Channel:  The Howard Hughes Medical Institute (HHMI)

2,708 Articles

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mRNAbow: A versatile gene expression system for multiplexed fluorescent imaging using optimized in vitro transcribed mRNA
Choi, H., Halanych, C., Kasberg, W., Testa, M. D., Rubin-Elgressy, S., Nguyen, P., Walpita, D., Tsang, A., Cortes, D., Song, E. Y., Wu, H., Weissman, I. L., Espinosa-Medina, I., Satou, C., Song, J. L., Matus, D. Q., Lippincott-Schwartz, J.
10.64898/2026.01.02.697412 — Posted: 2026-01-02
ABCC1 protects skin dendritic cells from FITC-induced toxicity by efflux and extracellular glutathione buffering
Knopper, K., Rao, A., An, J., Cyster, J. G.
10.64898/2026.01.02.697391 — Posted: 2026-01-02
Memory from variability: Heritable short-term cellular memory emerges from stochastic biochemical reaction networks
Aronson, M. S., Zhou, B. Y., Fitzgerald, J. E., Sgro, A. E.
10.64898/2025.12.31.694479 — Posted: 2026-01-01
Innate immune sensing via the cGAS-STING pathway restricts extrachromosomal DNA-driven tumorigenesis
Li, T., Yang, Q.-L., Qiao, K., Zhang, A., Sun, C., Huang, H., Mischel, P. S., Wu, S., Chen, Z. J.
10.64898/2025.12.31.697191 — Posted: 2026-01-01
Functional and antigenic constraints on the Nipah virus fusion protein
Larsen, B. B., Harari, S., Gen, R., Stewart, C., Veesler, D., Bloom, J. D.
10.1101/2025.10.15.682664 — Posted: 2026-01-01
Mitochondrial depolarization stabilizes the vitamin B12 chaperone MMADHC in the cytosol to increase MTR activity
Rath, S. P., Li, Z., Guha, A., Dong, F., Banerjee, R., Mootha, V. K.
10.64898/2025.12.31.697091 — Posted: 2025-12-31
A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform
Jain, S., Williamson, K. E., Ying, A. W., Turner, A. M., Jiang, R. J., Raval, S., So, K., Allison, M. P., Sankar, A., Same Guerra, D. D., Lin, Y., Jiang, Z., Mashtalir, N., Rohrs, H. W., Lichti, C. F., Muir, T. W., Papanastasiou, M., Paulo, J. A., Gygi, S. P., Gross, M. L., Kadoch, C.
10.1101/2025.08.01.667725 — Posted: 2025-12-31
Discovery of the metalloenzyme IsmB revises a pathway for coprostanol formation by the human gut microbiome
Tinoco, A., Li, C., Khurana, J., Banuelos Jara, B., Plichta, D. R., Kenny, D., Xavier, R. J., Balskus, E. P.
10.64898/2025.12.29.696961 — Posted: 2025-12-30
Template-based RNA structure prediction advanced through a blind code competition
Lee, Y., He, S., Oda, T., Rao, G. J., Kim, Y., Kim, R., Kim, H., Heng, C. K., Kowerko, D., Li, H., Nguyen, H., Sampathkumar, A., Enrique Gomez, R., Chen, M., Yoshizawa, A., Kuraishi, S., Ogawa, K., Zou, S., Paullier, A., Zhao, B., Chen, H.-L., Hsu, T.-A., Hirano, T., Gezelle, J. G., Haack, D., Hong, Y., Jadhav, S., Koirala, D., Kretsch, R. C., Lewicka, A., Li, S., Marcia, M., Piccirilli, J., Rudolfs, B., Srivastava, Y., Steckelberg, A.-L., Su, Z., Toor, N., Wang, L., Yang, Z., Zhang, K., Zou, J., Baker, D., Chen, S.-J., Chiu, W., Demkin, M., Favor, A., Hummer, A. M., Joshi, C. K., Kryshtafovyc
10.64898/2025.12.30.696949 — Posted: 2025-12-30
PtdIns(3,5)P2 Is an Endogenous Ligand of STING in Innate Immune Signaling
Tan, J. X., Lv, B., Li, J., Li, T., Du, F., Chen, X., Zhang, X., Bai, X.-c., Chen, Z. J.
10.64898/2025.12.29.696917 — Posted: 2025-12-29

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