Channel:  Francis Crick Institute

1,330 Articles

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iClima: a ratiometric genetically encoded sensor for optical imaging of fast GABAergic chloride currents in vitro and in vivo
Pasquini, G., Giubbolini, S., Nardi, G., Brondi, M., Beyene, E., Balsi, C., Egidi, A., Tsushima Semini, H., Landi, S., Stancampiano, M., Beale, A. D., Watson, E. M., Edgar, R. S., ONeill, J. S., Arosio, D., Santi, M., Fassio, A., Lodovichi, C., Ratto, G. M.
10.64898/2026.05.27.728254 — Posted: 2026-09-02
The mTOR pathway drives daily physiology
Zeng, A., Mihut, A., Anandapadamanaban, M., Goity, A., de Barros Dantas, L. L., Peak Chew, S.-Y., Hayter, E. A., Andersson, L. C., Smith, T., Seinkmane, E., Stangherlin, A., James, N. R., Beresford, C., Farnsworth, J., Menzies, J., al-Rawi, A., Holt, L. J., Derivery, E., Edgar, R. S., Madsen, R. R., Bechtold, D. A., Larrondo, L. F., Dodd, A. N., Rihel, J., Ratto, G. M., Williams, J., Newham, P., Hilgendorf, C., Beale, A. D., Lodovichi, C., O'Neill, J. S.
10.64898/2026.08.28.747564 — Posted: 2026-08-31
Thymic keratin76 shapes skin-specific central tolerance
Gelmetti, M., Tomas, I. M., Ragazzini, R., Campinoti, S., Soon, M. S. F., Cautela, M., Vietri Rudan, M., Torre, M., Sumaria, N., Saldanha, I., Pereira, D., Yap, N., Efremova, M., Tuong, Z. K., Watt, F. M., Bonfanti, P., Pennington, D. J., Sequeira, I.
10.64898/2026.08.27.747460 — Posted: 2026-08-31
Single-cell mapping of the fallopian tube reveals a genomically unstable secretory cell state enriched in carriers of germline BRCA1/2 mutations
Eyal-Lubling, Y., Vias, M. D., Kania, K., Kaludova, D., Hall, J., Crawford, R., Nyagumbo, R., Ward, S., Khoronenkova, S., Aparicio, S., Swanton, C., Jimenez Linan, M., Brenton, J. D., Correia Martins, F.
10.64898/2026.08.26.746998 — Posted: 2026-08-27
Piezo1 balances focal and reticular adhesions to enable EGFR clathrin-mediated endocytosis
Bagudanch, O., Zoroa, O., Ayala, V., Midyan, R., Bagley, D. C., Moparthi, S. B., Hakanpää, L., Lenaerts, A.-S., Almeida-Souza, L., Munoz, F. J., Valverde, M. A., Vassilopoulos, S., Rosenblatt, J., Pardo-Pastor, C.
10.64898/2026.08.21.746250 — Posted: 2026-08-24
Symbolic regression enables coarse-grained model discovery of intracellular signalling dynamics
de Pomereu, T., Fröhlich, F.
10.64898/2026.08.20.745973 — Posted: 2026-08-21
Chromosomal instability shapes spatial and temporal phenotypic diversity in a malignant peripheral nerve sheath tumour
Yan, H., Demeulemeester, J., Verfaillie, A., Cheng, Y., Pan, Y., Cotobal Martin, C., Ward, S., Stein, A., Lesluyes, T., Kaufmann, T., Schwarz, R. F., Voet, T., Swanton, C., Zaccaria, S., Flanagan, A. M., Tarabichi, M., Van Loo, P.
10.64898/2026.08.13.744699 — Posted: 2026-08-21
MEN1 deficiency establishes a selenite-dependent binary switch in ferroptosis
Low, R. R. J., Parnandi, N., Idilli, A. I., Gjelaj, E., Subtil, F. T., Segura-Bayona, S., MacRae, J. I., Boulton, S. J.
10.64898/2026.07.16.738891 — Posted: 2026-08-12
Quantitative profiling of JMJD6-catalysed lysine hydroxylation reveals a graded, residue-dependent readout of oxygen availability
Kesavan, P., Stuermer, S. M., Räbel, K., Popp, O., Mertins, P., Cockman, M. E., Sugimoto, Y.
10.64898/2026.06.08.730680 — Posted: 2026-08-10
Cooperative and antagonistic interactions between sub-clones favour the co-existence of multiple resistance mechanisms in melanoma
Schlegelmilch, K., Hollek, V., Hooper, S., Giangreco, G., Bailey, S., Macfarlane, S., Carminati, A., Bowes, A., Strohbuecker, S., Shum, B., Turajlic, S., Fu, X., Sahai, E.
10.1101/2025.10.23.684170 — Posted: 2026-08-10

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