bioRxiv is receiving many new papers on coronavirus SARS-CoV-2.   A reminder: these are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information.

Channel : Francis Crick Institute

489 Articles

Early immune pressure imposed by tissue resident memory T cells sculpts tumour evolution in non-small cell lung cancer
Weeden, C. E., Gayevskiy, V., Trussart, M., Marceaux, C., Tubau Ribera, N., Batey, D., Teh, C. E., Mitchell, A. J., Antippa, P., Leong, T., Steinfort, D., Irving, L., Gordon, C. L., Swanton, C., Speed, T. P., Gray, D. H., Asselin-Labat, M.-L.
10.1101/2021.04.20.440373 — Posted: 2021-04-22
A systematic benchmark of Nanopore long read RNA sequencing for transcript level analysis in human cell lines
Chen, Y., Davidson, N., Wan, Y. K., Patel, H., Yao, F., Low, H. M., Hendra, C., Watten, L., Sim, A., Sawyer, C., Iakovleva, V., Lee, P. L., Xin, L., Ng, H. E. V., Loo, J. M., Ong, X., Ng, H. Q. A., Wang, J., Koh, W. Q. C., Poon, S. Y. P., Stanojevic, D., Tran, H.-D., Lim, K. H. E., Toh, S. Y., Ewels, P., Ng, H.-H., Iyer, N. G., Thiery, A., Chng, W. J., Chen, L., DasGupta, R., Sikic, M., Chan, Y.-S., Tan, B. O. P., Wan, Y., Tam, W. L., Yu, Q., Khor, C. C., Wuestefeld, T., Pratanwanich, P. N., Love, M. I., Goh, W. S. S., Ng, S., Oshlack, A., Goeke, J.
10.1101/2021.04.21.440736 — Posted: 2021-04-22
Sox8 is sufficient to reprogram ectoderm into ear vesicles and associated neurons
Buzzi, A. L., Chen, J., Thiery, A., Delile, J., Streit, A.
10.1101/2021.04.20.440617 — Posted: 2021-04-20
Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses
Banchenko, S., Krupp, F., Gotthold, C., Buerger, J., Graziadei, A., O' Reilly, F., Sinn, L., Ruda, O., Rappsilber, J., Spahn, C. M. T., Mielke, T., Taylor, I. A., Schwefel, D.
10.1101/2020.12.31.424931 — Posted: 2021-04-19
Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
Alvarez, E. G., Demeulemeester, J., Jolly, C., Garcia-Souto, D., Otero, P., Pequeno, A., Zamora, J., Tojo, M., Temes, J., Baez-Ortega, A., Rodriguez-Martin, B., Li, Y., Oitaben, A., Bruzos, A. L., Martinez-Fernandez, M., Haase, K., Santamarina, M., Zumalave, S., Abal, R., Rodriguez-Castro, J., Rodriguez-Casanova, A., Diaz-Lagares, A., Raine, K., Butler, A. P., Ono, A., Aikata, H., Chayama, K., Ueno, M., Hayami, S., Yamaue, H., Blanco, M. G., Forns, X., Rivas, C., Perez-del-Pulgar, S., Torres-Ruiz, R., Rodriguez Perales, S., Garaigorta, U., Nakagawa, H., Campbell, P. J., Van Loo, P., Tubio, J.
10.1101/2021.04.19.440412 — Posted: 2021-04-19
A gene regulatory network for neural induction
Trevers, K. E., Lu, H.-C., Yang, Y., Thiery, A., Strobl, A. C., Palinkasova, B., de Oliveira, N. M. M., de Almeida, I. M., Khan, M. A. F., Moncaut, N., Luscombe, N. M., Dale, L., Streit, A., Stern, C. D.
10.1101/2021.04.16.440164 — Posted: 2021-04-16
Developmental regulation of neuronal gene expression by Elongator complex protein 1 dosage.
Morini, E., Gao, D., Logan, E. M., Salani, M., Krauson, A. J., Chekuri, A., Chen, Y.-T., Ragavendran, A., Chakravarty, P., Erdin, S., Stortchevoi, A., Svejstrup, J. Q., Talkowski, M. E., Slaugenhaupt, S. A.
10.1101/2021.04.16.440179 — Posted: 2021-04-16
A suite of activity-based probes to dissect the KLK activome in drug-resistant prostate cancer
Lovell, S., Zhang, L., Kryza, T., Neodo, A., Bock, N., Williams, E. D., Engelsberger, E., Xu, C., Bakker, A. T., De Vita, E., Maneiro, M., Tanaka, R. J., Bevan, C. L., Clements, J. A., Tate, E. W.
10.1101/2021.04.15.439906 — Posted: 2021-04-15
Single-shot phase contrast microscopy using polarisation-resolved differential phase contrast
Kalita, R., Flanagan, W., Lightley, J., Kumar, S., Alexandrov, Y., Garcia, E., Hintze, M., Barkoulas, M., Dunsby, C., French, P. M. W.
10.1101/2021.04.14.437846 — Posted: 2021-04-14
Chromatin-contact atlas reveals disorder-mediated protein interactions
Rafiee, M.-r., Zagalak, J., Sidorov, S., Ule, J., Luscombe, N. M.
10.1101/2020.07.13.200212 — Posted: 2021-04-13

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