Channel:  The Howard Hughes Medical Institute (HHMI)

2,124 Articles

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Replaying germinal center evolution on a quantified affinity landscape
DeWitt, W. S. S., Vora, A. A., Araki, T., Galloway, J. G., Alkutkar, T., Bortolatto, J., Castro, T. B., Dumm, W., Jennings-Schaffer, C., Jia, T., Mesin, L., Ozorowski, G., Pae, J., Ralph, D. K., Bloom, J. D., Nourmohammad, A., Song, Y. S., Ward, A., Starr, T. N., Matsen, F. A., Victora, G. D.
10.1101/2025.06.02.656870 — Posted: 2025-06-05
A covalent recognition strategy enables conspecific mate identification
Jang, S. S., Mandala, S., Jiang, H., Zhang, X., Cole, P. A., del Marmol, J. I.
10.1101/2025.05.30.657074 — Posted: 2025-06-03
Transforming descending input into motor output: An analysis of the Drosophila Male Adult Nerve Cord connectome
Cheong, H. S. J., Eichler, K., Stuerner, T., Asinof, S. K., Champion, A. S., Marin, E. C., Oram, T. B., Sumathipala, M., Venkatasubramanian, L., Namiki, S., Siwanowicz, I., Costa, M., Berg, S., Janelia FlyEM Project Team, , Jefferis, G. S. X. E., Card, G. M.
10.1101/2023.06.07.543976 — Posted: 2025-06-03
Polyserine-tau interactions modulate tau fibrilization
Pratt, J., McCann, K., Kuo, J., Parker, R.
10.1101/2025.06.03.657713 — Posted: 2025-06-03
Structural basis of liver de-targeting and neuronal tropism of CNS-targeted AAV capsids
Brittain, T. J., Jang, S., Coughlin, G. M., Barcelona, B. H., Giriat, I., Ristic, F., Appling, N., Chossis, C. P., Shay, T. F., Gradinaru, V.
10.1101/2025.06.02.655683 — Posted: 2025-06-03
Persistent dopamine-dependent remodeling of the neural transcriptome in response to pregnancy and postpartum
Chan, J. C., Di Salvo, G., Cunningham, A. M., Dutta, S., Brindley, E. A., Weekley, B. H., Wan, E., Zhang, C., Mechawar, N., Turecki, G., Maze, I.
10.1101/2025.02.20.639313 — Posted: 2025-06-02
The SHR/Akr Y chromosome reveals repeated turnover of the rat pseudoautosomal region
Bellott, D. W., Skaletsky, H., Hughes, J., Brown, L. G., Pyntikova, T., Cho, T.-J., Koutseva, N., Zaghlul, S., Kizghin, D., Mendoza, M., Raudsepp, T., Dugan, S., Khan, Z., Wang, Q., Watt, J., Worley, K. C., Scherer, S., Muzny, D. M., Gibbs, R. A., Page, D. C.
10.1101/2025.05.28.656580 — Posted: 2025-06-01
Cell-type-specific patterns and consequences of somatic mutation in development and aging brain
Kriz, A. J., Mao, S., Shao, D. D., Snellings, D. A., Andersen, R., Dong, G., Ma, C. C., Cline, H. E., Huang, A. Y., Lee, E. A., Walsh, C. A.
10.1101/2025.05.30.656844 — Posted: 2025-06-01
A primate model organism for cardiac arrhythmias identifies a magnesium transporter in pacemaker function
Chang, S., Karanewsky, C. J., Pendleton, J. L., Ren, L., Anzeraey, A., Froelicher, V., Liang, D., Razafindrakoto, A., Ravelonjanahary, H. N., Albertelli, M. A., Quertermous, T., Wright, P. C., Perret, M., Terrien, J., Aujard, F., Wu, J. C., Krasnow, M. A.
10.1101/2025.05.28.655959 — Posted: 2025-06-01
Bacterial and host enzymes modulate the inflammatory response produced by the peptidoglycan of the Lyme disease agent
McCausland, J. W., Kloos, Z. A., Irnov, I., Sonnert, N. D., Zhou, J., Putnick, R., Mueller, E. A., Steere, A. C., Palm, N. W., Grimes, C. L., Jacobs-Wagner, C.
10.1101/2025.01.08.631998 — Posted: 2025-05-31

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