Channel:  Aligning Science Across Parkinson's (ASAP)

518 Articles

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Dystonia-Parkinsonism Gene Variants in Individuals with Parkinsonism and Brain Scans without Evidence for Dopaminergic Deficit (SWEDD)
Nudelman, K. N. H., Xiong, Y., Cook, L., Schulze, J., Abreu, M., Marek, K., Singleton, A., Foroud, T., Chahine, L., The Parkinson s Progression Markers Initiative
10.1101/2022.03.21.22271781 — Posted: 2022-03-21
Structural and biochemical insights into lipid transport by VPS13 proteins.
Adlakha, J., Hong, Z., Li, P., Reinisch, k. M.
10.1101/2022.03.11.484024 — Posted: 2022-03-12
In situ architecture of the lipid transport protein VPS13C at ER-lysosomes membrane contacts
Cai, S., Wu, Y., Guillen-Samander, A., Hancock-Cerutti, W. F., Liu, J., De Camilli, P.
10.1101/2022.03.08.482579 — Posted: 2022-03-08
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
Saha, I., Yuste-Checa, P., da Silva Padilha, M., Guo, Q., Körner, R., Holthusen, H., Trinkaus, V. A., Dudanova, I., Fernandez-Busnadiego, R., Baumeister, W., Sanders, D. W., Gautam, S., Diamond, M. I., Hartl, F.-U., Hipp, M. S.
10.1101/2022.02.18.481043 — Posted: 2022-02-19
Highly efficient generation of isogenic pluripotent stem cell models using prime editing
Li, H., Busquets, O., Verma, Y., Syed, K. M., Kutnowski, N., Pangilinan, G. R., Gilbert, L., Bateup, H., Rio, D. C., Hockemeyer, D., Soldner, F.
10.1101/2022.02.15.480601 — Posted: 2022-02-15
Single-cell transcriptomic and proteomic analysis of Parkinson's disease Brains
Zhu, B., Park, J.-M., Coffey, S., Hsu, I.-U., Lam, T. T., Gopal, P. P., Ginsberg, S. D., Wang, J., Su, C., Zhao, H., Hafler, D. A., Chandra, S., Zhang, L.
10.1101/2022.02.14.480397 — Posted: 2022-02-14
Dopamine transporter and synaptic vesicle sorting defects initiate auxilin-linked Parkinson's disease
Vidyadhara, D. J., Somayaji, M., Wade, N., Yücel, B., Zhao, H., Shashaank, N., Ribaudo, J., Gupta, J., Lam, T. T., Sames, D., Greene, L. E., Sulzer, D. L., Chandra, S. S.
10.1101/2022.02.04.479203 — Posted: 2022-02-06
A mono- and intralink filter (mi-filter) to improve false-discovery rates in cross-linking mass spectrometry data
Chen, X., Sailer, C., Kammer, K.-M., Fuersch, J., Eisele, M. R., Sakata, E., Stengel, F.
10.1101/2022.02.03.478943 — Posted: 2022-02-03
Structural basis for Parkinson's Disease-linked LRRK2's binding to microtubules
Snead, D. M., Matyszewski, M., Dickey, A. M., Lin, Y. X., Leschziner, A. E., Reck-Peterson, S. L.
10.1101/2022.01.21.477284 — Posted: 2022-01-22
Intravenous gene transfer throughout the brain of infant Old World primates using AAV
Chuapoco, M. R., Flytzanis, N., Goeden, N., Octeau, J. C., Roxas, K. M., Chan, K. Y., Scherrer, J., Winchester, J., Blackburn, R. J., Campos, L. J., Arokiaraj, C. M., Miles, T. F., Jang, M. J., Vendemiatti, J., Deverman, B. E., Pickel, J., Fox, A. S., Gradinaru, V.
10.1101/2022.01.08.475342 — Posted: 2022-01-09

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