Channel:  The Howard Hughes Medical Institute (HHMI)

2,398 Articles

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VTA dopamine neuron activity produces spatially organized value representations
Pan-Vazquez, A., Zimmerman, C. A., McMannon, B., Fabre, J. M. J., Louka, M., Jia, T., Sagiv, Y., West, S. J., Faulkner, M., Brain Laboratory, I., Dayan, P., Witten, I. B.
10.1101/2025.11.04.685995 — Posted: 2025-11-06
The proteomic landscape and temporal dynamics of mammalian gastruloid development
Garge, R. K., Lynch, V., Fields, R., Casadei, S., Best, S., Stone, J., Snyder, M., Kubo, C., Wakimoto, A., Liu, Z., McGann, C. D., Shendure, J., Starita, L. M., Hamazaki, N., Schweppe, D. K.
10.1101/2024.09.05.609098 — Posted: 2025-11-05
Large-scale discovery of neural enhancers for cis-regulation therapies
McDiarmid, T. A., Page, N. F., Chardon, F. M., Daza, R. M., Chen, G. T., Kosicki, M., James, L. M., Nourie, H. C., Laboy-Cintron, D., Lee, A. S., Vij, P., Calderon, D., Lalanne, J.-B., Martin, B. K., Fink, K., Talkowski, M. E., Muotri, A. R., Philpot, B. D., Pennacchio, L. A., Geschwind, D. H., Sanders, S. J., Ahituv, N., Shendure, J.
10.1101/2025.11.04.686611 — Posted: 2025-11-05
Identification of distinct cDC2 subpopulations that direct microbiota-specific T cell differentiation
Carroll, S. L., Ly, A., Liu, A. K., Canesso, M. C. C., Victora, G. D., Mucida, D., Barton, G. M.
10.1101/2025.11.04.686414 — Posted: 2025-11-05
Chromosome-scale genome assembly and annotation of the two-spotted cricket Gryllus bimaculatus (Orthoptera: Gryllidae)
Kataoka, K., Sanno, R., Gaczorek, T., Bhattarai, U. R., Ito, Y., Inoue, S., Yura, K., Asahi, T., Ylla, G., Mito, T., Extavour, C. G.
10.1101/2025.10.31.685973 — Posted: 2025-11-03
A membrane-bound nuclease directly cleaves phage DNA during genome injection
Saxton, D. S., Deweirdt, P. C., Doering, C. R., Roney, I. J., Laub, M. T.
10.1101/2025.11.03.685801 — Posted: 2025-11-03
Blind Prediction of Complex Water and Ion Ensembles Around RNA in CASP16
Kretsch, R. C., Posani, E., Baulin, E. F., Bujnicki, J. M., Bussi, G., Cheatham, T. E., Chen, S.-J., Elofsson, A., Farsani, M. A., Fisher, O. N., Gromiha, M. M., Gupta, A., Hamada, M., Harini, K., Hu, G., Huang, D., Iwakiri, J., Jain, A., Kagaya, Y., Kihara, D., Kmiecik, S., Krishnan, S. R., Kurisaki, I., Languin-Cattoen, O., Li, J., Li, S., Malekzadeh, K., Nakamura, T., Ni, W., Nithin, C., Palo, M. Z., Park, J. H., Pilla, S. P., Poblete, S., Pucci, F., Punuru, P., Saha, A., Sato, K., Srivastava, A., Terashi, G., Tugolukova, E., Verburgt, J., Wuyun, Q., Zerze, G. H., Zhang, K., Zhang, S., Zhen
10.1101/2025.11.03.685595 — Posted: 2025-11-03
B lymphocytes that enter the germinal center late preferentially differentiate into memory cells that recognize subdominant epitopes
Zhou, P., Hartweger, H., MacLean, A. J., Ramos, V., Yao, K.-h., Hernandez, B., Wang, Z., Gazumyan, A., Nussenzweig, M. C.
10.1101/2025.10.30.685663 — Posted: 2025-11-01
Adapting CRISPR-associated transposons for rapid and high-throughput reverse genetics
Basta, D. W., Zingl, F. G., Yang, Y., Nguyen, K. T., Liu, Y.-Y., Waldor, M. K.
10.1101/2025.10.31.685825 — Posted: 2025-11-01
De novo design of metal-oxide templating proteins
Saragovi, A., Pyles, H., Huddy, T. F., Li, X., Borst, A. J., Hanikel, N., Courbet, A., Kwon, P., Davila-Hernandez, F. A., Kibler, R. D., Vafeados, D. K., Allen, A., Carr, K. D., Bera, A., Kang, A., Brackenbrough, E., Schmid, S., Bae, Y., Stewart, L., Zhang, S., De Yoreo, J., Baker, D.
10.1101/2024.06.24.600095 — Posted: 2025-11-01

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