Channel:  Francis Crick Institute

1,312 Articles

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Quantitative profiling of JMJD6-catalysed lysine hydroxylation reveals residue-dependent oxygen sensitivity
Kesavan, P., Stuermer, S. M., Räbel, K., Popp, O., Mertins, P., Cockman, M. E., Sugimoto, Y.
10.64898/2026.06.08.730680 — Posted: 2026-06-08
iSBEM: An Open-Source Workflow for Automated ROI Targeting in Volume Electron Microscopy
Ronchi, P., Ross, G., Burrell, A., de Folter, J., Klenz, Y., Darif, N., Young, F., Lawson, M., Albers, J., Pietz, T., Frischknecht, F., Duke, E., Roufosse, C., Collinson, L., Strange, A., Schwab, Y.
10.64898/2026.06.05.730298 — Posted: 2026-06-06
FIKK1, a member of the FIKK kinase family, phosphorylates VAR2CSA and regulates adhesion of Plasmodium falciparum-infected erythrocytes to the placental receptor CSA
Gamain, B., Semblat, J.-P., Eavis, H., Belda, H., Hamelin, R., Paquereau, C.-E., Doerig, C., Treeck, M., Dorin-Semblat, D.
10.64898/2026.03.23.713582 — Posted: 2026-06-05
Topology-aware reconstruction of cellular state landscapes from microscopy using self-supervised learning
Messori, E., Taha, D. M., Fournier, L., Foix Romero, A., Uhlmann, V., Frossard, P., Vincent-Cuaz, C., Patani, R., Luisier, R.
10.64898/2026.05.30.728966 — Posted: 2026-06-03
HKDC1 contributes to aberrant lysosome-mitochondria contact in Niemann-Pick disease type C
Pastore, R., Stanley, J., Kiraly, S., Dubois, C., Monfregola, J., de Luca, A., Guerra, G., Skehel, M., Ballabio, A., Platt, F. M., Eden, E. R.
10.64898/2026.06.01.729255 — Posted: 2026-06-02
CDKL5 phosphorylates neuronal ELAVL proteins to promote mRNA binding, protein synthesis and visual cortex development
Mihaylov, S. R., Lopes, A. T., Silvestre, M., Bianchini, G., Flynn, H. R., Huseynova, A., Strohbuecker, S., Griffith, L., Militti, C., Baltussen, L. L., Yuan, X., Morel, G., Claxton, S., Dempster, K., Lee, F. C. Y., Kanca, O., Köhn, M., Skehel, M., Ule, J., Iacaruso, F., Ultanir, S. K.
10.64898/2026.04.07.716766 — Posted: 2026-05-29
GROQ-seq Datasets Across Transcription Factors (LacI, RamR, VanR), T7 RNA Polymerase and TEV Protease
Spinner, A., Sreenivasan, S., McLellan, J. R., Ikonomova, S. P., Cortade, D. L., dOelsnitz, S., Sheldon, K., Vasilyeva, O. B., Alperovich, N. Y., Chadha, A., Nematollahi, L., Dhroso, A., Sisson, Z., Densmore, D., Hudson, C. M., DeBenedictis, E., Kelly, P. J., Reider Apel, A., Ross, D., Baranowski, C.
10.64898/2026.04.15.718744 — Posted: 2026-05-29
Lineage-specific retrotransposon co-option reveals a conserved ASH2L isoform as an epigenetic primer of developmental gene promoters
Elgood Hunt, E., Vivori, C., Mitter, R., Hannah Johnkingsly Jebaraj, J., Agnadottir, V., Delas, J., Serna Morales, E., Frith, T., Skehel, M., Elosegui-Artola, A., Briscoe, J., van Werven, F.
10.64898/2026.02.25.707914 — Posted: 2026-05-27
Endolysosomal damage promotes intraluminal protein condensate formation that limits cytosolic leakage
LI, X., Zhang, Y., ZHAO, K., Chen, G., Cui, D., Nikan, M., Young, S., Bennett, F., Seth, P. P., Ni, T., Gutierrez, M. G., Jiang, H.
10.64898/2026.05.25.726725 — Posted: 2026-05-25
Asymmetric Contrastive Objectives for Efficient Phenotypic Screening
Nightingale, L., Tuersley, J., Warchal, S., Cairoli, A., Howes, J., Shand, C., Powell, A., Green, D., Strange, A., Howell, M.
10.1101/2024.04.19.590313 — Posted: 2026-05-22

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