Channel:  The Howard Hughes Medical Institute (HHMI)

2,326 Articles

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An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics
Picard, C. L., Ichino, L., Buckley, T. J., Boone, B. A., Abuhanna, K. D., Zhang, Y., Behrendt, N. J., May Lei Soe, S., Luo, C., Jacobsen, S. E.
10.1101/2025.10.13.682236 — Posted: 2025-10-15
Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas
St. Laurent, J. D., Xu, G. D., Ying, A. W., Gokbayrak, B., Patil, A., Paulo, J. A., Cervantes, K. S., Chen, S., Feng, W. W., Sankar, A., Same Guerra, D. D., Qi, J., Neel, D. S., Hornick, J. L., Kolin, D. L., Gygi, S., Huntsman, D. G., Wang, Y., Kadoch, C.
10.1101/2025.10.13.681937 — Posted: 2025-10-15
Mapping cellular targets of covalent cancer drugs in the entire mammalian body
Pang, Z., Leung, V. H., Wang, C. C., Attarpour, A., Rinaldi, A., Shen, H., Moya-Garzon, M. D., Sigua, L. H., Rammel, C., Selke, A., Glynn, C., Yender, M., Xu, S., Moslehi, J. J., Wu, P., Long, J. Z., Goubran, M., Cravatt, B. F., Ye, L.
10.1101/2025.03.28.645991 — Posted: 2025-10-14
The complete genome of a songbird
Formenti, G., Jain, N., Medico, J. A., Sollitto, M., Antipov, D., Balacco, J., Barcellos, S., Biegler, M. T., Borges, I., Chang, J. K., Chen, Y., Cheng, H., Conceicao, H. B., Davenport, M., De Oliveira, L. C., Duarte, E., Durham, G. P., Fenn, J., Forde, N., Kim, J., Komissarov, A., Koo, B., Koren, S., Galante, P. A. F., Gerhardt, K., Giani, A. M., Giunta, S., Larkin, D., Lee, C., Li, H., Makova, K., Masterson, P., Murphy, T., McCaffrey, K., Mercuri, R. L. V., Na, Y., O Connell, M. J., Ou, S., Phillippy, A. M., Popova, M., Rhie, A., Ruiz-Ruano, F. J., Secomandi, S., Smeds, L., Suh, A., Tilley
10.1101/2025.10.14.682431 — Posted: 2025-10-14
Ecological cues orchestrate concerted courtship in a Drosophila host specialist
Brand, P., Keller, K., Coleman, R. T., Eghbali, N. B., Zylka, S., Prieto-Godino, L. L., Ruta, V.
10.1101/2025.10.13.681913 — Posted: 2025-10-14
Primary metabolism determines the outcome of salicylic acid-mediated immune induction
Zhang, Q., Xie, Y., Karapetyan, S., Wang, J., Mwimba, M., Yoo, H., Dong, X.
10.1101/2025.10.13.682132 — Posted: 2025-10-14
A reference brain for the clonal raider ant
Frank, D. D., Lopes, L. E., Mohanta, R., Seckler, I., Lacroix, I., Kronauer, D. J. C.
10.1101/2025.10.13.679875 — Posted: 2025-10-14
The mycomembrane proteins PorH and ProtX are inserted at polar growth zones and linked to the cell wall
Hart, E. M., de Bruin, D. A., Marando, V. M., Alemany, M. A., Snow, E. D., Schultz, B. J., Kuru, E., Walker, S., Vettiger, A., Bernhardt, T. G.
10.1101/2025.10.14.682376 — Posted: 2025-10-14
High-Throughput De Novo Protein Design Yields Novel Immunomodulatory Agonists
Abedi, M., Exposit, M., Coventry, B., Mathew, D., Jain, S., Krishnakumar, A., Goreshnik, I., Gray-Gaillard, S., Lunn-Halbert, M., Yu, T.-Y., Glögl, M., Mitchell, U., Keshri, R., Chun, J. H., Ruohola-Baker, H., Wherry, E. J., Baker, D.
10.1101/2025.10.12.681920 — Posted: 2025-10-13
Direct cell reprogramming by a designed agonist inducing HER2-FGFR proximity
Keshri, R., Exposit, M., Abedi, M., R Hicks, D., Foreman, Z., Phal, A., Lim, Y. C., Barrett, P., Sniezek, C., Lin, J., Schlichthaerle, T., J Robinson, A., Detraux, D., Ching, T. C., Wu, K., Coventry, B., Chang, L., S.T. Smith, A., L Mack, D., K Schweppe, D., Martin, B. E., Hristova, K., Mathieu, J., Baker, D., Ruohola-Baker, H.
10.1101/2025.10.12.681903 — Posted: 2025-10-13

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