Channel:  RNA Therapeutics Institute at UMass Chan Med School

137 Articles

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Dual targeting of hepatocyte DGAT2 and stellate cell FASN alleviates nonalcoholic steatohepatitis in mice.
Yenilmez, B., Harney, S. M., DiMarzio, C., Kelly, M., Min, K., Echeverria, D., Bramato, B. M., Jackson, S. O., Reddig, K., Kim, J. K., Khvorova, A., Czech, M. P.
10.1101/2023.07.05.547848 — Posted: 2023-07-05
Genome-wide kinetic profiling of pre-mRNA 3' end cleavage
Torres-Ulloa, L., Calvo-Roitberg, E., Pai, A. A.
10.1101/2023.06.21.545926 — Posted: 2023-06-22
Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope
Bamidele, N., Zhang, H., Dong, X., Gaston, N., Cheng, H., Kelly, K., Watts, J. K., Xie, J., Gao, G., Sontheimer, E. J.
10.1101/2023.04.14.536905 — Posted: 2023-04-18
Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo
Zhang, H., Kelly, K., Lee, J., Echeverria, D., Cooper, D., Panwala, R., Chen, Z., Gaston, N., Newby, G. A., Xie, J., Liu, D. R., Gao, G., Wolfe, S. A., Khvorova, A., Watts, J. K., Sontheimer, E. J.
10.1101/2023.03.20.533459 — Posted: 2023-03-23
Epigenetic regulation of innate immune genes and enhanced interleukin-10 expression underlie chronic subclinical Plasmodium chabaudi infection
de Souza Silva, L., Nguyen, Y. A. H., Monks, B. G., Forconi, C. S., Crabtree, J. N., Rodriguez, T., Tamburro, N. D. P., Sontheimer, E. J., Horvath, G. L., Abdullah, Z., Latz, E., Caffrey, D. R., Kurt-Jones, E., Gazzinelli, R. T., Fitzgerald, K. A., Golenbock, D. T.
10.1101/2023.02.23.529826 — Posted: 2023-02-24
Broadly effective ACE2 decoy proteins protect mice from lethal SARS-CoV-2 infection
Lu, M., Yao, W., Li, Y., Ma, D., Zhang, Z., Wang, H., Tang, X., Wang, Y., Li, C., Cheng, D., Lin, H., Yin, Y., Zhao, J., Zhong, G.
10.1101/2023.02.22.529625 — Posted: 2023-02-23
Quantification of gallium cryo-FIB milling damage in biological lamella
Lucas, B. A., Grigorieff, N.
10.1101/2023.02.01.526705 — Posted: 2023-02-03
From primordial clocks to circadian oscillators
Pitsawong, W., Padua, R. A., Grant, T., Hoemberger, M., Otten, R., Bradshaw, N., Grigorieff, N., Kern, D.
10.1101/2022.11.28.518275 — Posted: 2022-11-29
Formamide significantly enhances the efficiency of chemical adenylation of RNA sequencing ligation adaptors
Hildebrand, S., Hedger, A. K., Watts, J., Khvorova, A.
10.1101/2022.11.16.516815 — Posted: 2022-11-16
Career Self-Efficacy Disparities in Underrepresented Biomedical Scientist Trainees
Chatterjee, D., Jacob, G. A., Sturzenegger Varvayanis, S., Wefes, I., Chalkley, R., Nogueira, A. T., Fuhrmann, C., Varadarajan, J., Hubbard, N. M., Gaines, C. H., Layton, R. L., Chaudhary, S.
10.1101/2022.10.21.512368 — Posted: 2022-10-21

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