Channel:  Aligning Science Across Parkinson's (ASAP)

392 Articles

Visualizing chaperone-mediated multistep assembly of the human 20S proteasome
Adolf, F., Du, J., Goodall, E. A., Walsh, R. M., rawson, S., von Gronaua, S., Harper, J. W., Hanna, J., Schulman, B. A.
10.1101/2024.01.27.577538 — Posted: 2024-01-28
Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
Erb, M. L., Sipple, K., Levine, N., Chen, X., Moore, D. J.
10.1101/2024.01.25.577280 — Posted: 2024-01-26
3D Bioprinting of Human Neural Tissues with Functional Connectivity
Yan, Y., Li, X., Gao, Y., Mathivanan, S., Kong, L., Tao, Y., Dong, Y., Li, X., Bhattacharyya, A., Zhao, X., Zhang, S.-C.
10.1101/2024.01.18.576289 — Posted: 2024-01-23
A pathogenic variant in RAB32 causes autosomal dominant Parkinsons disease and activates LRRK2 kinase
Gustavsson, E. K., Follett, J., Trinh, J., Barodia, S. K., Real, R., Liu, Z., Grant-Peters, M., Fox, J. D., Appel-Cresswell, S., Stoessl, J. A., Rajput, A., Rajput, A. H., Auer, R., Tilney, R., Sturm, M., Haack, T. B., Lesage, S., Tesson, C., Brice, A., Vilarino-Gueell, C., Ryten, M., Goldberg, M. S., West, A. B., Hu, M. T., Morris, H. R., Sharma, M., Gan-Or, Z., Samanci, B., Lis, P., Tocino, T., Amouri, R., Ben Sassi, S., Hentati, F., Tonelli, F., Alessi, D. R., Farrer, M. J.
10.1101/2024.01.17.24300927 — Posted: 2024-01-18
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinsons disease
Khan, S. S., Jaimon, E., Lin, Y.-E., Nikoloff, J., Tonelli, F., Alessi, D. R., Pfeffer, S. R.
10.1101/2024.01.15.575737 — Posted: 2024-01-16
Pathways controlling neurotoxicity and proteostasis in mitochondrial complex I deficiency
Nithianadam, V., Sarkar, S., Feany, M. B.
10.1101/2024.01.08.574634 — Posted: 2024-01-08
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system
Raimi, O., Ojha, H., Ehses, K., Dederer, V., Lange, S., Rivera, C. P., Deegan, T., Chen, Y., Wightman, M., Toth, R., Labib, K., Mathea, S., Ranson, N., Fernandez-Busnadiego, R., Muqit, M.
10.1101/2023.12.23.573181 — Posted: 2024-01-02
Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo
Coughlin, G. M., Borsos, M., Appling, N., Barcelona, B. H., Mayfield, A. M. H., Mackey, E. D., Eser, R. A., Chen, X., Kumar, S. R., Gradinaru, V.
10.1101/2023.12.23.573214 — Posted: 2023-12-24
Synchronous Measurements of Extracellular Action Potentials and Neurochemical Activity with Carbon Fiber Electrodes in Nonhuman Primates
Amjad, U., Choi, J., Gibson, D. J., Murray, R., Graybiel, A. M., Schwerdt, H. N.
10.1101/2023.12.23.573130 — Posted: 2023-12-24
Characterizing enteric neurons in Dopamine Transporter (DAT)-Cre reporter micereveals dopaminergic subtypes with dual-transmitter content
Recinto, S., Premachandran, S., Mukherjee, S., McDonald, A., Allot, A., Gruenheid, S., Trudeau, L. E., Stratton, J. A.
10.1101/2023.06.16.545271 — Posted: 2023-12-23

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