Channel:  Francis Crick Institute

1,290 Articles

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Mcm10 braces converging replicative helicases to pull apart origin DNA
Palm, G., Butryn, A., Canal, B., Pühringer, T., Gross, M. H., Diffley, J. F. X., Costa, A.
10.64898/2026.05.15.725099 — Posted: 2026-05-16
H3K27M-driven hypertranscription leads to a new targetable dependency in diffuse midline gliomas
PAL, S., Wang, H., Geisberg, J., Mirza, T., Kohli, K., Nazaretian, A., Knowles, T., Graser, C. J., Bootz, K., Wojcikowska, O., Bartynska, M., Boulton, S. J., Majithiya, J. B., Robinson, H., Smith, G., Stiles, C., Chowdhury, D., Agar, N. Y. R., Mueller, S., Michor, F., Haas-Kogan, D.
10.64898/2026.05.12.724628 — Posted: 2026-05-15
Decorrelation by gain control in the mouse olfactory bulb
Tootoonian, S., Yang, Y., Schaefer, A. T., Ackels, T.
10.64898/2026.05.07.722633 — Posted: 2026-05-11
Entropy Sorting Feature Selection: information-theoretic gene set identification improves single-cell RNA sequencing data interpretability
Radley, A., Boezio, G., Shand, C., Perez-Carrasco, R., Briscoe, J.
10.64898/2026.01.26.701684 — Posted: 2026-05-10
Selective Elimination of TP53 Mutant Cells by Transcript-Activated Chromatin Shredding
Zeng, J., Cheng, Z., Chen, H., Thompson, J., Crosby, K. T., Hang, H., Ngo, W., Xia, C., Rosas-Rivera, D., Kang, M. H., Mao, Y., Lee, G., Diffley, J. F. X., Song, Y., Qiu, L., Krah, N. M., Murthy, N., Jackson, R. N., Liu, Y., Ashworth, A., Doudna, J. A.
10.64898/2026.05.08.723607 — Posted: 2026-05-09
Scalable subclonal reconstruction of cancer cells in DNA sequencing data using a penalized likelihood model
Jiang, Y., Montierth, M. D., Ding, Y., Yu, K., Tran, Q., Wu, A., Li, R., Ji, S., Liu, X., Shin, S. J., Cao, S., Tang, Y., Lesluyes, T., Kimmel, M., Wang, J. R., Tarabichi, M., Zhu, H., Van Loo, P., Wang, W.
10.1101/2021.03.31.437383 — Posted: 2026-05-07
Dynamic modelling of human neural crest development using a bioengineered stem cell organoid system
Moreno-Gonzalez, C., Cameron, D., Marques Moreno, M., Desjardins, J., Minckley, T., Bailey, M., Hagemann, C., Bhatt, S., Tsakiridis, A., Serio, A., Liu, K. J.
10.64898/2026.05.04.721958 — Posted: 2026-05-06
Joint Variable Selection for Omic Biomarkers in Time-to-Event Data
Bajzik, J., Depope, A., Zolfimoselo, Y., Sharipov, A., Lesayova, A., Klein, H., Richmond, A., Vernardis, S., Grauslys, A., Andrejev, S., Zelezniak, A., Ralser, M., Marioni, R., Mondelli, M., Robinson, M. R.
10.64898/2026.04.30.721585 — Posted: 2026-05-04
HTLV-1 intasome recruits the PP2A-B56 holoenzyme and restricts its phosphatase activity
Minnell, J. J., Punch, E., Vanzo, T., Safari, R., Cronin, N. B., Cherepanov, P., Maertens, G. N.
10.64898/2026.05.01.722153 — Posted: 2026-05-04
Distinct functions of PBRM1 and BAP1 reconcile the course of kidney cancer evolution and disease progression
Deng, D., Feng, H., Fendler, A., Dovga, Y., Byrne, F., Spencer, C., Martin, A., Sanroman, A. F., Bouricha, O., Shepherd, S. T. C., Fu, H., Pallikonda, H., Lobon, I., Mulder, K., Guo, Q., Elphick, M., Wang, J., Franz, A., Ben-Akinduro, S., Cattin, A.-L., Tippu, Z., Ibarzo Yus, B., Barber, T., Hepworth, S., Symons, I., Edmonds, K., Carlyle, E., Modi, A., Korteweg, J., Schneider-Santos, A., Bickley, L., Larkin, J., Rudman, S., Bex, A., Turajlic, S.
10.64898/2026.04.30.721837 — Posted: 2026-05-03

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