Channel:  Aligning Science Across Parkinson's (ASAP)

512 Articles

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Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson's disease
Gaertner, Z., Oram, C., Schneeweis, A., Schonfeld, E., Bolduc, C., Chen, C., Dombeck, D. A., Parisiadou, L., Poulin, J. F., Awatramani, R.
10.1101/2024.06.06.597807 — Posted: 2024-12-22
Anxa1+ dopamine neuron vulnerability defines prodromal Parkinson's disease bradykinesia and procedural motor learning impairment
Mantas, I., Contestabile, A., Skara, V., Loiseau, C., Santos, I., Cramb, K., Filograna, R., Wade-Martins, R., Magill, P., Meletis, K.
10.1101/2024.12.22.629963 — Posted: 2024-12-22
The gut microbiome promotes mitochondrial respiration in the brain of a Parkinson's disease mouse model
Morais, L. H., Stiles, L., Freeman, M., Oguienko, A. D., Hoang, J. D., Jones, J., Quan, B., Devine, J., Bois, J. S., Chou, T.-F., Trinh, J., Picard, M., Gradinaru, V., Mazmanian, S. K.
10.1101/2024.12.18.629251 — Posted: 2024-12-21
The pyrethroid insecticide deltamethrin disrupts neuropeptide and monoamine signaling pathways in the gastrointestinal tract
White, A. C., Krout, I. N., Mouhi, S., Chang, J., Kelly, S. D., Caudle, W. M., Sampson, T.
10.1101/2024.12.14.628386 — Posted: 2024-12-17
Parkinson's Disease Pathogenic Variants: Cross-Ancestry Analysis and Microarray Data Validation
Hong, S., Koretsky, M. J., Lichtenberge, J., Leonard, H., Pitz, V., Global Parkinson's Genetics Program (GP2)
10.1101/2024.12.16.24319097 — Posted: 2024-12-17
Severe GBA1 variants drive the GBA-PD clinical phenotype: implications for counselling and clinical trials
Menozzi, E., Lucas Del Pozo, S., Macnaughtan, J., Mezabrovschi, R., Koletsi, S., Mitrotti, P., Gallo, L., Calabrese, R., Toffoli, M., Loefflad, N., Valzania, F., Cavallieri, F., Fioravanti, V., Yalkic, S., Limbachiya, N., Blandini, F., Avenali, M., Schapira, A. H.
10.1101/2024.12.09.24318560 — Posted: 2024-12-16
Exploring the relationship between GBA1 host genotype and gut microbiome in the GBA1L444P/WT mouse model: Implications for Parkinson disease pathogenesis
Menozzi, E., Geiger, M., Meslier, V., Fierli, F., Gilles, M., Chau, K.-Y., David, A., Shahar Golan, R., Famechon, A., Koletsi, S., Morabito, C., Quinquis, B., Pons, N., Ehrlich, S. D., Macnaughtan, J., Almeida, M., Schapira, A. H.
10.1101/2024.12.15.627490 — Posted: 2024-12-15
Impact of dopamine deficiency and REM sleep behavior disorder on cognition in early neuronal synuclein disease with hyposmia
Weintraub, D., Nair, A. R., Kurth, R., Brumm, M. C., York, M. K., Dobkin, R., Marek, K., Tanner, C. M., Simuni, T., Siderowf, A., Galsko, D., Chahine, L. M., Coffey, C., Merchant, K., Poston, K. L., Foroud, T., Mollenhauer, B., Brown, E. G., Kieburtz, K., Frasier, M., Sherer, T., Chowdhury, S., Alcalay, R. N., Videnovic, A., on behalf of the Parkinsons Progression Markers Initiative
10.1101/2024.12.12.24318917 — Posted: 2024-12-13
Smell testing to identify early alpha-synucleinopathy among people with dream enactment behavior
Brown, E., Chahine, L. M., Videnovic, A., Marshall, M. J., Kurth, R., Caspell-Garcia, C., Brumm, M. C., Coffey, C., Siderowf, A., Simuni, T., Marek, K., Tanner, C. M., on behalf of the Parkinsons Progression Markers Initiative
10.1101/2024.12.11.24318857 — Posted: 2024-12-12
LRRK2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis
Pei, J., Oliveira, N. L., Recinto, S. J., Kazanova, A., Queiroz-Junior, C. M., Li, Z., Couto, K., Westfall, S., King, I. L., Ribeiro, C. T., Milnerwood, A., Desjardins, M., Thanabalasuriar, A., STRATTON, J. A., Gruenheid, S.
10.1101/2024.11.26.625468 — Posted: 2024-12-02

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