Channel:  Francis Crick Institute

1,183 Articles

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Pregranulosa cells engage a distinct transcriptional programme prior to cell-cycle dependent primordial follicle activation
Taylor, G., Frost, E. R., Crow, B. N., Radley, A., Boeing, S., Galichet, C., Bucinskaite, B., Baker, M. A., Sutherland, J. M., Lovell-Badge, R.
10.1101/2022.10.24.513438 — Posted: 2025-09-05
Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis
Calado, D. P., Boulat, V., Alberts, E., Driscoll, P. C., Hung, M. S., Cunha, A., Quist, J., Liu, F., Brundin, C. A., Bhalla, A., Avalle, L., Rosekilly, J., Ryan, L., Gillett, C., Strom, M., Poli, V., MacRae, J. I., Grigoriadis, A.
10.1101/2025.08.30.673054 — Posted: 2025-09-04
Brain-derived neurotrophic factor amplifies neuron-intrinsic programs to enhance axonal regeneration in human motor neurons
Vargas, J. N. S., Brown, A.-L., Sun, K., Hagemann, C., Geary, B., Villarroel-Campos, D., Bryce-Smith, S., Zanovello, M., Lombardo, M., Majewski, S., Tosolini, A., Secrier, M., Keuss, M. J., Serio, A., Sleigh, J. N., Fratta, P., Schiavo, G.
10.1101/2023.11.06.565775 — Posted: 2025-09-04
The actomyosin cortex controls t-tubule remodeling in muscle
Pereira, A. R., Soares, A. d. R., Francescantonio, S. D., Liu, T., Carvalho, F. A., Ferreira, J. L., Leal, G., Faleiro, I., Kogata, N., Santos, N. C., Way, M., Moores, C., Gomes, E. R.
10.1101/2024.08.13.607563 — Posted: 2025-09-02
Balanced contractility and adhesion drive polarization in a minimal elastic actomyosin network
Messi, Z., Raynaud, F., Goehring, N. W., Verkhovsky, A. B.
10.1101/2025.08.26.672435 — Posted: 2025-08-29
Disease-attenuated pneumococcal biosynthesis gene mutants invade the mucosal epithelium and induce innate immunity
Weight, C. M., Pollara, G. M., Betts, M., Ragazzini, R., Connor, M., Ramos-Sevillano, E., Reine, J., Whelan, M., Guerra-Assuncao, J. A., Bonfanti, P., Jolly, C., Noursadeghi, M., Ferreira, D., Brown, J., Heyderman, R. S.
10.1101/2023.06.15.545009 — Posted: 2025-08-29
Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease
Evans, J. R., Grant-Peters, M., Beckwith, J. S., Toomey, C. E., Popovic, R., Breiter, J. C., Brenton, J. W., Fairbrother-Browne, A., Strohbuecker, S., Lachica, J., Rodriguez-Lopez, M., Brock, E. E., Fu, B., Nahidiazar, L., Lopez-Garcia, P., Ferguson, R., Saleeb, R. S., Lucas-Clarke, H., Penverne, A., D'Sa, K., Pang, C. W., Horrocks, M. H., Vendruscolo, M., Wood, N., Lee, S. F., Ryten, M., Gandhi, S.
10.1101/2025.08.25.671921 — Posted: 2025-08-28
Developmental Dynamics of Human Cardiogenesis: A multi-omic reference and its disruption in Trisomy 21
Cranley, J., Kanemaru, K., Bayraktar, S., Knight-Schrijver, V., Pett, J. P., Polanski, K., Dabrowska, M., Hulbert, R., Lana-Elola, E., Aoidi, R., Mulas, I., Richardson, L., Semprich, C., Kapuge, R., Perera, S., He, X., Ho, S. Y., Yayon, N., Tuck, L., Roberts, K., Palmer, J., Davaapil, H., Gambardella, L., Patel, M., Tyser, R., Tybulewicz, V., Sinha, S., Teichmann, S.
10.1101/2024.04.29.591736 — Posted: 2025-08-28
Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex
Nagar, A., Yanase, R., Zeeshan, M., Ferguson, D. J. P., Abel, S., Pashley, S. L., Mishra, A., Eze, A., Rea, E., Brady, D., Bottrill, A. R., Vaughan, S., Le Roch, K. G., Guttery, D. S., Holder, A. A., Tromer, E. C., Sharma, P., Tewari, R.
10.1101/2025.08.27.672654 — Posted: 2025-08-27
Developmental changes in the carotid body transcriptome accompanying the maturation of chemosensitivity
Hodson, E. J., Sugimoto, Y., Manamperige, R. S., Ford, S. G., Botting-Lawford, K. J., Niu, Y., Nathan, J. A., Giussani, D. A., Ratcliffe, P. J.
10.1101/2025.08.21.671502 — Posted: 2025-08-25

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