Channel:  Francis Crick Institute

1,252 Articles

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An injectable soft implant for long-acting, reversible, ultra-stable release of therapeutics
Stevens, M. M., Kütahya, C., Panariello, L., Najer, A., Rizou, T., Shamsabadi, A., Brachi, G., Peeler, D. J., Zharova, L., Fernandez Debets, T. F. F., Peschke, P., Constantinou, A. P., Xie, R., Cheng, Y., Burdis, R., Suarez-Bonnet, A., Cihova, M., Yeow, J., Schaufelberger, F., Malanchi, I.
10.64898/2026.02.25.707913 — Posted: 2026-02-26
Glucose concentration of neuronal media formulations influences PINK1-dependent mitophagy in human iNeurons
O'Callaghan, B., Melandri, D., Soltic, D., Cosker, K., Soutar, M. P. M., Evans, J. R., Lucas-Clarke, H., Robin, J., Gandhi, S., Birsa, N., Arber, C., Wray, S., Plun-Favreau, H.
10.1101/2025.04.01.646648 — Posted: 2026-02-26
Co-option of a mouse-specific retrotransposon rewires Ash2l isoform usage to prime developmental promoters
Elgood Hunt, E., Vivori, C., Mitter, R., Hannah Johnkingsly Jebaraj, J., Agnadottir, V., Delas, J., Serna Morales, E., Frith, T., Skehel, M., Elosegui-Artola, A., Briscoe, J., van Werven, F.
10.64898/2026.02.25.707914 — Posted: 2026-02-26
Myc inhibition triggers GM-CSF-driven regression of pancreatic tumours
Campos, T., Kortlever, R. M., Sodir, N. M., Buck, M. D., Stockis, J., Parker, J., Lam, C. M., Patino-Mercau, J. R., Perfetto, A., Edwards, A., Stefan, B., Halim, T. Y., Gerard, E. I.
10.64898/2026.02.24.707647 — Posted: 2026-02-25
PMGen: From Peptide-MHC Structure Prediction to Peptide Generation
Asgary, A. H., Aleyasin, A., Mehl, J. A., Fallah, S., Aintablian, H., Ludewig, B., Mishto, M., Liepe, J., Soeding, J.
10.1101/2025.11.14.688404 — Posted: 2026-02-25
The Structured RNA-binding Domains and Condensation Capacity of FUS Shape its RNA-binding Landscape and Function.
Jutzi, D., Alcalde, J., Hutten, S., Tiryaki, F., Davies, B., Plun-Favreau, H., Sibley, C., Dormann, D., Ruepp, M.-D.
10.64898/2026.01.12.699057 — Posted: 2026-02-22
Discrete genetic effects of VHL and PBRM1 inactivation co-operate to disrupt epithelial homeostasis and promote ccRCC
Kurlekar, S., Lima, J. D. C. C., Kupfer, N., Pugh, C. W., Mole, D. R., Adam, J., Ratcliffe, P. J.
10.64898/2026.02.18.706657 — Posted: 2026-02-20
Microglia Rank signaling regulates GnRH function and the Hypothalamic-Pituitary-Gonadal axis
Collado-Sole, A., Borjini, N., Zhai, J., Soria-Alcaide, G., Folgueira, C., Ruiz-Pino, F., Garcia Vilela, C., Lopez, V., Zouaghi, Y., Jacobs, A., Mora-Romero, B., Barranco, A., Yoldi, G., Rizzoti, K., Sabio, G., Perez-Chacon, G., G. Santamaria, P., Antonio Esteban, J., Pascual, A., Fernandez-Chacon, R., Tena-Sempere, M., Pitteloud, N., Gonzalez-Suarez, E.
10.64898/2026.02.18.706528 — Posted: 2026-02-18
Membrane lipid composition and endocytosis modulate Wingless release from secreting cells
Alvarez-Rodrigo, I., Alexandre, C., Lebarbachon, C., Borg, A., Finley, H., Arahouan, I., Zhao, Y., Di Pietro, F., Kjaer, S., Booth, P., Bauer, R., Jones, E. Y., Bellaiche, Y., Vincent, J.-P., Willnow, D.
10.64898/2026.02.12.705585 — Posted: 2026-02-18
Physiological febrile heat stress increases cytoadhesion through increased protein trafficking of Plasmodium falciparum surface proteins into the red blood cell
Jones, D., Belda, H., Broncel, M., Fuchs, G., Anaguano, D., Nofal, S. D., Treeck, M.
10.1101/2025.05.14.653932 — Posted: 2026-02-17

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