Channel:  Francis Crick Institute

1,213 Articles

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Oncogenic RAS activity is linked to immune priming and adenosine-driven immune evasion in lung adenocarcinoma
de Carne Trecesson, S., East, P., Pillsbury, C., Silva dos Santos, M., Cha, H., Colliver, E., Gilmore, T., Rana, S., Moore, C., Lighterness, S., Caswell, D. R., Boumelha, J., Tomaschko, M., Baer, R., Eyles, J., Teixeira, B., Saeed, M., Litchfield, K., Molina-Arcas, M., Lee, S.-H., MacRae, J., Hobson, P., Swanton, C., Downward, J.
10.1101/2025.11.25.690426 — Posted: 2025-11-26
A divergent Plasmodium NEK4 acts as a key regulator driving the early events of meiosis
Yanase, R., Hair, M., Zeeshan, M., Ferguson, D. J. P., Brady, D., Pasquarello, C., Bottrill, A., Bhanvadia, S., Neal, A., Tromer, E. C., Le Roch, K. G., Hainard, A., Holder, A. A., Vaughan, S., Guttery, D. S., Tewari, R.
10.1101/2025.11.21.689802 — Posted: 2025-11-23
Rv3400 is a phosphoglucomutase required for trehalose metabolism in Mycobacterium tuberculosis
Liu, Y., Ruecker, N., Faulkner, V., Rachineni, K., Al-Saffar, N., VillacampaTeixeira, P., Dias da Costa, T., Johnson, E., Robertson, B. D., Ehrt, S., Larrouy-Maumus, G.
10.1101/2025.11.20.689507 — Posted: 2025-11-20
XIST Drives X-Chromosome Inactivation and Safeguards Female Extraembryonic Cells in Humans
Panda, A., Carrillo, L., Balaton, B. P., Brouillet, J., Nshemereirwe, S., Bonroy, J., Alfeghaly, C., Facchinello, R., Khodeer, S., Boers, R., Castel, G., London, C., Cazottes, E., Moscatelli, M., Tchinda, R. S., Pham, T. X. A., To, S. K., Allsop, R. N., Wang, Y., Staneva, D., Rugg-Gunn, P., Niakan, K., Gribnau, J., Ouimette, J.-F., Rougeulle, C., Pasque, V.
10.1101/2025.11.19.689206 — Posted: 2025-11-19
PETRA: Prime editing of transcribed regulatory elements to assay expression
Reyes, M. A., Herger, M., Cubitt, L., Findlay, G. M.
10.1101/2025.11.18.689114 — Posted: 2025-11-18
Human airway epithelia clear rhinovirus-infected cells using two waves of cell extrusion
Fore, F., Bagley, D. C., Martinez-Nunez, R. T., Aniscenko, J., Johnston, S., Rosenblatt, J.
10.1101/2025.11.18.689008 — Posted: 2025-11-18
Multimodal profiling unveils a reversible breast basal-like cell state in AKT-inhibitor resistant tumours
Ratcliffe, C. D. H., Sparks, H., Boezio, G. L. M., Alexandrov, Y., Jenkins, R. P., Le Marois, A., Soro-Barrio, P., Moughari, F. A., Hulme, H., Lee, R. J., Strohbuecker, S., Joshi, S., Ellis, J. K., Fabrini, G., Flint, L., Fortier, A.-M., Gustafsson, N., Cunha, A. C., Tully, L., Park, M., Frohlich, F., MacRae, J. I., Natrajan, R., Serio, A., Briscoe, J., Riddell, A., Barry, S. T., Dunsby, C., Sahai, E.
10.1101/2025.06.06.658331 — Posted: 2025-11-17
PMGen: From Peptide-MHC Prediction to Neoantigen Generation
Asgary, A. H., Aleyasin, A., Mehl, J. A., Ludewig, B., Mishto, M., Liepe, J., Soeding, J.
10.1101/2025.11.14.688404 — Posted: 2025-11-14
Siglec-engaging immunosuppressive sialoglycans are upregulated in prostate cancer and are targetable to suppress bone metastasis
Peng, Z., Hodgson, K., Fisher, M., Mei, S., Orozco-Moreno, M., Cao, L., Kemp, M., Gatlin, W., Donald, L., Zeng, F., Lawson, M. A., Ungar, D., Sykes, D. B., Elliott, D. J., Peng, L., Schumann, B., Wang, N., Munkley, J.
10.1101/2025.11.12.687981 — Posted: 2025-11-13
Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa
Du-Harpur, X., Ganier, C., Mazin, P., Cheshire, C., Rashidghamat, E., Luscombe, N. M., Lynch, M. D., Watt, F. M.
10.1101/2025.11.11.682326 — Posted: 2025-11-12

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