Channel:  RNA Therapeutics Institute at UMass Chan Med School

137 Articles

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Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP
Carbone, C. E., Loveland, A. B., Gamper, H., Hou, Y.-M., Demo, G., Korostelev, A. A.
10.1101/2021.05.31.446434 — Posted: 2021-05-31
Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model
Hammer, M., Huisman, M., Rigano, A., Boehm, U., Chambers, J. J., Gaudreault, N., North, A. J., Pimentel, J. A., Sudar, D., Bajcsy, P., Brown, C. M., Corbett, A. D., Faklaris, O., Lacoste, J., Laude, A., Nelson, G., Nitschke, R., Farzam, F., Smith, C., Grunwald, D., Strambio-De-Castillia, C.
10.1101/2021.04.25.441198 — Posted: 2021-05-31
Widespread occurrence of hybrid internal-terminal exons in human transcriptomes
Fiszbein, A., McGurk, M., Calvo-Roitberg, E., Kim, G., Burge, C., Pai, A. A.
10.1101/2021.05.27.446076 — Posted: 2021-05-29
Programming large target genomic deletion and concurrent insertion via a prime editing-based method: PEDAR
Jiang, T., Zhang, X.-O., Weng, Z., Xue, W.
10.1101/2021.05.12.443800 — Posted: 2021-05-13
Cryo-TEM simulations of amorphous radiation-sensitive samples using multislice wave propagation.
Himes, B. A., Grigorieff, N.
10.1101/2021.02.19.431636 — Posted: 2021-05-08
Locating Macromolecular Assemblies in Cells by 2D Template Matching with cisTEM
Lucas, B. A., Himes, B. A., Xue, L., Grant, T., Mahamid, J., Grigorieff, N.
10.1101/2021.04.20.440648 — Posted: 2021-04-21
The testis-specific transcription factor TCFL5 responds to A MYBto elaborate the male meiotic program in placental mammals
Ozata, D. M., Yu, T., Cecchini, K., Mou, H., Arif, A., Colpan, C., Adriano Biasini, A., Gainetdinov, I., de Rooij, D. G., Weng, Z., Zamore, P.
10.1101/2021.04.04.438419 — Posted: 2021-04-05
Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice
Liu, P., Liang, S., Zheng, C., Mintzer, E., Zhao, Y. G., Ponnienselvan, K., Mir, A., Sontheimer, E. J., Gao, G., Flotte, T. R., Wolfe, S., Xue, W.
10.1101/2020.12.15.422970 — Posted: 2021-03-17
5' Modifications Improve Potency and Efficacy of DNA Donors for Precision Genome Editing
Ghanta, K. S., Chen, Z., Mir, A., Dokshin, G. A., Krishnamurthy, P. M., Yoon, Y., Gallant, J., Xu, P., Zhang, X.-O., Ozturk, A., Shin, M., Idrizi, F., Liu, P., Gneid, H., Lawson, N. D., Rivera-Perez, J. A., Sontheimer, E. J., Watts, J. K., Mello, C. C.
10.1101/354480 — Posted: 2021-03-04
Quantifying and Mitigating Motor Phenotypes Induced by Antisense Oligonucleotides in the Central Nervous System
Moazami, M. P., Rembetsy-Brown, J. M., Wang, F., Krishnamurthy, P. M., Weiss, A., Marosfoi, M., King, R. M., Motwani, M., Gray-Edwards, H., Fitzgerald, K. A., Brown, R. H., Watts, J. K.
10.1101/2021.02.14.431096 — Posted: 2021-02-15

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