Channel:  RNA Therapeutics Institute at UMass Chan Med School

137 Articles

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Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation
Demo, G., Loveland, A. B., Svidritskiy, E., Gamper, H. B., Hou, Y.-M., Korostelev, A. A.
10.1101/2020.12.29.424751 — Posted: 2020-12-29
Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved AS-NMD pathways
Kovalak, C. A., Donovan, S., Bicknell, A. A., Metkar, M., Moore, M. J.
10.1101/847004 — Posted: 2020-12-28
Translation-dependent and independent mRNA decay occur through mutually exclusive pathways that are defined by ribosome density during T Cell activation.
Mercier, B. C., Labaronne, E., Cluet, D., Bicknell, A., Corbin, A., Guiguettaz, L., Aube, F., Modolo, L., Auboeuf, D., Moore, M. J., Ricci, E. P.
10.1101/2020.10.16.341222 — Posted: 2020-10-17
CRISPR-enhanced human adipocyte 'browning' as cell therapy for metabolic disease
Tsagkaraki, E., Nicoloro, S., De Souza, T., Solivan-Rivera, J., Desai, A., Shen, Y., Kelly, M., Guilherme, A., Henriques, F., Ibraheim, R., Amrani, N., Luk, K., Maitland, S., Friedline, R. H., Tauer, L., Hu, X., Kim, J. K., Wolfe, S. A., Sontheimer, E. J., Corvera, S., Czech, M. P.
10.1101/2020.10.13.337923 — Posted: 2020-10-13
Precision Cas9 Genome Editing in vivo with All-in-one, Self-targeting AAV Vectors
Ibraheim, R., Tai, P. W. L., Mir, A., Javeed, N., Wang, J., Rodriguez, T. C., Nelson, S., Khokhar, E., Mintzer, E., Maitland, S., Cao, Y., Tsagkaraki, E., Wolfe, S. A., Wang, D., Pai, A. A., Xue, W., Gao, G., Sontheimer, E. J.
10.1101/2020.10.09.333997 — Posted: 2020-10-09
HDAC1 SUMOylation promotes Argonaute directed transcriptional silencing in C. elegans
Kim, H., Ding, Y.-H., Zhang, G., Yan, Y.-H., Conte, D., Dong, M.-Q., Mello, C.
10.1101/2020.08.17.254466 — Posted: 2020-09-19
PIE-1 promotes SUMOylation and activation of HDAC1 during the C. elegans oogenesis
Kim, H., Ding, Y.-H., Lu, S., Zuo, M.-Q., Conte, D., Dong, M.-Q., Mello, C.
10.1101/2020.08.17.253955 — Posted: 2020-09-19
Terminal Modification, Sequence, and Length Determine Small RNA Stability in Animals
Gainetdinov, I., Colpan, C., Cecchini, K., Albosta, P., Jouravleva, K., Vega-Badillo, J., Lee, Y., Ozata, D., Zamore, P. D.
10.1101/2020.09.08.287979 — Posted: 2020-09-08
CASCADES, a novel SOX2 super-enhancer associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma multiforme
Shahzad, U., Li, C., Johnston, M., Wang, J. J., Sabha, N., Varn, F. S., Riemenschneider, A., Krumholtz, S., Meda, P., Smith, C., Karamchandani, J., Watts, J. K., Verhaak, R. G. W., Gallo, M., Rutka, J. T., Das, S.
10.1101/2020.09.05.284349 — Posted: 2020-09-06
Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM
Loveland, A. B., Svidritskiy, E., Susorov, D., Lee, S., Park, A., Demo, G., Gao, F.-B., Korostelev, A. A.
10.1101/2020.08.30.274597 — Posted: 2020-08-31

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