Channel:  RNA Therapeutics Institute at UMass Chan Med School

137 Articles

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Piwi and piRNAs repress transcription of aberrant rRNA genes containing retrotransposon fragments
Fefelova, E. A., Shatskikh, A. S., Mikhaleva, E. A., Abramov, Y. A., Lavrov, S. A., Pirogov, S. A., Poltorachenko, V. A., Ilin, A. A., Zamore, P. D., Klenov, M. S.
10.1101/2025.04.30.651568 — Posted: 2025-04-30
In-Situ High-Resolution Cryo-EM Reconstructions from CEMOVIS
Elferich, J., Kaminek, M., Kong, L., Odriozola, A., Kukulski, W., Zuber, B., Grigorieff, N.
10.1101/2025.03.29.646093 — Posted: 2025-03-31
Single-dose administration of therapeutic divalent siRNA targeting MECP2 prevents lethality for one year in an MECP2 duplication mouse model
Hariharan, V. N., Summers, A., Caiazzi, J., Hildebrand, S., OReilly, D., Tang, Q., Kennedy, Z., Echeverria, D., McHugh, N., Cooper, D., Sousa, J., Ferguson, C., Clipperton-Allen, A., Bogdanik, L., Coenraads, M., Khvorova, A.
10.1101/2025.03.26.645328 — Posted: 2025-03-29
Defining the roles of the Integrator, NEXT, and nuclear exosome complexes in Drosophila oogenesis
Lee, Y., Biasini, A., Tipping, C., Hong, S. H., Zamore, P.
10.1101/2025.03.05.641556 — Posted: 2025-03-11
Pol II degradation activates cell death independently from the loss of transcription
Harper, N. W., Birdsall, G. A., Honeywell, M. E., Pai, A. A., Lee, M. J.
10.1101/2024.12.09.627542 — Posted: 2025-01-14
Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance
Zhang, B., Orning, P., Lehman, J. W., Dinis, A., Torres-Ulloa, L., Elling, R., Kelliher, M. A., Bertin, J., Proulx, M. K., Ryan, L., Kandasamy, R. K., Espevik, T., Pai, A. A., Fitzgerald, K. A., Lien, E.
10.1101/2024.11.27.625707 — Posted: 2024-11-29
Dynamic cytoplasmic fluidity during morphogenesis in a human fungal pathogen
Serrano, A., Puerner, C., Plumb, E., Chevalier, L., Elferich, J., Sinn, L. R., Grigorieff, N., Ralser, M., Delarue, M., Bassilana, M., Arkowitz, R. A.
10.1101/2024.11.16.623909 — Posted: 2024-11-17
Rational Design of Enhanced Nme2Cas9 and Nme2SmuCas9 Nucleases and Base Editors
Bamidele, N., Ansodaria, A., Chen, Z., Cheng, H., Panwala, R., Jazbec, E., Sontheimer, E. J.
10.1101/2024.10.30.620986 — Posted: 2024-11-07
Mouse Pachytene piRNAs Cleave Hundreds of Transcripts,But Alter the Steady-State Abundance of Only a Minority of Targets
Cecchini, K., Ajaykumar, N., Bagci, A., Zamore, P., Gainetdinov, I.
10.1101/2024.11.02.621675 — Posted: 2024-11-03
Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryo-electron tomography
Huang, Q. Y., Kim, R., Song, K., Grigorieff, N., Munro, J., Schiffer, C. A., Somasundaran, M.
10.1101/2024.10.15.618557 — Posted: 2024-10-18

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