Channel:  Francis Crick Institute

1,203 Articles

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Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025
Kikawa, C., Huddleston, J., Loes, A. N., Turner, S. A., Lee, J., Barr, I. G., Cowling, B. J., Englund, J. A., Greninger, A. L., Harvey, R., Hasegawa, H., Ho, F., Lacombe, K., Leung, N. H., Lewis, N. S., Peck, H., Watanabe, S., Smith, D. J., Bedford, T., Bloom, J. D.
10.1101/2025.09.06.674661 — Posted: 2025-10-28
Transcript-Capture sequencing enriches mRNA of Mycobacterium tuberculosis from host samples
Lamont, E. I., Jones, R. M., Assadi, J., Morrison, R., Song, T., Yu, X., Wiener, D. M., Via, L. E., Winter, J., Ma, S. I., Wilkinson, R. J., Barry, C. E., Sherman, D. R.
10.1101/2025.10.28.685133 — Posted: 2025-10-28
Leveraging death of drug-sensitive cancer cells to promote immune-mediated bystander killing of subclones of drug-resistant tumor cells
Tomaschko, M., Ng, K., Moore, C., Pillsbury, C. E., Rana, S., Campbell, J., Mukherjee, S., Mikolajczak, A., Anastasiou, P., de Castro, A., Alonso de la Vega, A., de Carne Trecesson, S., Goehring, N., Molina-Arcas, M., Downward, J.
10.1101/2025.10.27.684825 — Posted: 2025-10-28
SERINC5 Is the Primary Target of Retroviral Antagonists Among Human SERINC Paralogs and Requires a Tri-Cysteine Motif for Its Counteraction by HIV-1 Nef
Bertelli, C., Rosa, A., Vanzo, T., Chande, A., Serwa, R., Tate, E. W., Cherepanov, P. P., Pizzato, M.
10.1101/2025.10.27.684794 — Posted: 2025-10-27
Cooperative and antagonistic interactions between sub-clones favour the co-existence of multiple resistance mechanisms in melanoma
Schlegelmilch, K., Hollek, V., Hooper, S., Giangreco, G., Bailey, S., Macfarlane, S., Carminati, A., Bowes, A., Strohbuecker, S., Fu, X., Sahai, E.
10.1101/2025.10.23.684170 — Posted: 2025-10-24
Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding
Boezio, G. L. M., Depotter, J. R. L., Frith, T. J. R., Radley, A., Strohbuecker, S., Cunha, A. C., Howell, M., Briscoe, J.
10.1101/2025.10.24.684328 — Posted: 2025-10-24
Multicellular Calcium Waves in Cancer-Associated Fibroblasts Regulate Neuronal Mimicry and Anisotropy Leading to Immune Exclusion
Giangreco, G., Ramsden, Z., Rullan, A., Hooper, S., Novo, D., Castro, J. L., Chakravarty, P., Milan, M., Mohammadi, H., Llop, S., Juarez, M., Schneider-Luftman, D., Oliva, M., Alemany, L., Angelova, M., Olow, A., Yu, X., Hobson, P., Harrington, K. J., Sahai, E.
10.1101/2025.10.23.684281 — Posted: 2025-10-24
Inhibition of neutrophil degranulation by Nexinhib20 delays the development of radiation-induced pulmonary fibrosis
Ruhland, S., Nikolatou, K., Bridgeman, V. L., Rizou, T., Sahai, E., Bordoloi, J., Nolan, E., Elosegui-Artola, A., Malanchi, I.
10.1101/2025.10.22.684057 — Posted: 2025-10-23
Autoantibody origins in lupus and in relapse post CAR-T therapy
Grenov, A., Yoon, J., Snell, D. M., Mikolajczak, A., Wang, H., Gurel, E., Rodriguez-Ronchel, A., Yegen, G., Lee, L., Artim Esen, B., Rahman, A., Maciocia, P., Vinuesa, C.
10.1101/2025.10.20.683393 — Posted: 2025-10-20
Genome-wide Chromosome-specific Aneuploidy Engineering and Phenotypic Characterization with CRISPR-Taiji
Feng, H., Deng, D., Dahiya, R., Wang, L., Zeng, J., Tan, B. J. Y., Byrne, F., Shepherd, S. T. C., Wang, J., Johnson, S. C., Harrod, A., Lane, K. A., Fendler, A., Cattin, A.-L., Tippu, Z., Nie, M., Zhao, Y., Wang, R., Ai, W., Bouricha, O., Barber, T., Dovga, Y., Xu, Y., Shen, W., Sun, Z., Wang, H., Zhu, J., Xu, Y., Devito, L. G., Healy, L., Lim, E. S., OToole, S. M., Akker, S., Drake, W. M., Jin, H., Downs, J. A., McClelland, S. E., Diffley, J. F. C., Ly, P., Turajlic, S.
10.1101/2025.04.25.650684 — Posted: 2025-10-18

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