard, A., Guttery, D. S., Christophides, G. K., Vlachou, D., Sharma, P., Tewari, R.
10.64898/2026.03.27.714672 — Posted: 2026-04-02

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