Channel:  Aligning Science Across Parkinson's (ASAP)

425 Articles

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Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and Parkinsonian motor deficits
Sanchiz-Calvo, M., Coccia, E., Cawthorne, C., Parfitt, G., Van Laere, K., Torre-Muruzabal, T., Cabezudo, D., Tsafaras, G., Cascalho, A., Van Den Haute, C., Vangheluwe, P., Blanchard, J., Bentea, E., Baekelandt, V.
10.1101/2024.07.09.602700 — Posted: 2024-07-13
SynBot: An open-source image analysis software for automated quantification of synapses
Savage, J. T., Ramirez, J., Risher, W. C., Wang, Y., Irala, D., Eroglu, C.
10.1101/2023.06.26.546578 — Posted: 2024-07-12
The Pgb1 locus controls glycogen aggregation in astrocytes of the aged hippocampus without impacting cognitive function
Gomez-Pascual, A., Glikman, D. M., Ng, H. X., Tomkins, J. E., Lu, L., Xu, Y., Ashbrook, D. G., Kaczorowski, C., Kempermann, G., Killmar, J., Mozhui, K., Ohlenschlaeger, O., Aebersold, R., Ingram, D. K., Williams, E. G., Williams, R. W., Overall, R. W., Jucker, M., de Bakker, D. E. M.
10.1101/2023.11.22.567373 — Posted: 2024-07-08
Global Perspectives on Returning Genetic Research Results in Parkinson's Disease
Tan, A. H., Saffie-Awad, P., Schuh, A. F. S., Lim, S.-Y., Madoev, H., Ahmad-Annuar, A., Solle, J., Wegel, C. E., Doquenia, M. L., Dey, S., Perinan, M. T., Makarious, M. B., Fiske, B., Morris, H. R., Noyce, A. J., Kumar, K. R., Klein, C.
10.1101/2024.07.06.24309029 — Posted: 2024-07-07
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4
Feringa, F. M., Koppes-den Hertog, S. J., Wang, L., Derks, R. J. E., Kruijff, I., Erlebach, L., Heijneman, J., Miramontes, R., Pömpner, N., Blomberg, N., Olivier-Jimenez, D., Johanson, L. E., Cammack, A. J., Giblin, A., Toomey, C. E., Rose, I. V. L., Yuan, H., Ward, M. E., Isaacs, A., Kampmann, M., Kronenberg-Versteeg, D., Lashley, T., Thompson, L. M., Ori, A., Mohammed, Y., Giera, M., van der Kant, R. H. N.
10.1101/2024.07.01.601474 — Posted: 2024-07-03
Functional efficacy of the MAO-B inhibitor safinamide in murine substantia nigra pars compacta dopaminergic neurons in vitro: a comparative study with tranylcypromine
Zarrilli, B., Giacomet, C., Cossa, F., Federici, M., Berretta, N., Mercuri, N. B.
10.1101/2024.05.28.596142 — Posted: 2024-06-26
Pathogenic LRRK2 mutations cause loss of primary cilia and Neurturin in striatal Parvalbumin interneurons
Lin, Y.-E., Jaimon, E., Tonelli, F., Pfeffer, S. R.
10.1101/2024.06.17.599289 — Posted: 2024-06-25
Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum
Brill-Weil, S. G., Kramer, P. F., Yanez, A., Clever, F. H., Zhang, R., Khaliq, Z. M.
10.1101/2024.06.25.600616 — Posted: 2024-06-25
Dissociation of novel open loop from ventral putamen to motor areas from classic closed loop in humans II: task-based function
Dundon, N. M., Rizor, E., Stasiak, J., Wang, J., Sabugo, K., Villaneuva, C., Barandon, P., Bostan, A. C., Lapate, R. C., Grafton, S. T.
10.1101/2024.06.18.599622 — Posted: 2024-06-22
Transcriptional pathobiology and multi-omics predictors for Parkinson's disease
Hu, R., Wang, R., Yuan, J., Lin, Z., Hutchins, E., Landin, B., Liao, Z., Liu, G., Scherzer, C. R., Dong, X.
10.1101/2024.06.18.599639 — Posted: 2024-06-21

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